Vivian P. Bastiaenen
A5081787468- Intraperitoneal and Appendiceal Malignancies
- Appendicitis Diagnosis and Management
- Colorectal Cancer Surgical Treatments
- Pancreatic and Hepatic Oncology Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Gallbladder and Bile Duct Disorders
- Hernia repair and management
- Diverticular Disease and Complications
- Colorectal Cancer Screening and Detection
- Cardiac, Anesthesia and Surgical Outcomes
- Gastric Cancer Management and Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Global Health and Surgery
- Intestinal and Peritoneal Adhesions
- COVID-19 and healthcare impacts
- Cancer Cells and Metastasis
- Nanoparticle-Based Drug Delivery
- Renal cell carcinoma treatment
- Colorectal Cancer Treatments and Studies
- Ovarian cancer diagnosis and treatment
Amsterdam University Medical Centers
2018-2022
University of Amsterdam
2018-2022
Amsterdam UMC Location University of Amsterdam
2017
A significant proportion of colorectal cancer (CRC) patients develop peritoneal metastases (PM) in the course their disease. PMs are associated with a poor quality life, morbidity and dismal disease outcome. To improve care for this patient group, better understanding molecular characteristics CRC-PM is required. Here we present comprehensive characterization cohort 52 patients. This reveals that represent distinct CRC subtype, CMS4, but can be further divided three separate categories, each...
This study aims to compare surgical outcome of transanal ileal pouch-anal anastomosis (ta-IPAA) with transabdominal minimal invasive approach in ulcerative colitis (UC), using the comprehensive complication index (CCI).Recent evolutions rectal cancer surgery led dissection rectum resulting a better exposure distal and presumed outcome. The same was introduced for patients UC, decreased invasiveness.All patients, undergoing minimally restorative proctocolectomy 1, 2, or 3 stages between...
With evolving treatment strategies aiming at prevention or early detection of metachronous peritoneal metastases (PM), identification high-risk colon cancer patients becomes increasingly important. This study aimed to evaluate differences between pT4a (peritoneal penetration) and pT4b (invasion other organs/structures) subcategories regarding risk PM oncological outcomes.From eight databases deriving from four countries, who underwent curative intent for pT4N0-2M0 primary were included....
Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based on the primary point, may be published when key planned co-primary or secondary analyses are not yet available. Trial Updates provide an opportunity to disseminate additional results from studies, in JCO elsewhere, for which point has already been reported. Whether adjuvant hyperthermic intraperitoneal chemotherapy (HIPEC) might prevent peritoneal metastases after...
Approximately 20–30% of patients with pT4 colon cancer develop metachronous peritoneal metastases (PM). Due to restricted accuracy imaging modalities and absence early symptoms, PM are often detected at a stage in which only quarter eligible for curative intent treatment. Preliminary findings the COLOPEC trial (NCT02231086) revealed that were already during surgical re-exploration within two months after primary resection 9% cancer. Therefore, second look diagnostic laparoscopy (DLS) detect...
There is ongoing debate concerning the necessity of routine histopathological examination following cholecystectomy. In order to reduce pathology workload and save costs, a selective approach has been suggested, but evidence regarding its oncological safety lacking.In this multicentre, prospective, cross-sectional study, all gallbladders removed for gallstone disease or cholecystitis were systematically examined by surgeon macroscopic abnormalities indicative malignancy. Before sending...
This study investigated the impact of laparoscopic or open resection locally advanced colonic cancer on incidence and severity adhesions evaluated by laparoscopy at 18 months, primarily intended to evaluate peritoneal recurrence. Open surgery was identified as an independent risk factor for adhesions, but not intraperitoneal chemotherapy.
Routine histopathological examination following appendicectomy and cholecystectomy has significant financial implications comprises a substantial portion of the pathologists' workload, while incidence unexpected pathology is low. The aim selective Following AppeNdicectomy CholecystectomY (FANCY) study to investigate oncological safety potential cost savings based on macroscopic assessment performed by surgeon. This Dutch multicentre prospective observational study, in which removed...
Objective: To investigate the oncological safety and potential cost savings of selective histopathological examination after appendectomy. Background: The necessity routine appendectomy has been questioned, but prospective studies investigating a policy are lacking. Methods: In this multicenter, prospective, cross-sectional study, inspection palpation (meso)appendix was performed by surgeon in patients with suspected appendicitis. surgeon's opinion on additional value reported before sending...
It was hypothesized that colon cancer with only retroperitoneal invasion is associated a low risk of peritoneal dissemination. This study aimed to compare the metachronous metastases (mPM) between intraperitoneal and invasion.In this international, multicenter cohort study, patients pT4bN0-2M0 who underwent curative surgery were categorized as having (e.g. bladder, small bowel, stomach, omentum, liver, abdominal wall) or ureter, pancreas, psoas muscle, Gerota's fascia). Primary outcome...