Guillaume Ngoie Mwamba

ORCID: 0000-0003-0460-877X
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About
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Research Areas
  • Vaccine Coverage and Hesitancy
  • COVID-19 epidemiological studies
  • Virology and Viral Diseases
  • Viral Infections and Immunology Research
  • Viral Infections and Outbreaks Research
  • Viral gastroenteritis research and epidemiology
  • Global Maternal and Child Health
  • Immune responses and vaccinations
  • Zoonotic diseases and public health
  • Rabies epidemiology and control
  • Child Nutrition and Water Access
  • Viral Infections and Vectors
  • Poverty, Education, and Child Welfare
  • Healthcare Systems and Practices
  • Food Security and Health in Diverse Populations
  • COVID-19 and Mental Health
  • Poxvirus research and outbreaks
  • Primary Care and Health Outcomes
  • Influenza Virus Research Studies
  • Whipple's Disease and Interleukins
  • Healthcare Systems and Reforms
  • Herpesvirus Infections and Treatments
  • SARS-CoV-2 and COVID-19 Research
  • Blood groups and transfusion
  • Migration, Health and Trauma

University of Kamina
2020-2024

Ministry of Public Health
2016-2024

VillageReach
2023-2024

Agence de Médecine Préventive
2019-2020

National Institute of Biomedical Research
2017

University of California, Los Angeles
2017

Gates Foundation
2017

Purpose: This study aims to estimate the acceptability of a future vaccine against COVID-19 and associated factors if offered in Congolese health-care workers (HCWs), since they have highest direct exposure disease. Patients Methods: We conducted an analytical cross-sectional among 23 referral hospitals, including three university located towns from March through 30 April 2020. The main outcome variable was healthcare workers' acceptance COVID-19. vaccination willingness were identified...

10.2147/por.s271096 article EN cc-by-nc Pragmatic and Observational Research 2020-10-01

Background: Adherence to public health instructions for the COVID-19 is important controlling transmission and pandemic's economic impacts. The aim of this study was determine associated factors non-adherence social measures instructions. Methods: This a cross-sectional conducted with 1913 participants in two provinces DRC, Mbuji-Mayi, Kamina. Predictors preventive were identified using binary logistic regression analysis. P -value< 0.05 considered as significant predictor. Results: Among...

10.2147/jmdh.s274944 article EN cc-by-nc Journal of Multidisciplinary Healthcare 2020-10-01

<h3>Background:</h3> The immunization system in the Democratic Republic of Congo faces many challenges, including persistent large-scale outbreaks polio, measles, and yellow fever; a large number unvaccinated children for all antigens; minimal delayed funding; poor use data at levels. In response, Expanded Programme on Immunization within Ministry Health (MOH) collaborated with global partners to develop revitalization strategy routine (RI) called Mashako Plan. <h3>Mashako Plan Design...

10.9745/ghsp-d-22-00326 article EN cc-by Global Health Science and Practice 2023-04-12

Low immunization coverage rates in the Democratic Republic of Congo (DRC) have been reflective challenges with vaccine access, support and delivery country. Motivated by measles vaccine-derived polio virus (VDPV) outbreaks 2016-17 low vaccination rates, provinces Haut Lomami Tanganyika were identified as pilot locations for an innovative approach focused on establishing a consortium partners supporting local government. This was formalized through Memorandums Understanding (MoUs) between...

10.1016/j.vaccine.2023.11.029 article EN cc-by Vaccine 2023-11-19

Despite more than 300,000 rVSVΔG-ZEBOV-glycoprotein (GP) vaccine doses having been administered during Ebola virus disease (EVD) outbreaks in the Democratic Republic of Congo (DRC) between 2018 and 2020, seroepidemiologic studies vaccinated Congolese populations are lacking. This study examines antibody response at 21 d 6 mo postvaccination after single-dose rVSVΔG-ZEBOV-GP vaccination among EVD-exposed potentially exposed DRC. We conducted a longitudinal cohort 608...

10.1073/pnas.2118895119 article EN cc-by Proceedings of the National Academy of Sciences 2022-02-02

Despite increased vaccination rates, the burden, morbidity and mortality associated with vaccine preventable diseases remains high. In Democratic Republic of Congo (DRC), potentially unreliable data geographically varied program provision call for a better understanding coverage its changes over time at country province level. To assess in proportion children who were fully vaccinated DRC, histories 12-59 months age obtained from both 2007 2013-2014 Demographic Health Surveys (DHS). Changes...

10.1371/journal.pone.0217426 article EN public-domain PLoS ONE 2019-05-24

Introduction: vaccination coverage of the first dose diphtheria-tetanus-pertussis-hepatitis B-Haemophilus influenza type b (pentavalent) vaccine for City-Province Kinshasain years 2012 - 2014 wasbelow national objective 92%, with less than 80% reported in 12 35 health zones (HZ). The purpose this study was to discern potential contributing factors low Kinshasa.

10.11604/pamj.supp.2017.27.3.11930 article EN cc-by Pan African Medical Journal 2017-01-01

Background: Malnutrition is identified as a risk-factor for insufficient polioseroconversion in the context of vaccine-derived polio virus (VDPV) outbreak prone region. To assess prevalence malnutrition and its link to poliovirus immunity, cross-sectional household survey was conducted regions Haut- Lomami Tanganyika, DRC. Methods: In March 2018, we included 968 healthy children aged 6 59 months from eight out 27 districts. Selection study locations within these districts done using...

