A5022396203- Congenital Heart Disease Studies
- Tryptophan and brain disorders
- Cerebrovascular and Carotid Artery Diseases
- Orthopaedic implants and arthroplasty
- Cardiovascular Issues in Pregnancy
- Cardiovascular Function and Risk Factors
- Neuroinflammation and Neurodegeneration Mechanisms
- Stress Responses and Cortisol
- Neurological Disease Mechanisms and Treatments
- Bone fractures and treatments
- Acute Ischemic Stroke Management
- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Circular RNAs in diseases
- Orthopedic Infections and Treatments
- Ophthalmology and Visual Impairment Studies
- Cardiac Valve Diseases and Treatments
- Heart Failure Treatment and Management
- Pregnancy and preeclampsia studies
- Nasal Surgery and Airway Studies
- Polysaccharides and Plant Cell Walls
- Cardiovascular Health and Disease Prevention
- Pulmonary Hypertension Research and Treatments
- Gestational Diabetes Research and Management
- Medical Imaging and Analysis
Yancheng Institute of Technology
2023-2025
Southwest Hospital
2020-2024
Capital Medical University
2015-2024
Beijing Anzhen Hospital
2010-2024
Peking University Third Hospital
2024
Peking University
2024
Nantong University
2016-2024
Affiliated Hospital of Nantong University
2016-2024
Second Affiliated Hospital of Nantong University
2018-2024
Army Medical University
2020-2024
Oxidative stress is associated with many acute and chronic inflammatory diseases, yet limited treatment currently available clinically. The development of enzyme-mimicking nanomaterials (nanozymes) good reactive oxygen species (ROS) scavenging ability biocompatibility a promising way for the ROS-related inflammation. Herein we report simple efficient one-step ultrasmall Cu
Abstract Alzheimer's disease (AD) is a progressively debilitating neurodegenerative condition primarily affecting the elderly. Emerging research suggests that microRNAs (miRNAs) play role in development of AD. This study investigates impact miR‐107‐5p on neurological damage, oxidative stress, and immune responses We utilized APP/PS1 mice as AD mouse models C57BL/6 J controls. received treatment with agomir (to overexpress miR‐107‐5p) or BAY11‐7082 (an NF‐κB pathway inhibitor). evaluated...
ABSTRACT Type 2 diabetes mellitus (T2DM), a widespread chronic metabolic disorder, presents global challenge. Metformin hydrochloride, although widely prescribed, is associated with notable side effects. This study aims to explore safer, more effective alternatives by assessing the impact of Ruditapes philippinarum polysaccharides (RPPs) on glycemic control and modulation microbiota in T2DM mice. A mouse model was established through high‐sucrose/high‐fat diet intraperitioneal streptozotocin...
To assess the effectiveness of a three-stage intervention to reduce caesarean deliveries in Chinese tertiary hospital.A retrospective study was conducted whether educating staff, patients and auditing surgeon practices (introduced 2005) had reduced delivery rates. Multiple logistic regression used check for potential association between rates admission neonatal intensive care unit (NICU).The rate ranged from 53.5% 56.1% 2001-2004 43.9% 36.1% 2005-2011. When 2005-2011 were treated as "before"...
FTE ameliorates symptoms of hyperglycemia by regulating gut microbiota in T2DM mice.
Background Three‐dimensional (3D) printed models have been shown to be promising in surgical training rhinology. The objectives of this study were develop a set 3D‐printed including the pediatric and adult nasal cavity, postsurgical paranasal sinuses, assess face content validity endoscopic training. Methods computed tomography (CT) data patient without disorders an with septal deviation selected produce CT who underwent sinus surgery 4 months ago was chosen create model. After by our...
Abstract Background The treatment of infected bone defects remains a clinical challenge. With the development three-dimensional printing technology, printed implants have been used for defect reconstruction. aim this study was to investigate outcomes porous prosthesis in femoral caused by osteomyelitis. Methods Eleven patients with following osteomyelitis who were treated 3D-printed at our institution between May 2017 and July 2021, included. Eight diagnosed critical-sized defects, other...
We sought to develop a hemodynamic model of aortic and ductal arches using computational fluid dynamics (CFD) 3D/4D spatio-temporal image correlation (STIC) fetal echocardiography investigate the hemodynamics coarctation aorta (CoA) in human fetuses this approach.We obtained STIC echocardiographic images (DA) five normal fetuses. Based on these images, we simulated two CFD. Subsequently, reduced dimensions isthmus from 100% 85%, 70%, 55%, 40%, 25% original dimension digitally. Numerical...
Lysine succinylation is a newly identified protein post-translational modification and plays important roles in various biological pathways both prokaryotes eukaryotes, but its extent function photosynthetic organisms remain largely unknown. Here, we performed the first systematic studies of lysine cyanobacteria, which are only capable oxygenic photosynthesis established model for studying mechanisms. By using mass spectrometry analysis combination with enrichment succinylated peptides from...
Treatment of heart failure with preserved ejection fraction (HFpEF) is urgently needed; however, effective treatments are lacking. Current evidence showed a possible association between the use calcium channel blockers (CCBs) and improved outcomes in HFpEF patients. We aimed to investigate impact CCBs on mortality patients HFpEF.This was post hoc analysis Preserved Cardiac Function Heart Failure an Aldosterone Antagonist Trial. The primary outcome all-cause mortality. secondary were...
Rationale: Sarcomatoid hepatocellular carcinoma (SHC) is a rare malignant tumor composed of both and sarcoma components. It has atypical clinical symptoms high degree malignancy, with rapid progression poor prognosis. Patient concerns: A 63-year-old female patient was admitted to our hospital chief complaint fatigue present for more than 1 month fever 10 days. Diagnoses: This underwent an upper abdominal MRI plain scan enhanced showed solid in the right lobe liver, size approximately 4.7 cm...
Abstract Background Clinical repair of critical-sized bone defects (CBDs) in the tibial diaphysis presents numerous challenges, including inadequate soft tissue coverage, limited blood supply, high load-bearing demands, and potential deformities. This study aimed to investigate clinical feasibility efficacy employing 3D-printed prostheses for repairing CBDs exceeding 10 cm diaphysis. Methods retrospective included 14 patients (11 males 3 females) with an average age 46.0 years. The...