Karol Jastrzębski

ORCID: 0000-0002-8651-8198
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About
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Research Areas
  • Cerebral Venous Sinus Thrombosis
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Pharmacological Effects and Toxicity Studies
  • RNA regulation and disease
  • Drug Transport and Resistance Mechanisms
  • Parkinson's Disease Mechanisms and Treatments
  • Epilepsy research and treatment
  • Lysosomal Storage Disorders Research
  • Cerebrovascular and genetic disorders
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Multiple Sclerosis Research Studies
  • Metabolism and Genetic Disorders
  • Neuroscience and Neuropharmacology Research
  • Neurosurgical Procedures and Complications
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Diet and metabolism studies
  • Autoimmune Neurological Disorders and Treatments
  • Neurological and metabolic disorders
  • Blood groups and transfusion
  • Peripheral Neuropathies and Disorders
  • Pharmacogenetics and Drug Metabolism
  • Ophthalmology and Eye Disorders
  • Glycogen Storage Diseases and Myoclonus
  • Connective Tissue Growth Factor Research
  • Renal and Vascular Pathologies

Medical University of Lodz
2013-2023

Wojewódzki Szpital Specjalistyczny Nr 2
2021-2023

Uniwersytecki Szpital Kliniczny w Opolu
2021-2023

Central Clinical Hospital
2021

Université Claude Bernard Lyon 1
2019

Centre National de la Recherche Scientifique
2019

Pitié-Salpêtrière Hospital
2019

Sorbonne Université
2019

Hospices Civils de Lyon
2019

Centralny Szpital Kliniczny
2017

Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS). Four distinct courses are known, although approximately 90 % patients diagnosed with relapsing-remitting form (RRMS). The name "multiple sclerosis" pertains to underlying pathology: presence plaques in CNS, particular periventricular region, corpus callosum, cervical spine, and cerebellum. There ongoing efforts discover biomarkers that would allow for unequivocal diagnosis, assess activity...

10.1007/s12031-014-0476-3 article EN cc-by Journal of Molecular Neuroscience 2014-12-09

<h3>Objective</h3> To perform a systematic analysis and scoring of brain MRI white matter hyperintensities (WMH) in adult-onset Krabbe disease. <h3>Methods</h3> We retrospectively collected basic clinical data the first available from patients with confirmed disease manifestations beyond 10 years age. Data were obtained our reference center for lysosomal diseases (n = 6) contacted authors published articles describing 15). T2-weighted fluid-attenuated inversion recovery images each patient...

10.1212/wnl.0000000000007943 article EN Neurology 2019-07-24

Plasma from patients with Parkinson's disease (PD) is a valuable source of information indicating altered metabolites associated the risk or progression disease. Neurotoxicity dopaminergic neurons, which triggered by aggregation α-synuclein, main pathogenic feature PD. However, growing body scientific reports indicates that metabolic changes may precede and directly contribute to neurodegeneration. Identification characterization abnormal pattern in patients' plasma are therefore crucial for...

10.3390/biomedicines10123005 article EN cc-by Biomedicines 2022-11-22

Epigenetic modifications play a key role in gene regulation and expression are involved numerous cellular processes. Due to the limited research on nucleosides Parkinson’s disease (PD), it is very important consider epigenetic factors their development of PD. The aim this study was investigate compare levels modified nucleosides, such as O-methylguanosine, N6-methyl-2′-deoxyadenosine, 1-methyladenosine, 1-methylguanine, 7-methylguanine, 3-methyladenine 7-methylguanosine urine (PD) patients...

10.3390/molecules25214959 article EN cc-by Molecules 2020-10-27

Czynnik martwicy nowotworów alfa (TNF-α) jako potencjalny osoczowy marker

10.15557/an.2014.0014 article PL cc-by-nc-nd Aktualności Neurologiczne 2014-07-30

10.15557/an.2017.0011 article EN cc-by-nc-nd Aktualności Neurologiczne 2017-08-31

10.15557/an.2017.0024 article DA cc-by-nc-nd Aktualności Neurologiczne 2017-12-29

Stiff-person syndrome (SPS) is a rare disorder with an estimated prevalence in the general population of 1–2 cases/1,000,000. It 2–3 times more common females, symptom onset at age 20–50 years most cases. Although stiff-person associated antibodies against glutamic acid decarboxylase and amphiphysin, their presence not necessary for diagnosis. The treatment should be multidirectional include immunomodulation, symptomatic as well monitoring overlapping autoimmune, surgery. We present case...

10.15557/an.2021.0007 article EN cc-by-nc-nd Aktualności Neurologiczne 2021-10-27

StreszczenieZespół Melkerssona-Rosenthala jest klasycznie definiowany jako triada objawów pod postacią nawracającego obwodowego porażenia nerwu twarzowego, obrzęku w obrębie twarzy oraz języka pofałdowanego.Etiologia choroby nie została jednoznacznie potwierdzona -

10.15557/an.2014.0015 article PL cc-by-nc-nd Aktualności Neurologiczne 2014-07-30
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