A5017002500- Hepatocellular Carcinoma Treatment and Prognosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Colorectal Cancer Surgical Treatments
- Anorectal Disease Treatments and Outcomes
- Organ Transplantation Techniques and Outcomes
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Treatments and Studies
- Metastasis and carcinoma case studies
- Diverticular Disease and Complications
- Gallbladder and Bile Duct Disorders
- Pancreatic and Hepatic Oncology Research
- Pelvic floor disorders treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Esophageal and GI Pathology
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Genetic and Kidney Cyst Diseases
- Lung Cancer Treatments and Mutations
- Appendicitis Diagnosis and Management
- Autonomous Vehicle Technology and Safety
- Hernia repair and management
- Colorectal and Anal Carcinomas
- Cancer Genomics and Diagnostics
- Reconstructive Surgery and Microvascular Techniques
- Lung Cancer Research Studies
Jena University Hospital
2016-2025
Klinikum Magdeburg
2011-2025
Friedrich Schiller University Jena
2013-2025
University of Zurich
2017
Creative Research Enterprises (United States)
2016
BMW (Germany)
2010-2012
BMW Group (Germany)
2012
The prevalence of obesity is increasing at an alarming rate in industrialized countries. Obesity a systemic disease that causes not only macroscopic alterations, but also mitochondrial dysfunction. Laparoscopic sleeve gastrectomy (LSG) poses potential therapeutic option for patients with severe obesity. In order to ascertain the efficacy bariatric interventions, it important assess weight loss, changes body composition. Additionally, aim this study was investigate association between loss...
A system, particularly a decision-making concept, that facilitates highly automated driving on freeways in real traffic is presented. The system capable of conducting fully lane change (LC) maneuvers with no need for driver approval. Due to the application traffic, robust functionality and general safety all participants are among main requirements. Regarding these requirements, consideration measurement uncertainties demonstrates major challenge. For this reason, integrated probabilistic...
Background and aims: The therapeutic management of fistulas presents significant challenges, often involving both conservative surgical approaches. Despite these interventions, recurrence postoperative mortality rates remain high. Endoscopic stent insertion into the fistula, along with creation a stoma, may offer promising alternative for patients who fail or therapies. This study aimed to evaluate feasibility, effectiveness, safety endoscopic in treatment refractory small intestinal...
In der aktuellen AWMF-S3-Leitlinie wird unter anderen plastischen Verfahren die Limberg-Plastik zur Behandlung Pilonidalsinuserkrankung empfohlen. Arbeit sollen Langzeitergebnisse Pilotstudie "Ergebnisse eines zweizeitigen Verfahrens mit primärer Exzision und im Intervall Therapie einer sakrokokzygealen Pilonidalsinuserkrankung" dargestellt werden, 2015 publiziert wurde. Im Zeitraum von 2010 bis 2013 wurden 50 Patienten behandelt. Nach initialer wurde den eine plastische Deckung nach...
Abstract The aim of the present retrospective single centre study was to define changes in microbiological flora recurring sacrococcygeal pilonidal sinus ( PS ). Microbiological findings swab samples abscess‐forming from 2000 2010 were evaluated. Within this time span, 73 taken primary pPS ) and 23 patients with rPS Our results show a statistically significant shift bacterial towards gram‐positive range P = 0·029) tendency aerobic 0·090). Pathogens are not always solely anaerobic or...
Abstract Background It has been shown that local ablative procedures enable downsizing, reduce drop-out from the waiting list and improve prognosis after liver transplantation. is still unclear whether a response to therapy due favorable tumor biology or if real benefit in stabilization exists, particularly complete pathological response. Method Data of 163 HCC patients who underwent transplantation were extracted our prospectively maintained registry. We analyzed load, pre-transplant...
Background . Intestinal fatty acid-binding protein (I-FABP) has been shown to be of high diagnostic value in patients with acute mesenteric ischemia. Whether these results can reproduced critically ill on the ICU was investigated. Materials and Methods I-FABP measured serum urine 43 when ischemia suspected. Bowel confirmed 21 (group 1). 22 who survived at least seven days without confirmation were assigned group 2. levels compared between groups, interval from event that triggered...
Perihilar cholangiocarcinoma (Klatskin tumor) is a rare tumor entity, which diagnosed late due to uncharacteristic symptoms. The therapeutic strategy for cure still liver resection. Liver transplant in cases of locally irresectable tumors represents an alternative potential curative therapy select group patients.We present our data 22 patients with Klatskin who received transplants between 1996 and 2015. We analyzed relevant prognostic factors the selection be transplanted ensure acceptable...
Intrahepatic cholangiocarcinoma is in most transplant regions a contraindication for liver transplantation, even ruling out an active waiting list registration. However, recent studies showed that well-selected patients after neo-adjuvant treatment benefit from transplantation with good long-term outcomes. The role of living donor unclear this indication. current study focuses on LDLT intrahepatic cholangiocarcinoma.
Extrahepatic body fat could be a relevant factor affecting liver regeneration after partial hepatectomy. The aim of this study was to evaluate the potential role fatty tissue in capacity resection cohort living donors.
Purpose: This study aimed to elucidate the various new classifications and use of LDLT in this context for HCC beyond milan criteria.
 Methods: The clinical data patients with outside criteria who underwent LT at Jena University between Januar 2007 August 2023 were retrospectively analyzed. Eligible classified according classification systems. Clinicopathological features, overall- disease-free survival rates compared two groups (LT vs. LDLT) bridging therapy. 
 Results: Among 245...
Purpose: This study was designed to elucidate the various new classifications and use of LDLT bridging therapy for HCC in this context beyond Milan criteria (MC). Methods: The clinical data patients with outside MC who underwent LT at Jena University between January 2007 August 2023 were retrospectively analysed. Eligible classified according classification systems. Clinicopathological features, overall disease-free survival rates compared within therapy. Results: Among 245 analysed, 120 did...
In 1948, the Russian maxillofacial surgeon Alexander A. Limberg published his monograph “Mathematical Principles of Local Plastic Procedures on Surface Human Body,” in which he described flap plasty techniques for coverage rhombus-shaped defects.1 This work was Russian. 1966, a description mathematical principles flaps defects first time English “Design Flaps” chapter book Modern Trends Surgery.2 defect using paper model. this model, opposite angles are 60 degree and 120 degrees, lengths all...