A5033996589- Transcranial Magnetic Stimulation Studies
- Stroke Rehabilitation and Recovery
- Thyroid Disorders and Treatments
- Muscle activation and electromyography studies
- Immune Cell Function and Interaction
- Child Abuse and Related Trauma
- Thyroid Cancer Diagnosis and Treatment
- Traumatic Ocular and Foreign Body Injuries
- Botulinum Toxin and Related Neurological Disorders
- Motor Control and Adaptation
- Restraint-Related Deaths
- Diet, Metabolism, and Disease
- Shoulder and Clavicle Injuries
- Marine and coastal plant biology
- Traumatic Brain Injury and Neurovascular Disturbances
- Diverticular Disease and Complications
- Amoebic Infections and Treatments
- Plant Gene Expression Analysis
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Marine and Coastal Ecosystems
- Enzyme Production and Characterization
- Epigenetics and DNA Methylation
- Genomic variations and chromosomal abnormalities
- Cancer-related Molecular Pathways
- Artificial Intelligence in Healthcare and Education
The University of Tokyo
2023-2025
TS Tech (Japan)
2025
National Hospital Organization Hokkaido Medical Center
2024
Osaka University
1970-2024
Iwakuni Medical Center
2023
Hokkaido University
1997-2012
Hokkaido University Hospital
2008
Tokeidai Memorial Hospital
2008
University of Miyazaki
2006
Weizmann Institute of Science
2003
A recent report has demonstrated that the contralesional primary motor cortex (M1) inhibited ipsilesional M1 via an abnormal transcallosal inhibition (TCI) in stroke patients. We studied whether a decreased excitability of induced by 1 Hz repetitive transcranial magnetic stimulation (rTMS) caused improved performance affected hand patients releasing TCI.We conducted double-blind study real versus sham rTMS After had well- performed training to minimize possibility during measurement, they...
Recent reports demonstrated that low-frequency repetitive transcranial magnetic stimulation (rTMS) over the unaffected hemisphere improved affected hand function in chronic stroke patients. We investigated whether 1 Hz rTMS motor learning of patients after stroke.A double-blind study.Twenty with subcortical stroke.The were randomly assigned to receive either a sub-threshold (1 Hz, 25 minutes) or sham stimulation, and all performed pinching task stimulation. evaluated excitatory inhibitory...
The interhemispheric competition model proposes that the functional recovery of motor deficits in patients after stroke can be achieved by increasing excitability affected hemisphere or decreasing unaffected hemisphere. We investigated whether bilateral repetitive transcranial magnetic stimulation might improve paretic hand stroke.A double-blind study.Thirty with chronic subcortical stroke.The were randomly assigned to receive 1 Hz over hemisphere, 10 comprising both and stimulation. All...
Low-frequency repetitive transcranial magnetic stimulation (rTMS) over the unaffected motor cortex may improve function of paretic hand after stroke. However, low-frequency rTMS might adversely affect bimanual movement by decreasing transcallosal function.The authors investigated whether combined administration and direct current (tDCS) prevents deterioration induced hemisphere.A total 27 participants with chronic subcortical stroke were randomly assigned to receive either 1 Hz hemisphere,...
The persistence of diagnostic errors, despite advances in medical knowledge and diagnostics, highlights the importance understanding atypical disease presentations their contribution to mortality morbidity. Artificial intelligence (AI), particularly generative pre-trained transformers like GPT-4, holds promise for improving accuracy, but requires further exploration handling presentations.
Abstract Reactions commonly used in synthetic organic chemistry are named after their discoverers or developers. They called the name reactions and generally consist of several elementary reactions. Quantum chemical calculations can optimize transition state (TS) structures The geometrical feature TS is motif. We have constructed a database (QMRDB) with motif information been continuing to accumulate them. In present study, we extracted 102 from QMRDB attempted classify them using Kohonen...
The ALL-1 gene is directly involved in 5-10% of ALLs and AMLs by fusion to other genes or through internal rearrangements. DNA microarrays were utilized determine expression profiles with These distinguish those tumors from AMLs. patterns ALL-1-associated tumors, particular ALLs, involve oncogenes, tumor suppressors, anti apoptotic genes, drug resistance etc., correlate the aggressive nature tumors. whose differentiates between without rearrangement further divided into several groups...
