A5035629887- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Crystallography and molecular interactions
- Magnetism in coordination complexes
- Metal complexes synthesis and properties
- Metal-Organic Frameworks: Synthesis and Applications
- Crystal structures of chemical compounds
- Lanthanide and Transition Metal Complexes
- Crystal Structures and Properties
- Organometallic Compounds Synthesis and Characterization
- Solid-state spectroscopy and crystallography
- Chemical Thermodynamics and Molecular Structure
- Metal-Catalyzed Oxygenation Mechanisms
- Bioactive Compounds and Antitumor Agents
- Advanced Condensed Matter Physics
- Synthesis and biological activity
- Porphyrin and Phthalocyanine Chemistry
- Inorganic Chemistry and Materials
- Organometallic Complex Synthesis and Catalysis
- Synthesis and Characterization of Heterocyclic Compounds
- Organic and Molecular Conductors Research
- Electron Spin Resonance Studies
- Marine Sponges and Natural Products
- Synthesis and Biological Evaluation
- Nuclear materials and radiation effects
University of Lisbon
2025
Hospital de Santa Maria
2022-2025
Universidade Federal de Minas Gerais
2015-2024
Centro Hospitalar Lisboa Norte
2022-2024
Universidad ICEL
2020
Instituto de Investigaciones en Ciencias de la Salud
2015-2019
Centro Universitário de Belo Horizonte
2019
Universidade Regional de Blumenau
2016
Universidade Federal Fluminense
2006-2015
Institut de Ciència de Materials de Barcelona
2011
Abstract Three tin(IV) complexes of 2‐benzoylpyridine N (4)‐phenylthiosemicarbazone (H2Bz4Ph) were prepared: [Sn(L)Cl 3 ] (1), [BuSn(L)Cl 2 (2) and [(Bu) Sn(L)Cl] (3), in which L stands for the anionic ligand formed upon complexation with deprotonation release HCl. The characterized by a number spectroscopic techniques. crystal structures H2Bz4Ph complex determined. antifungal activity its was tested against Candida albicans . thiosemicarbazone proved to be more active than complexes....
Nasal reconstruction aims to restore both function and aesthetic integrity, with the nose being central facial harmony. The paramedian forehead flap (PFF) is a cornerstone of nasal due its reliable vascular supply excellent tissue match. Managing PFF donor area, especially for larger defects, presents challenges, secondary intention healing skin grafting common approaches. A 72-year-old male underwent after basal cell carcinoma excision. flap's area was managed graft. Years later, patient...
Dimerization of lawsone occurs upon reaction with Co(BF(4))(2)·6H(2)O and N,N'-bis(pyridin-2-ylmethyl)ethylenediamine (py(2)en) to produce the mononuclear complex [Co(III)(bhnq)(py(2)en)]BF(4)·H(2)O (1). This has been investigated as a prototype bioreductive prodrug, where bhnq(2-) ligand acts model for cytotoxic naphthoquinones. Cyclic voltammetry data in aqueous solution have shown quasi-reversible Co(III)/Co(II) process at E(1/2) = -0.26 V vs Fc/Fc(+). Reactivity studies revealed...
Eight different coordination polymers (CPs) of Co2+ and Zn2+ ions with rigid polycarboxylate ligands (fumaric acid (fum) 2,5-dihydroxyterephalic (dhbdc)) have been synthesized using the same solvents, stoichiometry, counterion but two synthetic methods: liquid–liquid diffusion method–method A pH control B. The synthesis method resulted in four novel CPs: trans-Co(dmso)2(H2O)2(fum)]n (1), [trans-Zn(dmso)2(H2O)2(fum)]n (2), trans-Co(dmso)2(H2O)2(dhbdc)]n (3), [trans-Zn(dmso)2(H2O)2(dhbdc)]n...
A series of novel Mannich bases (HL1-HL13) derived from 2-hydroxy-1,4-naphthoquinone (lawsone), substituted benzaldehydes [C6H2R¹R²R³C(O)H] and various primary amines (NH2R4, R4 = n-butyl, benzyl, allyl, 2-furfuryl), their Cu2+ complexes, [Cu(L1)2]-[Cu(L13)2], have been synthesized fully characterized by analytical spectroscopic methods. The structures complexes 1(R¹ R² R³ H; Bu), 2(R¹ NO2; R4= Bu) 7 (R¹ OH; were determined single crystal X-ray diffraction studies. All crystallize in...
A unique bistable copper-metallacyclic complex is used as an elegant molecular switch for the reversible formation of emulsions by simple pH variation. This may have several exciting applications in biphasic processes such catalysis and separation science technologies.
We herein present the synthesis and X-ray structures of five copper(II) complexes formulae [Cu(bpca)(CF3SO3)(H2O)]·H2O (1), [Cu(bpca)(Phpr)(H2O)]·3/2H2O (2), {[Cu(bpca)]2[Cu(opba)(H2O)]}·H2O (3), {[Cu(bpca)]2(H2opba)}2·6H2O (4) [Cu(bpca)(EtH2opba)]n (5), where bpca = bis(2-pyridylcarbonyl)amidate, Phpr 3-phenylpropionate, CF3SO3(−) triflate (anion trifluoromethanesulphonic acid), H4opba N,N′-1,2-phenylenebis(oxamic EtH3opba monoethyl ester derivative H4opba. 1 2 are mononuclear copper atom...