10.2147/jmdh.s437351 article EN cc-by-nc Journal of Multidisciplinary Healthcare 2024-03-01

While generally mild in children, rubella infection early pregnancy can lead to miscarriage, fetal death or congenital syndrome. Rubella vaccination is not yet available as a part of routine immunization the Democratic Republic Congo (DRC), and burden unknown.In collaboration with 2013-2014 DRC Demographic Health Survey, serosurvey was carried out assess population immunity vaccine-preventable diseases. Dry blood spot samples collected from children 6-59 months age were processed using Dynex...

10.1097/inf.0000000000001703 article EN The Pediatric Infectious Disease Journal 2017-07-25

Mumps is an acute viral infection and while the usually mild, complications can lead to permanent sequelae including brain damage deafness. The burden of mumps currently unknown Democratic Republic Congo (DRC), we therefore assessed susceptibility among children 6-59 months age.In collaboration with 2013-2014 DRC Demographic Health Survey, conducted a serosurvey assess population immunity vaccine preventable diseases. Dried blood spot samples were collected from 6 59 age processed at...

10.1097/inf.0000000000001483 article EN The Pediatric Infectious Disease Journal 2016-12-20

Measles is endemic in the Democratic Republic of Congo (DRC), and 89–94% herd immunity required to halt its transmission. Much World Health Organization African Region, including DRC, has vaccination coverage below 95% level eliminate measles, heightening concern inadequate measles immunity. We assessed 6706 children aged 6–59 months whose mothers were selected for interview 2013–2014 DRC Demographic Survey. History was obtained by maternal report, classification who had completed using...

10.1016/j.vaccine.2019.09.047 article EN cc-by Vaccine 2020-02-01

Varicella zoster virus (VZV) causes both varicella (chickenpox) and herpes (shingles) is associated with significant global morbidity. Most epidemiological data on VZV come from high-income countries, to date there are limited the burden of in Africa.We assessed seroprevalence antibodies among children Democratic Republic Congo collaboration 2013-2014 Demographic Health Survey. Dried blood spot samples collected 6-59 months age were run Dynex™ Technologies Multiplier FLEX® chemiluminescent...

10.1097/inf.0000000000001750 article EN The Pediatric Infectious Disease Journal 2017-08-23

Rubella vaccine has yet to be introduced into the national immunization schedule of Democratic Republic Congo (DRC); current burden congenital rubella syndrome (CRS) is unknown and likely high. An important consideration prior introducing containing (RCV) potential inverse relationship between RCV coverage CRS incidence. Increasing will also increase in average age infection. Cumulative infections across all groups decrease, but number vulnerable may increase.Rubella transmission dynamics...

10.1016/j.jvacx.2021.100127 article EN cc-by Vaccine X 2021-11-12

Health facility (HF) and household (HH) data can complement each other to provide a better understanding of the factors that contribute vaccination status. In 12 zones with low coverage within Kinshasa Province, Democratic Republic Congo, we conducted 2 surveys: (1) linked HH HF survey among 6-11-month-old infants, (2) 12-23-month-old children. Linked objectives were identify associated status explore methodological considerations for implementation. To data, enrolled infants in clusters...

10.1093/infdis/jix125 article EN cc-by The Journal of Infectious Diseases 2017-03-10

Malnutrition is identified as a risk factor for insufficient polio seroconversion in the context of vaccine-derived poliovirus (VDPV) outbreak-prone region. In Democratic Republic Congo (DRC), underweight decreased from 31% (in 2001) to 26% 2018). Since 2004, VDPV serotype 2 outbreaks (cVDPV2) have been documented and were geographically limited around Haut-Lomami Tanganyika Provinces.

10.2147/por.s437485 article EN Pragmatic and Observational Research 2023-12-01

Despite the successes in wild-type polio eradication, poor vaccine coverage DRC has led to occurrence of circulating vaccine-derived poliovirus outbreaks. This cross-sectional population-based survey provides an update previous poliovirus-neutralizing antibody seroprevalence studies and quantifies risk factors for under-immunization parental knowledge that guide decision making. Among 964 children between 6 35 months our survey, 43.8% (95% CI: 40.6–47.0%), 41.1% (38.0–44.2%), 38.0%...

10.3390/vaccines12030246 article EN cc-by Vaccines 2024-02-27

In response to the challenge of maintaining COVID-19 vaccination coverage amidst pandemic, VillageReach, in collaboration with Ministry Public Health Prevention and Hygiene Kinshasa, DRC, integrated routine immunization services at two primary healthcare facilities. This initiative, launched July 2022, represented first its kind aiming assess effectiveness scalability a multimodal approach.

10.1016/j.vaccine.2024.126392 article EN cc-by-nc-nd Vaccine 2024-10-05

Immunisation is a high priority for improving health outcomes. Yet, in many low-income and middle-income countries, achieving coverage targets independently hindered by lack of domestic resources reliance on partners’ support. Both the 2001 Abuja Declaration 2016 Addis were key political commitments to immunisation coverage; however, signatories have yet meet international targets. Despite signing Global Vaccine Action Plan Declaration, Democratic Republic Congo (DRC) was unable fully...

10.1136/bmjgh-2024-015675 article EN cc-by-nc-nd BMJ Global Health 2024-10-01

Objectif : Le but de ce travail était d’analyser les effets d’une assistance technique sur la performance du programme vaccination dans dix districts sanitaires Côte d’Ivoire ayant le plus grand nombre d’enfants non vaccinés contre rougeole. Méthode Ces ont bénéficié quatre supervisions formatives et d’un appui en logistique gestion qualité des données entre juin 2016 mai 2017. Nous avons suivi l’évolution indicateurs vaccinale chaque district ciblé, puis nous comparés à ceux autres...

10.3917/spub.191.0177 article FR Santé Publique 2019-05-14
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