A5091466822- Diet, Metabolism, and Disease
- Birth, Development, and Health
- Diet and metabolism studies
- Metabolomics and Mass Spectrometry Studies
- Biochemical Analysis and Sensing Techniques
- Adipokines, Inflammation, and Metabolic Diseases
- Regulation of Appetite and Obesity
- Cannabis and Cannabinoid Research
- Adipose Tissue and Metabolism
- PARP inhibition in cancer therapy
- Sleep and Wakefulness Research
- Nutrition, Genetics, and Disease
Universidad San Pablo CEU
2020-2025
The present study was aimed at revealing the metabolic changes that occurred in cellular lipid pattern of acute and chronic myeloid leukaemia cells following treatment with cannabidiol (CBD). CBD is a non-psychoactive compound Cannabis sativa L., which has shown an antiproliferative action these type cancer cells. reduced cell viability initiated apoptotic necrotic processes both lines time dose-dependent manner, showing (HL-60) greater sensitivity than ones (K-562), without differences...
Abstract Diets rich in saturated fats are more detrimental to health than those containing mono‐ or unsaturated fats. Fatty acids an important source of energy, but they also relay information regarding nutritional status hypothalamic metabolic circuits and when excess can be these circuits. Astrocytes the main site central fatty acid β‐oxidation, astrocytes participate energy homeostasis, part by modulating hormonal signals reaching neurons, as well inflammatory response high‐fat diets....
Introduction: Obesity results from an interplay between genetic predisposition and environmental factors such as diet, physical activity, culture, socioeconomic status. Personalized treatments for obesity would be optimal, thus necessitating the identification of individual characteristics to improve effectiveness therapies. For example, impairment leptin-melanocortin pathway can result in rare cases severe early-onset obesity. Metabolomics has potential distinguish a healthy obese status;...