Three novel cobalt(iii)-triazole complexes with structural and redox properties suitable for hypoxia-activated drug delivery were obtained. A major influence of the ancillary ligands (TPA, py2en, py2enMe2) on electronic reactivity their was observed. An [O2]-dependent reduction to cobalt(ii) by ascorbic acid provided evidence hypoxic selectivity.
This contribution shows the first monocoordinated oxamate complexes driven by crystal engineering and hydrogen bonds, featuring distinct coordination polymers their magnetic properties.
The synthesis, crystal structure and magnetic properties of an oxamate-containing erbium(III) complex, namely, tetrabutylammonium aqua[ N -(2,4,6-trimethylphenyl)oxamato]erbium(III)–dimethyl sulfoxide–water (1/3/1.5), (C 16 H 36 N)[Er(C 11 12 NO 3 ) 4 (H 2 O)]·3C 6 OS·1.5H O or n -Bu N[Er(Htmpa) O)]·3DMSO·1.5H ( 1 ), are reported. reveals the occurrence ion, which is surrounded by four -phenyl-substituted oxamate ligands one water molecule in a nine-coordinated environment, together with...
Developing and investigating advanced multifunctional materials with magnetic properties as candidates for assembling spin qubits quantum computing is imperative. A new polytopic ligand based on oxamate aniline was used to promote the synthesis of three neutral homometallic lanthanide-coordinated polymers. New complexes formula {Ln(phox)
Bi-stable molecular systems presenting valence tautomerism are associated with the development of new functional materials, which can be used for applications in organic electric conductors, optoelectronic and magnetic devices. The properties these materials adjusted slight chemical changes induced by external stimuli. Typical examples tautomer compounds coordination complexes Co o-dioxolene ligands, notably quinone like ones. In search a class cobalt we report herein synthesis...
A novel series of copper(II) coordination polymers [Cu2(O2CC8H9)4(pyz)]n (1), [Cu2(O2CC8H9)4(dps)]n (2), {[Cu(O2CC8H9)2(dps)(H2O)]·H2O}n (3), {[NaCu(O2CC8H9)2(bpm)(NO3)]·H2O}n (4), and [Cu4(O2CC8H9)6(OH)2(bpp)2]n (5) [O2CC8H9− = 3-phenylpropionate anion, pyz pyrazine, dps di(4-pyridyl)sulfide, bpm 2,2′-bipyrimidine, bpp 1,3-bis(4-pyridyl)propane] have been synthesized magneto-structurally investigated. Compounds 1 2 belong to a large group carboxylates where bis-monodentate (1) (2) ligands...
The ludwigite ${\text{Co}}_{5}\text{Sn}({\mathrm{O}}_{2}{\text{BO}}_{3}{)}_{2}$ was studied using x-ray diffraction, M\"ossbauer spectroscopy, and magnetic thermodynamic measurements. This material belongs to a family of oxyborates which presents low-dimensional subunits in the form three-leg ladders its structure. confer these materials strong anisotropy their exchange interactions that provide ludwigites several interesting properties, from partial ordering spin-glass states. Despite being...
Complexes [Ag(H2BzPh)NO3] (1), [Ag(H2BzpCH3Ph)NO3] (2), [Ag(H2BzpClPh)NO3] (3), and [Ag(H2BzpNO2Ph)NO3] (4) were synthesized with 2-benzoylpyridine benzoylhydrazone (H2BzPh) its para-methyl-benzoylhydrazone (H2BzpCH3Ph), para-chloro-benzoylhydrazone (H2BzpClPh), para-nitro-benzoylhydrazone (H2BzpNO2Ph) derivatives. Experimental data indicate that the nitrate ligand binds more strongly to silver center through one of oxygen atoms, whereas second atom from hydrazone makes much weaker...
Nevirapine (C15H14N4O) is a lipophilic drug of low aqueous solubility used in AIDS treatment. Three different crystal forms this non-nucleoside reverse transcriptase inhibitor were obtained after recrystallization procedures. Physical characterization was evaluated with DSC, TG, IR spectroscopy, and X-ray diffraction methods. Two new pseudopolymorphs have been characterized: nevirapine hemihydrate hemiethyl acetate. The pseudopolymorph identified as the acetate disordered. It converted to...
The first examples of platinum(II) complexes 3-(aminomethyl)naphthoquinone Mannich bases have been synthesised and their crystal structures are described. Neutral charged obtained, fully characterised cytotoxic activities also investigated. 3-[(R1-amino)(pyridin-2-yl)methyl]-2-hydroxy-1,4-naphthoquinones (R1 = n-Bu, HL1; Bn, HL2; furfuryl, HL3; n-heptyl, HL4 n-decyl, HL5) coordinate to through the two nitrogen atoms. neutral cis-[Pt(HL)Cl2] 1a–5a analogous cisplatin with bidentate ligand HL...
A new compound of formula (Bu4N)2[Mn2{Cu(opba)}2ox] (1) [Bu4N(+) = tetra-n-butylammonium cation, H4opba 1,2-phenylenebis(oxamic acid), and H2ox oxalic acid] has been synthesized magneto-structurally investigated. The reaction manganese(II) acetate, [Cu(opba)](2-), ox(2-) in dimethyl sulfoxide yielded single crystals 1. structure 1 consists heterobimetallic oxamato-bridged Cu(II)Mn(II) chains which are connected through bis-bidentate oxalate coordinated to the ions afford anionic layers...