A5056370623- Metal complexes synthesis and properties
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Metal-Catalyzed Oxygenation Mechanisms
- Magnetism in coordination complexes
- Metal-Organic Frameworks: Synthesis and Applications
- Porphyrin and Phthalocyanine Chemistry
- Synthesis and Characterization of Heterocyclic Compounds
- Ferrocene Chemistry and Applications
- Crystal structures of chemical compounds
- Oxidative Organic Chemistry Reactions
- Porphyrin Metabolism and Disorders
- Nanoplatforms for cancer theranostics
- Inorganic and Organometallic Chemistry
- Cancer, Hypoxia, and Metabolism
- Crystallography and molecular interactions
- Vanadium and Halogenation Chemistry
- Lanthanide and Transition Metal Complexes
- Microbial metabolism and enzyme function
- Ammonia Synthesis and Nitrogen Reduction
- Enzyme Catalysis and Immobilization
- Trace Elements in Health
- Phytase and its Applications
- Cancer and biochemical research
- Electrochemical Analysis and Applications
Universidade Federal do Rio de Janeiro
2006-2023
Universidade Federal de Santa Catarina
2001-2009
Technical University of Darmstadt
2008
University of Michigan
2005-2008
New College of Florida
2008
Universidade Federal de São Carlos
2003-2005
Universidade Federal do Paraná
2003-2005
Universidade de São Paulo
2004-2005
The tridentate Schiff base [(2-(imidazol-4-yl)ethyl)(1-methylimidazol-2-yl)methyl)imine (HISMIMI) and its reduced form HISMIMA were synthesized characterized, as well their mononuclear cis-dihalo copper(II) complexes 1 2, respectively. In addition, the dinuclear [CuII(μ-OH)2CuII]2+ (3) (4) obtained from respectively, also isolated characterized by several physicochemical techniques, including magnetochemistry, electrochemistry, EPR UV−vis spectroscopies. crystal structures of 2 determined...
We report here two copper complexes as first functional models for lytic polysaccharide monooxygenases, mononuclear copper-containing enzymes involved in recalcitrant breakdown. These feature structural and spectroscopic properties similar to those of the enzyme. In addition, they catalyze oxidative cleavage model substrate p-nitrophenyl-β-d-glucopyranoside. More importantly, a particularly stable copper(II) hydroperoxide intermediate is detected reaction conditions.
The crystal structures and redox UV−vis/EPR spectroscopic properties of two new mononuclear copper(II) complexes, [Cu(HL1)Cl2] (1) [Cu(L1)Cl] (2), prepared through the reaction between chloride ligand 2-[(bis(pyridylmethyl)amino)methyl]-4-methyl-6-formylphenol (HL1) under distinct base conditions, are reported along with solution studies. Also, we demonstrate that these CuII complexes able to cleave unactivated peptide bonds from bovine serum albumin (BSA) thermostable enzyme Taq DNA...
Three novel cobalt(iii)-triazole complexes with structural and redox properties suitable for hypoxia-activated drug delivery were obtained. A major influence of the ancillary ligands (TPA, py2en, py2enMe2) on electronic reactivity their was observed. An [O2]-dependent reduction to cobalt(ii) by ascorbic acid provided evidence hypoxic selectivity.
Abstract The nitric oxide liberation from trans ‐[Ru(NH 3 ) 4 (L)(NO)] 3+ (where L = py, 4‐pic, isn, nic, ‐His, 4‐Clpy, imN) after one‐electron‐chemical or electrochemical reduction was investigated through spectroscopic and techniques, reaction‐product analysis quantum‐mechanic calculations. These complexes can be formally viewed as a Ru II (NO + species the site is located on NO ligand. E ° for ‐[Ru (NH (L)(NO )] / 2+ redox process ranges 0.072 V vs. NHE (nic) to −0.118 (imN). specific...
As metal ions are present in the catalytic sites of several enzymes, attention has been focused on synthesis and characterization complexes able to act as biomimetic functional structural models for these systems. In this study, a novel dinuclear NiII complex was synthesized, [Ni2(L2)(OAc)2(CH3CN)]BPh4 (2) (HL2 = 2-[N-(2-(pyridyl-2-yl)ethyl)(1-methylimidazol-2-yl)amin omethyl]-4-methyl-6-[N-(2-(imidazol-4-yl)ethyl)amino methyl]phenol), employing new unsymmetrical dinucleating ligand...
