A5052227662- Long-Term Effects of COVID-19
- Adolescent and Pediatric Healthcare
- Kawasaki Disease and Coronary Complications
- Autoimmune and Inflammatory Disorders Research
- Growth Hormone and Insulin-like Growth Factors
- Genomic variations and chromosomal abnormalities
- Asthma and respiratory diseases
- Biochemical Analysis and Sensing Techniques
- Eosinophilic Esophagitis
- Bacterial Infections and Vaccines
- Acute Lymphoblastic Leukemia research
- Lung Cancer Diagnosis and Treatment
- Ultrasound in Clinical Applications
- Genetics and Neurodevelopmental Disorders
- Olfactory and Sensory Function Studies
- Immune Cell Function and Interaction
- Genetic Syndromes and Imprinting
- Childhood Cancer Survivors' Quality of Life
- Radiology practices and education
- Inflammatory Bowel Disease
- Digestive system and related health
- IL-33, ST2, and ILC Pathways
- Sensory Analysis and Statistical Methods
- Genomics and Rare Diseases
Azienda Ospedaliera Universitaria Senese
2024-2025
University of Siena
2024-2025
Ospedale dei Bambini Vittore Buzzi
2021-2025
University of Milan
2019-2024
Background/Objectives: ZNF711(Zinc finger protein 711) encodes a zinc of currently undefined function, located on the X chromosome. Current knowledge includes limited number case reports where this gene has been exclusively associated with X-linked intellectual disability (XLID). As far as we are aware, report first cases epilepsy particular variant. Our aim is to further delineate phenotypic spectrum ZNF711 pathogenic variants, adding clinical features rare condition, following...
Abstract Objectives Potential coeliac disease (PCD) is defined by the presence of positive CD-specific autoantibodies with a normal/extremely mildly damaged intestinal mucosa. This study sought to examine progression PCD in children maintaining gluten-containing diet and identify risk factors associated onset CD. A comparative literature review was conducted assess results context existing evidence. Methods retrospective cohort performed on 67 diagnosed between January 2005 2022, maximum...
Inflammatory bowel diseases (IBDs) including Crohn's disease (CD), ulcerative colitis (UC) and inflammatory unclassified (IBD-U) are chronic disorders which can affect the gastrointestinal tract. Anti-tumor necrosis factors antibodies (anti-TNFα) such as infliximab (IFX) adalimumab (ADA) first line biological therapy for severe or complicated IBDs in pediatric age. Second therapeutic options vedolizumab (VDZ) ustekinumab (UST) currently used off-label Furthermore, despite optimization of...
To describe neurological involvement in multisystem inflammatory syndrome children (MIS-C) and to evaluate whether manifestations are related the degree of multiorgan inflammation.The authors conducted a retrospective analysis clinical, electroencephalographic (EEG), neuroradiological (MRI), CSF parameters 62 with MIS-C (45 M, age 8 months-17 years, mean 9 years) hospitalized between October 1, 2020 March 31, 2022.Neurological was documented 58/62 (93.5%) patients. Altered mental status...
Type 1 diabetes (T1D) is one of the most common systemic diseases in childhood which predisposes patient to serious short-term and long-term complications, affecting all body systems. Taste olfactory impairments were first described a long time ago adult patients affected by (both type 2 diabetes). However, studies evaluating taste perception, behavioral attitudes (e.g., food neophobia), preferences toward foods children adolescents T1D are globally lacking. Therefore, purpose this study was...
Background: Multisystem inflammatory syndrome is a severe complication of SARS-CoV-2 infection in children (MIS-C). To date, data on its long-term sequelae mainly concern cardiac outcomes. Methods: All ≤18 year olds consecutively admitted to the Buzzi Children’s Hospital with diagnosis MIS-C between October 1, 2020, and May 31, 2022 were followed up for 12 months by dedicated multidisciplinary team. They underwent laboratory tests, multi-organ clinical instrumental assessments, psychosocial...
A 2.5-year-old girl was evaluated for poor growth. Despite low IGF-1 levels, GH deficiency excluded. Further investigation revealed celiac disease, diagnosed via EGDS. After starting a gluten-free diet, catch-up growth observed. The patient remained under follow-up to monitor her progress.
<b>Introduction:</b> Pneumonia is a common pediatric disease leading to emergency department access (ED). Despite the presence of international guidelines, diagnostic approaches vary on bases expertise and resources. Prescription chest radiography (CR) although American Academy Pediatrics advise use it only in case recurrence or suspected complications. Children undergoing CR are more likely be discharged with antibiotics little impact secondary access. <b>Aims Objectives:</b> We wanted...