A5086248289- Vaccine Coverage and Hesitancy
- Viral Infections and Outbreaks Research
- COVID-19 epidemiological studies
- Virology and Viral Diseases
- Immune responses and vaccinations
- HIV, Drug Use, Sexual Risk
- Viral Infections and Vectors
- Poxvirus research and outbreaks
- Sex work and related issues
- Bacillus and Francisella bacterial research
- SARS-CoV-2 and COVID-19 Research
- Disaster Response and Management
- Viral gastroenteritis research and epidemiology
- Herpesvirus Infections and Treatments
- HIV/AIDS Research and Interventions
- Hepatitis B Virus Studies
- Viral Infections and Immunology Research
- Rabies epidemiology and control
- Cervical Cancer and HPV Research
- Census and Population Estimation
- SARS-CoV-2 detection and testing
- Global Maternal and Child Health
- Respiratory viral infections research
- Migration, Health and Trauma
- Zoonotic diseases and public health
World Health Organization Regional Office for Africa
2024
Centers for Disease Control and Prevention
2018-2024
AID Atlanta
2024
University of California, Los Angeles
2011-2023
IQVIA (United States)
2023
Center for Global Health
2018-2022
Fielding Graduate University
2017-2021
Louisiana State Department of Health and Hospitals
2021
National Center for Immunization and Respiratory Diseases
2021
Epidemic Intelligence Service
2018-2020
Monkeypox, caused by a zoonotic orthopoxvirus, is endemic in Central and West Africa. Monkeypox has been sporadically reported the Republic of Congo. During March 22-April 5, 2017, we investigated 43 suspected human monkeypox cases. We interviewed case-patients collected dried blood strips vesicular crust specimens (active lesions), which tested for orthopoxvirus antibodies ELISA virus varicella zoster DNA PCR. An ecologic investigation was conducted around Manfouété, from 105 small mammals...
On August 1, 2018, the Democratic Republic of Congo Ministry Health (DRC MoH) declared tenth outbreak Ebola virus disease (Ebola) in DRC, North Kivu province eastern DRC on border with Uganda, 8 days after another was over northwest Équateur province. During mid- to late-July a cluster 26 cases acute hemorrhagic fever, including 20 deaths, reported province.* Blood specimens from six patients hospitalized Mabalako health zone and sent Institut National de Recherche Biomédicale (National...
With the availability of authorized COVID-19 vaccines in early 2021, vaccination became an effective tool to reduce COVID-19-associated morbidity and mortality.Initially, World Health Organization (WHO) set ambitious target vaccinate 70% global population by mid-2022.However, July 2022, WHO recommended that all countries, including those African Region, prioritize high-risk groups, older adults health care workers, have greatest impact on mortality.As December 31, 2023, approximately 860...
Ebola virus disease (Ebola) is a rare but severe illness in humans, with an average case fatality rate of approximately 50%.Two licensed vaccines are currently available against Orthoebolavirus zairense, the that causes Ebola: 1-dose rVSVΔG-ZEBOV-GP (ERVEBO [Merck]) and 2-dose regimen Ad26.ZEBOV MVA-BN-Filo (Zabdeno/ Mvabea [Johnson & Johnson]).The Strategic Advisory Group Experts on Immunization recommends use ERVEBO during outbreaks, 2021, global stockpile was established to ensure...
ABSTRACT Aim To examine whether a brief bout of moderate intensity exercise reduces alcohol urges and mood disturbance in those with dependence. Design A counterbalanced cross‐over design (within‐subjects). Setting hospital‐based rehabilitation clinic. Participants Twenty males females [mean (SD) age = 40.1 (8.2) years, mean Severity Alcohol Dependence Questionnaire score 34.2 (13.4)] who had recently completed detoxification days since completing 3.5 (2.3)]. Intervention On the first day...
Evaluating the effectiveness of a surveillance system, and how it improves over time has significant implications for disease control prevention. In Democratic Republic Congo (DRC), Integrated Disease Surveillance Response (IDSR) was implemented to estimate burden disease, monitor changes in occurrence, inform resource allocation. For this effort we utilized national passive data from DRC's IDSR explore reporting trends human monkeypox (MPX) 2001 2013.We obtained on MPX cases occurring...
These two authors contributed equally.† COVID-19-related signs and symptoms include subjective fever, cough, shortness of breath, chills, muscle aches, headache, sore throat, loss taste, or smell.https://www.cdc.gov/coronavirus/2019-ncov/symptoms-testing/symptoms
The first reported outbreak of Ebola virus disease occurred in 1976 Yambuku, Democratic Republic Congo. Antibody responses survivors 11 years after infection have been documented. However, this report is the characterization anti-Ebola antibody persistence and neutralization capacity 40 infection. Using ELISAs we measured survivor's immunological response to Zaire (EBOV) glycoprotein nucleoprotein, assessed VP40 reactivity. Neutralization EBOV was using a pseudovirus approach plaque...