Attempting to model superoxide dismutase (SOD) enzymes, we designed two new N3O-donor ligands provide the same set of donor atoms observed in active site these enzymes: KiPr2TCMA (potassium 1,4-diisopropyl-1,4,7-triazacyclononane-N-acetate) and KBPZG N,N-bis(3,5-dimethylpyrazolylmethyl) glycinate). Five CoII complexes (1−5) were obtained characterized by X-ray crystallography, mass spectrometry, electrochemistry, magnetochemistry, UV−vis, electron paramagnetic resonance (EPR) spectroscopies....
In this work, the cleavage activity of metal complex [Cu(C21H21N3O2)(OH2)2]2+ is demonstrated to occur toward double-stranded DNA, in addition its previously described amide bond activity, thus suggesting catalytic promiscuity for complex.
A new tridentate ligand [(2-hydroxybenzyl)(2-(imidazol-2-yl)ethyl)]amine (HBHA) and its first dinuclear FeIII complex have been synthesized. The crystal structures of HBHA the [Fe2III(BHA)2(μ-OCH3)2(μ-OAc)](ClO4) (1) solved by X-ray crystallography. In cation 1, each BHA− anion is arranged in a facial mode while one acetate two methoxo groups as bridging ligands complete coordination spheres centres. ions are weakly antiferromagnetically coupled (J = −10.1 cm−1) undergo quasi-reversible...
In view of the biological and commercial interest in models for Oxalate Decarboxylases (OxDC) Oxidases (OxOx), we have synthesized characterized three new MnII complexes (1−3) employing N3O-donor amino-carboxylate ligands (TCMA, 1,4,7-triazacyclononane-N-acetic acid; KiPr2TCMA, potassium 1,4-diisopropyl-1,4,7-triazacyclononane-N-acetate; KBPZG, N,N-bis(3,5-dimethylpyrazolyl methyl)glycinate). These were by several techniques including X-ray crystallographic analysis, X-band electron...
The tridentate ligands HL1, [(2-hydroxybenzyl)(2-(imidazol-2-yl)ethyl)]amine, and HL2, [(2-hydroxybenzyl)(2-(pyridil-2-yl)ethyl]amine, were used to synthesize binuclear CuII complexes, [Cu2(L1)2]Cl2•2H2O, complex 1, [Cu2(L2)2](ClO4)2•1.5H2O, 2, in order obtain catalysts for oxidative processes. Both complexes characterized by elemental analysis, IR, UV-Vis EPR spectroscopies. In addition, they studied cyclic voltammetry potentiometric titration investigate their behavior solution. crystal...
Two novel complexes, [VO2(L)] (1) and [VO2(HLox)] (2), were synthesized characterized by IV, UV-Vis NMR spectroscopy, cyclic voltammetry, elemental analysis X-ray diffraction. The synthesis of a new ligand, H2Lox, is also described. Complexes 1 2 obtained the reaction [VO(acac)2] with ligands HL respectively. Alternatively, was in presence hydroxylamine, hydroxylamine. Crystallographic data show that complexes have similar molecular structures, which cis-dioxovanadium(V) center coordinated...
This work reports the synthesis, structural, spectroscopic and magnetic investigation of two complexes, [Co(bmimapy)(3,5-DTBCat)]PF6·H2O (1) [Co(bmimapy)(TCCat)]PF6·H2O (2), where bmimapy is an imidazolic tetradentate ancillary ligand 3,5-DTBCat TCCat are 3,5-di-tert-butyl-catecholate tetrachlorocatecholate anions, respectively. Their structures have been elucidated using single crystal X-ray diffraction, showing a pseudo-octahedral cobalt ion bound to chelating dioxolene in folded...
The reaction of Fe(ClO4)3.nH2O with N,N'-bis[(2-hydroxybenzyl)-N,N' -bis(1-methylimidazole-2-yl-methyl)]ethylenediamine (H2bbimen) affords two geometric isomers, A and B, the complex cation [Fe(bbimen)]+, which were fully characterized by IR UV-visible spectroscopies, ESI mass spectrometry, molar conductivity measurements, cyclic voltammetry, spectroelectrochemistry EPR spectroscopy. geometry one these isomers has been clearly demonstrated through X-ray crystallographic analysis. It...