A5022623078- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Management of metastatic bone disease
- Meningioma and schwannoma management
- Cervical and Thoracic Myelopathy
- Scoliosis diagnosis and treatment
- Surgical Simulation and Training
- Intraoperative Neuromonitoring and Anesthetic Effects
- Vascular Malformations Diagnosis and Treatment
- CRISPR and Genetic Engineering
- Genetics, Aging, and Longevity in Model Organisms
- Bone Tumor Diagnosis and Treatments
- Pluripotent Stem Cells Research
- Bone health and osteoporosis research
Neurological Surgery
2022-2024
University of California, San Francisco
2022-2024
University of California, Berkeley
2023
University of San Francisco
2022
Abstract Mutations in the BRCA2 gene are associated with sporadic and familial cancer, cause genomic instability sensitize cancer cells to inhibition by poly(ADP-ribose) polymerase (PARP). Here we show that human pluripotent stem (hPSCs) one copy of deleted can be used annotate variants this test their sensitivities PARP inhibition. By using Cas9 edit functional allele locally haploid hPSCs fibroblasts differentiated from them, characterized essential regions identify permissive...
Quantitative metrics of the dural sac such as cross-sectional area are commonly used to evaluate central canal stenosis. The aim this study was analyze 2 new measure spinal stenosis on basis ratio between and disc areas (DDRCA) anterior-posterior diameters (DDRDIA) compare them with established quantitative sac.T2-weighted axial MR images (n = 260 patients) were retrospectively evaluated, graded for normal (no stenosis), mild, moderate, or severe from L1/L2 through L5/S1 1 grade per level...
In the absence of spinal cord compression, it is unclear if surgery more effective than radiation treatment for improving functional outcomes in metastatic tumor patients with potentially unstable spines. The authors compared status assessed Karnofsky Performance Status (KPS) and Eastern Cooperative Oncology Group (ECOG) scores after or without compression Spine Instability Neoplastic Score (SINS) values 7-12 indicating possible instability (SINS 7-12).A retrospective review was performed...
Tawil, Michael E. BS*; Chryssikos, Timothy MD, PhD*; Rechav Ben-Natan, Alma BA*; Ambati, Vardhaan S. MS*; Guney, Ekin MD‡; Shah, Vinil MD§; Abla, Adib A. MD*; Mummaneni, Praveen V. MBA* Author Information
The development of the 3D exoscope has advanced intraoperative visualization by providing access to visual corridors that were previously difficult obtain or maintain with traditional operating microscopes. Favorable ergonomics, maneuverability, and increased potential for instruction provide utility in a large range procedures. Here, authors demonstrate system patient progressive thoracolumbar junctional kyphosis bony retropulsion T12-L1 fracture requiring Schwab grade 5 osteotomy fusion....
Shabani, Saman MD; Agarwal, Nitin Ben-Natan, Alma Rechav BA; Huang, Jeremy BS; Le, Vivian P. MPH; Chou, Dean Mummaneni, Praveen V. MD, MBA Author Information