Thyroid storm is the most severe manifestation of thyrotoxicosis. Beta-blockers are among standard treatment regimens for this condition, with propranolol being historically preferred option. However, 2016 guidelines issued by Japan Association and Endocrine Society recommend use beta-1 selective beta-blockers over nonselective beta-blockers, such as propranolol. Nevertheless, evidence supporting recommendation limited. Herein, we aimed to investigate in-hospital mortality patients thyroid...
The mechanism of reorganization after stroke remains uncertain. Several studies that have measured reaction time (RT) delay by transcranial magnetic stimulation (TMS) revealed some substrates responsible for the motor recovery. In this study, we evaluated RT and inhibitory functions examining silent period (SP) in primary cortex (M1) premotor (PMC) affected hemisphere. Using these data, investigated whether a change system might influence recovery.This study was performed 20 patients with...
Primary objective: To study whether transcallosal inhibition (TCI) can evaluate the severity of traumatic brain injury (TBI).Research design: Case-control study.Methods and procedures: Twenty patients with a chronic TBI 20 control subjects were studied. The following transcranial magnetic stimulation parameters checked; resting motor threshold, central latency times, onset TCI, duration conduction times amount TCI. was evaluated using Glasgow Coma Scale (GCS).Main outcome results: TCI...
In clinical practice, patient assessments rely on established scales. Integrating data from these scales into the International Classification of Functioning, Disability, and Health (ICF) framework has been suggested; however, a standardized approach is lacking. Herein, we tested new to develop conversion table translating scale scores ICF Qualifiers based clinician survey. The survey queried rehabilitation professionals about which functional independence measure (FIM) item (1-7)...
Abstract Context Iodine, combined with antithyroid drugs, is recommended as an initial pharmacologic treatment for thyroid storm according to some clinical guidelines. However, the efficacy of iodine in managing remains unexplored. Objective This study aimed determine whether early potassium iodide (KI) use associated mortality patients hospitalized storm. Methods Using Japanese Diagnosis Procedure Combination database, we identified between July 2010 and March 2022. We compared in-hospital...
In clinical practice, patient assessments rely on established scales. Integrating data from these scales into the International Classification of Functioning, Disability, and Health (ICF) framework has been suggested; however, a standardized approach is lacking. Herein, we tested new to develop conversion table translating scale scores ICF qualifiers based clinician survey. The survey queried rehabilitation professionals about which functional independence measure (FIM) item (1–7)...
Takeuchi N, Toshima M, Chuma T, Matsuo Y, Ikoma K: Repetitive transcranial magnetic stimulation of the unaffected hemisphere in a patient who was forced to use affected hand. Am J Phys Med Rehabil 2008;87:74–77. We present case report 56-yr-old chronic stroke with right hemiparesis treated repetitive (rTMS) therapy. Before stroke, had suffered an accident that led paralysis and contracture left upper limb, and, subsequently, he only his limb for routine activities, despite hemiparesis....
Emphysematous cystitis is a rare type of urinary tract infection that characterized by the accumulation gas within walls and lumen bladder. In rarer instances, pneumoperitoneum may accompany emphysematous cystitis. When suspected through imaging studies in patients with cystitis, surgical abdominal exploration frequently performed considering possibility bladder perforation or coexistence intestinal perforation. We successfully managed case accompanied conservatively. A 90-year-old woman...
This report presents an autopsy case of the homicidal choking adult, who died as a result tissue paper being thrust into his mouth. An in-patient (a 29-year-old Japanese man) at mental hospital was choked to death by another male in-patient, roommate, large amount mouth after rendering him slightly unconscious cervical compression. At time discovery, this patient believed have committed suicide inserting own Autopsy findings and re-investigation revealed that subject had been murdered. is...
BACKGROUND Hemophagocytic lymphohistiocytosis (HLH) is a rare life-threatening systemic hyperinflammatory condition. Most adult HLH cases are secondary to infection, malignancy, and rheumatic diseases. Epstein-Barr virus (EBV) infection the most frequent cause of infection-induced HLH. Early treatment with dexamethasone, etoposide, cyclosporine generally recommended for patients However, this regimen was established based on pediatric clinical trial data; thus, its efficacy validity in...
Cricoid cartilage fracture is generally caused by significant neck trauma and causes continuous dyspnea, pain, or hoarseness developing immediately after the traumatic episode. A 69-year-old woman without any history of was admitted to our hospital with intermittent dyspnea. Six months before admission she had started complain dyspnea occurring several times a month warning, improving spontaneously within few hours treatment. Her primary care doctor diagnosed asthma treated inhaled...