- Magnesium Alloys: Properties and Applications
- Aluminum Alloys Composites Properties
- Respiratory Support and Mechanisms
- Airway Management and Intubation Techniques
- Anesthesia and Sedative Agents
- Anesthesia and Pain Management
- Anesthesia and Neurotoxicity Research
- Spinal Cord Injury Research
- Metal and Thin Film Mechanics
- Hydrogen Storage and Materials
- Aluminum Alloy Microstructure Properties
- Cardiac, Anesthesia and Surgical Outcomes
- Advanced Welding Techniques Analysis
- Oil and Gas Production Techniques
- Nerve injury and regeneration
- Ultrasound in Clinical Applications
- Hydraulic Fracturing and Reservoir Analysis
- Neonatal Respiratory Health Research
- Material Properties and Applications
- Congenital Diaphragmatic Hernia Studies
- Tracheal and airway disorders
- MicroRNA in disease regulation
- Acute Myocardial Infarction Research
- Surface Modification and Superhydrophobicity
- Safety and Risk Management
Shanghai Jiao Tong University
2015-2025
Shanghai Children's Hospital
2015-2025
Beijing Tsinghua Chang Gung Hospital
2015-2025
Tsinghua University
2014-2025
China Animal Health and Epidemiology Center
2025
Shanghai Children's Medical Center
2024
Kunming Medical University
2021-2024
South China Agricultural University
2024
Peking University
2012-2024
Center for Life Sciences
2024
A super high-strength wrought Mg-12.6Gd-1.3Y-0.9Zn-0.5Mn (GWZ1311M, wt%) alloy fabricated by hot extrusion and strain aging is developed. The before including cold rolling or plus stretching results in strong work hardening promotes the precipitation of γ' phase chain-like structures during subsequent aging. While grain sizes texture components different aged samples do not show essential difference, number densities both are much higher strain-aged than those sample without pre-deformation....
Abstract Cerebral cavernous malformations 2 (CCM2) loss is associated with the familial form of CCM disease. The protein kinase MEKK3 (MAP3K3) essential for embryonic angiogenesis in mice and interacts physically CCM2, but how this interaction mediated its relevance to cerebral vasculature are unknown. Here we report that Mekk3 plays an intrinsic role vascular development. Inducible endothelial knockout neonatal lethal due multiple intracranial haemorrhages brain blood vessels leakage. We...
Background & Aims: Deep hypothermic circulatory arrest (DHCA) is a cerebral protection technique that has been used in the operations involving aortic arch and brain aneurysm for decades. We previous showed DHCA treated rats developed significant oxidative stress apoptosis neurons. here intend to investigate protective effect of hydrogen against stress-induced cell injury involved mechanisms using an vitro experimental model hypoxia/reoxygenation (H/R) on HT-22 cells. Methods: The H/R...
We determined the median effective dose and 95% confidence interval (CI) of remimazolam required to inhibit laryngeal mask airway (LMA) insertion reactions combined with sufentanil 0.3 μg/kg in pediatric anesthesia. Children scheduled undergo elective anesthesia were divided into preschool (age: 3-6 years) school-age (6-12 groups. The timer was started after intravenous administered; thereafter, injected intravenously. placed 3 min finished. If a positive response LMA insertion, such as...
Porcine reproductive and respiratory syndrome virus (PRRSV) is a highly contagious that poses significant threat to the global pig farming industry, resulting in substantial economic losses. However, owing high variability of PRRSV unclear mechanisms infection, there are currently no effective vaccines or drugs available for its prevention control. Our previous report revealed pathogenic (HP-PRRSV) requires FAK-PI3K-AKT signaling pathway facilitate entry into cells. In this study, we further...
The addition of Ag to the age hardenable Mg–Gd–Zr alloy system dramatically enhances early stage hardening kinetics. Using atom probe tomography (APT), Ag-rich clusters were detected in a Ag-containing immediately after solution treatment and water quenching. During subsequent isothermal ageing at 200 °C, high density basal precipitates was observed during stages ageing. These enriched with Gd, as confirmed by APT. It is posited that context quenched-in vacancies can attract Gd atoms,...