Abstract A brief bout of aerobic exercise (e.g. stationary bicycle) has been shown to result in an acute reduction tobacco withdrawal symptoms and cravings abstinent smokers. However, is often not practical it interest examine whether non‐aerobic a similar effect. We investigated isometric (involving muscular contractions against resistance without movement, e.g. placing the palms hands together pushing) reduces desire smoke symptoms. Following overnight abstinence smokers were randomized...
Previous studies suggest that cases of Ebola virus disease (EVD) may go unreported because they are asymptomatic or unrecognized, but evidence is limited by study designs and sample size.A large population-based survey was conducted (n = 3415) to assess animal exposures behaviors associated with Ebolavirus antibody prevalence in rural Kasai Oriental province the Democratic Republic Congo (DRC). Fourteen villages were randomly selected all healthy individuals ≥1 year age eligible.Overall, 11%...
To assess transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a detention facility experiencing disease outbreak and evaluate testing strategies, we conducted prospective cohort investigation Louisiana, USA. We SARS-CoV-2 for detained persons 6 quarantined dormitories at various time points. Of 143 persons, 53 were positive the initial test, an additional 58 later points (cumulative incidence 78%). In 1 dormitory, all 45 initially negative; 18 days later, 40 (89%)...
Introduction During the 2018–2020 Ebola virus disease (EVD) outbreak in eastern part of Democratic Republic Congo (DRC), prevention and control measures, such as vaccination were challenging by community mistrust. We aimed to understand perceptions regarding identify determinants vaccine uptake among HCWs. Methods In March 2021, we conducted a cross-sectional survey 438 HCWs from 100 randomly selected health facilities three zones (Butembo, Beni, Mabalako) affected 10th EVD North Kivu, DRC....
Key populations, including people who inject drugs (PWID), men have sex with (MSM), and female workers (FSW), are disproportionately affected by the HIV epidemic. Understanding magnitude of, informing public health response to, epidemic among these populations requires accurate size estimates. However, low social visibility poses challenges to efforts.The objective of this study was derive population estimates PWID, MSM, FSW in Kampala using capture-recapture.Between June October 2017,...
Measles is a significant contributor to child mortality in the Democratic Republic of Congo (DRC), despite routine immunization programs and supplementary activities (SIA). Further, national coverage levels may hide disparities among certain groups children, making effective measles control even more challenging. This study describes vaccination reporting methods identifies predictors children participating 2013–2014 DRC Demographic Health Survey (DHS). We examined 6947 aged 6–59 months. A...
In 2017, a monkeypox outbreak occurred in Likouala Department, Republic of the Congo. Many affected individuals were Aka ethnicity, hunter-gatherers indigenous to Central Africa who have worse health outcomes comparison with other forest-dwelling peoples. To test hypothesis that people different risk factors for monkeypox, we analyzed questionnaire data 39 suspected cases, comparing and Bantu groups. more likely touch animal urine/feces, find dead animals in/around home, eat an was found...
COVID-19 vaccination in the Democratic Republic of Congo (DRC) began April 2021. A month later, most vaccine doses were reallocated to other African countries, due low uptake and realization that would expire before use. Based on data available 13 August 2022, 2.76% DRC population had been fully vaccinated with last dose primary series vaccine, placing country second Africa five global coverage. The DRC's reliance donations requires continuous adaptation deployment plan match incoming...
Background We investigated progress towards UNAIDS 90-90-90 targets among female sex workers in Kampala, Uganda, who bear a disproportionate burden of HIV. Methods Between April and December 2012, 1,487 workers, defined as women, 15–49 years, residing greater selling for money the last 6 months, were recruited using respondent-driven sampling. Venous blood was collected HIV viral load testing [viral suppression (VLS) <1,000 copies/mL]. data audio computer-assisted self-interviews calculated...
Background: Key populations at higher risk for HIV infection, including people who inject drugs, men have sex with (MSM), and female workers (FSWs), are disproportionately affected by the HIV/AIDS epidemic. Empirical estimates of their population sizes necessary program planning monitoring. Such estimates, however, lacking most Uganda’s urban centers.
The tenth Ebola Virus Disease (EVD) outbreak (2018-2020, North Kivu, Ituri, South Kivu) in the Democratic Republic of Congo (DRC) was second-largest EVD history. During this outbreak, vaccination an integral part response. We evaluated community perceptions toward and identified correlates vaccine uptake among high-risk members DRC. In March 2021, a cross-sectional survey adults implemented three health zones. employed sampling approach mimicking ring vaccination, targeting survivors, their...