A5071260826- Vaccine Coverage and Hesitancy
- Immune responses and vaccinations
- Virology and Viral Diseases
- Travel-related health issues
- Viral gastroenteritis research and epidemiology
- Hepatitis Viruses Studies and Epidemiology
- Bacillus and Francisella bacterial research
- Influenza Virus Research Studies
- COVID-19 epidemiological studies
- Bacterial Infections and Vaccines
- Viral Infections and Outbreaks Research
- Herpesvirus Infections and Treatments
- Disaster Response and Management
- Poxvirus research and outbreaks
- Agricultural Systems and Practices
- vaccines and immunoinformatics approaches
- SARS-CoV-2 and COVID-19 Research
- Parasites and Host Interactions
- Rangeland Management and Livestock Ecology
- Livestock Management and Performance Improvement
- Global Maternal and Child Health
- Climate Change and Health Impacts
- Migration, Health and Trauma
- Rabies epidemiology and control
- Pneumonia and Respiratory Infections
University of California, Los Angeles
2017-2023
Walter Reed Army Institute of Research
2022
United States Army Medical Research Directorate - Georgia
2022
United States Army
2022
Armed Forces Health Surveillance Center
2020-2021
UCLA Health
2020
Fielding Graduate University
2017-2019
The Ohio State University
2010
Measles is a significant contributor to child mortality in the Democratic Republic of Congo (DRC), despite routine immunization programs and supplementary activities (SIA). Further, national coverage levels may hide disparities among certain groups children, making effective measles control even more challenging. This study describes vaccination reporting methods identifies predictors children participating 2013–2014 DRC Demographic Health Survey (DHS). We examined 6947 aged 6–59 months. A...
U.S. military personnel must be ready to deploy locations worldwide, including environments with heightened risk of infectious disease. Diarrheal illnesses continue among the most significant disease threats operational capability. To better prevent, detect, and respond these improve synchronization across Department Defense (DoD) overseas laboratory network, a multisite Global Travelers' Diarrhea protocol was implemented standardized case definitions harmonized methods identify enteric...
Transient immunosuppression and increased susceptibility to other infections after measles infection is well known, but recent studies have suggested the occurrence of an "immune amnesia" that could long-term immunosuppressive effects.We examined association between past acute episodes fever, cough, diarrhea among 2350 children aged 9 59 months whose mothers were selected for interview in 2013-2014 Democratic Republic Congo (DRC) Demographic Health Survey (DHS). Classification who had was...
Schistosomiasis afflicts an estimated 10 million pregnant women in Africa annually. With mounting evidence of adverse impacts to reproductive health resulting from urogenital schistosomiasis, including increased transmission HIV, further research on prenatal disease epidemiology is warranted, with implications for maternal and fetal health. Between October 2016 March 2017, we conducted a cross-sectional study examining the prevalence schistosomiasis its association sexually transmitted...
Despite increased vaccination rates, the burden, morbidity and mortality associated with vaccine preventable diseases remains high. In Democratic Republic of Congo (DRC), potentially unreliable data geographically varied program provision call for a better understanding coverage its changes over time at country province level. To assess in proportion children who were fully vaccinated DRC, histories 12-59 months age obtained from both 2007 2013-2014 Demographic Health Surveys (DHS). Changes...
Travelers' diarrhea has a high incidence rate among deployed US military personnel and can hinder operational readiness. The Global Diarrhea study is Department of Defense--funded multisite surveillance effort to investigate the etiology epidemiology travelers' diarrhea. During 2018-2023, we enrolled 512 participants at partner institutions in 6 countries: Djibouti, Georgia, Egypt, Honduras, Nepal, Peru. Harmonized laboratory methods conducted each institution identified >1 pathogens,...
Background: Recent studies suggest measles-induced immune amnesia could have long-term immunosuppressive effects via preferential depletion of memory CD150+ lymphocytes, and associations with a 2–3 year period increased mortality morbidity from infectious diseases other than measles has been shown in children wealthy low-income countries. To further examine the previous virus infection may on immunologic among Democratic Republic Congo (DRC), we assessed tetanus antibody levels fully...
Background Tetanus is a potentially fatal disease that preventable through vaccination. While the Democratic Republic of Congo (DRC) has continued to improve implementing routine vaccination activities throughout country, they have struggled maintain high childhood vaccine coverage. This study aims examine seroprevalence tetanus in children 6 59 months identify areas for intervention and improvement Methods In collaboration with 2013–2014 Demographic Health Survey, we assessed antibodies...
Measles is endemic in the Democratic Republic of Congo (DRC), and 89–94% herd immunity required to halt its transmission. Much World Health Organization African Region, including DRC, has vaccination coverage below 95% level eliminate measles, heightening concern inadequate measles immunity. We assessed 6706 children aged 6–59 months whose mothers were selected for interview 2013–2014 DRC Demographic Survey. History was obtained by maternal report, classification who had completed using...
The critical evaluation of immunization programs is key to identifying areas suboptimal vaccination coverage, monitoring activities, and aiding development public health policy. For vaccine effectiveness, direct antibody binding assay methods, including enzyme immunoassay, enzyme-linked fluorescence assays, indirect immunofluorescence assay, are most commonly used for detection IgG antibodies. However, despite their well-demonstrated, reliable performance, they can be labor-intensive...
Travelers' diarrhea (TD) is one of the most common illnesses affecting modern-day travelers, including military personnel. Previous work has shown that afflicted travelers may alter their itineraries and be confined to bed rest due symptoms, personnel become incapable completing operational requirements. Examination signs, severity diarrheagenic pathogens can inform clinical diagnosis prioritization future surveillance research activities. Utilizing a global laboratory network, culture...
Abstract Background Ebola virus disease ( EVD ) can be clinically severe and highly fatal, making surveillance efforts for early detection of paramount importance. In areas with limited access to laboratory testing, the Integrated Disease Surveillance Response IDSR strategy in Democratic Republic Congo DRC may a vital tool improving outbreak response. Methods Using data from nation's four periods 2007–2014, we assessed trends Viral Hemorrhagic Fever VHF differential diagnoses reportable...
Abstract Background Recent studies suggest a measles-induced immune amnesia that could have long-term immunosuppressive effects via preferential depletion of memory B and T CD150+ lymphocytes. Methods We examined the association between past measles tetanus antibody levels among children participating in 2013–2014 Democratic Republic Congo (DRC) Demographic Health Survey (DHS). Our sample consisted 833 aged 6–59 months whose mothers were selected for interview. Mothers reported (via recall)...
Acute diarrhea (AD) can have significant impacts on military troop readiness. Medical providers must understand current trends of enteropathogen antimicrobial resistance (AMR) in service members (SMs) to inform proper, timely treatment options. However, little is known enteric pathogen profiles across the Military Health System (MHS). The primary objectives this study were identify gaps surveillance within MHS, describe epidemiology AMR pathogens, and MHS both Continental United States...
ABSTRACT Introduction This analysis evaluates potential reporting discrepancies of the DD2341 Form (Report Animal Bite—Potential Rabies Exposure) submitted to a forward-deployed Advisory Board Theater Medical Data Store (TMDS) and Reportable Event (RME) systems identify gaps that can lead improved best practices ensure documentation Post Exposure Prophylaxis (PEP) rabies exposures into service members (SMs) electronic medical records. Materials Methods The project compares number Service...