- Inflammatory Bowel Disease
- Microscopic Colitis
- Clinical Nutrition and Gastroenterology
- Liver Diseases and Immunity
- Child Nutrition and Feeding Issues
- Gut microbiota and health
- Clostridium difficile and Clostridium perfringens research
- Celiac Disease Research and Management
- Eosinophilic Esophagitis
- Immunodeficiency and Autoimmune Disorders
- Viral gastroenteritis research and epidemiology
- Pediatric Hepatobiliary Diseases and Treatments
- Probiotics and Fermented Foods
- Helicobacter pylori-related gastroenterology studies
- Pregnancy and Medication Impact
- Folate and B Vitamins Research
- Adolescent and Pediatric Healthcare
- Digestive system and related health
- Diet and metabolism studies
- Antibiotic Resistance in Bacteria
- Obesity, Physical Activity, Diet
- Migraine and Headache Studies
- Intestinal Malrotation and Obstruction Disorders
- Gastrointestinal motility and disorders
- Child and Adolescent Health
Bambino Gesù Children's Hospital
2014-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2014-2024
University of Messina
2010-2018
Boston Children's Hospital
2015
The ketogenic diet is known to be a possible adjuvant treatment in several medical conditions, such as patients with severe or drug-resistant forms of epilepsy. Its use has recently been increasing among adolescents and young adults due its supposed weight-loss effect, mediated by lipolysis lowered insulin levels. However, there are still no precise indications on the diets pediatric age for weight loss. This approach also proposed other types disorder inherited metabolic disorders,...
Primary sclerosing cholangitis (PSC) is a chronic, fibroinflammatory, cholestatic liver disease of unknown etiopathogenesis, often associated with inflammatory bowel diseases. Recent evidence ascribes, together immunologic and environmental components, significant role to the intestinal microbiota or its molecules in PSC pathogenesis.
Study on 88 adolescents with severe obesity (BMI >99°pc WHO), median age 12 ± 2 yrs, F 45%, of which 57 treated Therapeutic Education and 31 Dietotherapy. At T0: BMI 30.2 5, z score 2.98 0,4. Grade excess weight after 2.5 1.3 years in the two groups. [Tanas R Congresso Nazionale Società Italiana di Medicina dell’Adolescenza, Palermo 2012]
Malnutrition is frequent in neurologically impaired (NI) children. Enteral feeding via gastrostomy tube increasingly being used to provide adequate nutrition. Our aim was assess the outcomes of exclusive with standard polymeric formula children NI, severe oro-motor dysfunction, and malnutrition, investigate role underlying NI-associated disease. A five-year retrospective study from January 2013 November 2017 conducted. The primary nutritional malnourished NI secondary complications impact...
Autoimmune liver disease is reported in up to 7.8% of children with inflammatory bowel disease. A distinct phenotype has been suggested adults and small pediatric cohorts. The aim the study was evaluate features associated autoimmune diseases analyze characteristics disease.Information on patients obtained from Italian Pediatric Inflammatory Bowel Disease Registry. Data without were compared.Autoimmune detected 6.8% 677 enrolled significantly diagnosis ulcerative colitis (83%), pancolonic...
Introduction: The incidence of inflammatory bowel disease (IBD) has increased over the last 50 years. It is now recognized that several genetic defects can express an IBD-like phenotype at very early onset (<6 years).Areas covered: aim this review was to update knowledge concerning specificity IBD <6 years, which include conventional/standard as well monogenic diseases.Expert commentary: We found females are less prone than males develop disorders, have X-linked heritability in cases....
Background/Objectives: In Italy, the prevalence of celiac disease (CeD) among children exceeds 1.5% and has steadily increased with a linear trend over past 25 years. The clinical presentation is heterogenous change in onset symptoms been described recent aim study to describe pattern CeD during last 12 years single Italian center. Methods: We retrospectively enrolled all diagnosed at Bambino Gesù Children Hospital, Rome between 1 March 2011 22 June 2023. To investigate changes presentation,...
Gastroesophageal Reflux (GER) is a common condition in childhood characterized by the rise of gastric contents into esophagus. According to International Consensus Montreal, gastroesophageal reflux disease (GERD) defined as that develops when retrograde passage causes troublesome symptoms and/or complications result an impairment quality life these patients [1]. In pediatric population, there are conditions at risk developing GERD, like neurological impairment, history esophageal atresia...
Colonization by multidrug-resistant (MDR) organisms in liver transplant (LT) candidates significantly affects the LT outcome. To date, consensus about patient management is lacking, including microbiological screening indications. This pilot study aimed to evaluate impact of carbapenem-resistant Klebsiella pneumoniae (CR-KP) colonization paediatric enable optimal prevention and therapeutic strategies that exploit both clinical approaches. Seven patients colonized CR-KP were evaluated before...
The increase of microorganisms multi-drug resistant (MDR) to antibiotics (ATBs) is becoming a global emergency, especially in frail subjects. In chronic liver disease (LD) with indications for transplantation (LT), MDR colonization can significantly affect the LT outcome. However, no clear guidelines microbial management are available. A novel approach toward MDR-colonized patients undergoing was developed at our Center refraining from ATBs use during transplant waiting list, and an...
Adult patients with both inflammatory bowel disease (IBD) and celiac (CeD) have peculiar phenotypic features. This study aimed at describing the characteristics natural history of children IBD CeD.This was a case-control based on national registry. Cases included diagnosed CeD. Two matched controls without CeD, 2 CeD were selected for each case. Inflammatory phenotype history, comprising growth pubertal development, compared between groups.Forty-nine (1.75%) identified out 2800 IBD. Compared...
We report a case of 3-year-old North African child, initially assessed for nonspecific urinary symptoms such as haematuria and burning urination. The ultrasound evaluation showed vegetating mass occupying the lumen with weak vascular signs at Colour-Doppler evaluation. An explorative cystoscopy was performed it revealed nonbleeding lesion, white in colour, pedunculated, projecting into lumen, associated brown satellite formation. Histological examination mixed Botryoid Spindle Cell...
KEYWORDS: Adalimumabadverse effectsadultbiological drugsinflammatory bowel diseasesinfliximablungpediatric