A5006588918- Peripheral Neuropathies and Disorders
- Autoimmune Neurological Disorders and Treatments
- Innovations in Medical Education
- Infectious Diseases and Tuberculosis
- Clinical Reasoning and Diagnostic Skills
- Vasculitis and related conditions
- Myasthenia Gravis and Thymoma
- Polyomavirus and related diseases
- Multiple Myeloma Research and Treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Multiple Sclerosis Research Studies
- Infective Endocarditis Diagnosis and Management
- Osteomyelitis and Bone Disorders Research
- Systemic Lupus Erythematosus Research
- Orthopedic Infections and Treatments
- Alcoholism and Thiamine Deficiency
- Sarcoidosis and Beryllium Toxicity Research
- Mast cells and histamine
- Artificial Intelligence in Healthcare and Education
- Neurological Complications and Syndromes
- Traditional and Medicinal Uses of Annonaceae
- Educational Games and Gamification
- Salivary Gland Disorders and Functions
- Reproductive tract infections research
- Autopsy Techniques and Outcomes
University of Utah
2021-2024
Chiba University Hospital
2020-2023
Icahn School of Medicine at Mount Sinai
2023
Vanderbilt University Medical Center
2023
Aso Iizuka Hospital
2023
KU Leuven
2023
Kameda Medical Center
2023
Emory Healthcare
2023
Naval Hospital Bremerton
2023
George E. Wahlen Department of VA Medical Center
2023
It is known that obese adipose tissues are hypoxic and express hypoxia-inducible factor (HIF)-1α. Although some studies have shown the expression of HIF-1α in adipocytes induces glucose intolerance, mechanisms still not clear. In this study, we examined its effects on development type 2 diabetes by using adipocyte-specific knockout (ahKO) mice. ahKO mice showed improved tolerance compared with wild (WT) Macrophage infiltration mRNA levels monocyte chemotactic protein-1 (MCP-1) tumor necrosis...
The persistence of diagnostic errors, despite advances in medical knowledge and diagnostics, highlights the importance understanding atypical disease presentations their contribution to mortality morbidity. Artificial intelligence (AI), particularly generative pre-trained transformers like GPT-4, holds promise for improving accuracy, but requires further exploration handling presentations.
Learning point for cliniciansWe describe a case of Bell's palsy after Janssen COVID19 (Ad26.CoV2.S) vaccination.To the best our knowledge, this is first report describing an incidence injection Ad26.CoV2.S vaccination, and we highlight to further discussion review.
The gamification of learning increases student enjoyment, and motivation engagement in tasks. This study investigated the effects using decision-making cards (DMCs) on diagnostic cost case scenarios.Thirty medical students clinical clerkship participated were randomly assigned to 14 small groups 2-3 each. Decision-making was gamified DMCs with a information heading front, details back. First, each team provided brief scenarios. Subsequently, depending distributed team, members chose one at...
Background: The diagnosis and treatment of autoimmune optic neuritis (ON) has improved with the accessibility reliability aquaporin-4 (AQP4) myelin oligodendrocyte glycoprotein (MOG) antibody testing, yet autoantibody-negative ON remains common. This study describes demographic, clinical, outcome data in patients isolated across pediatric adult cohort. Methods: A retrospective chart review University Utah Health International Classification Diseases ( ICD ) code ICD-9 377.30 (ON...
The mRNA-1273 SARS-CoV-2 vaccine received emergency use authorization in December 2021. We present a case of myasthenia gravis (MG) which became clinically apparent following vaccination against SARS-CoV-2. A 30-year-old man developed acute onset diplopia, 2 days after receiving his first He reported blurred vision with horizontally displaced images, worsened increased eye strain. Diplopia resolved when one was covered. also had fatigable arm weakness, but denied dysphagia, dysarthria,...
Introduction: The C9orf72 mutation can manifest in diverse clinical ways, including rapid cognitive decline, parkinsonism, or late-life neuropsychiatric symptoms, sometimes mimicking autoimmune encephalitis. Case Report: A 64-year-old female presented to the neurology clinic with rapidly progressive dementia (RPD) associated episodes of headache, confusion, auditory hallucinations, and abnormal electroencephalogram. She was treated empirically at an outside hospital for possible encephalitis...
Despite advancements in the pedagogy of medical education various fields, Japan has no standardized English education. The U.S. Medical Licensing Examination (USMLE) Study Group Tokushima is an extracurricular activity which students and recent graduates meet every 1-2 months. aim to stimulate students' curiosity ; cultivate their initiative, self-efficacy, learning goals motivate them be self-regulated learners. Accordingly, we conducted near-peer teaching style lectures that focused on...
The study evaluated the effectiveness of near‐peer teaching in medical English education and found that it led to higher levels motivation, curiosity, initiative, self‐efficacy, learning goals, psychological safety among participants compared traditional teacher‐centered approaches. also observed behavioral changes active engagement participants. We hope our activity will inspire other educators adopt similar approaches their classes promote more effective language health professionals.
We report a case of Kelch-like protein-11 (KLHL11) encephalitis associated with squamous cell carcinoma (SCC) unknown origin in the neck.A 70-year-old man, diagnosed prurigo nodularis 4 months prior, presented subacute-onset progressive dysarthria, imbalance, and diplopia. Neurologic examination revealed horizontal downbeating nystagmus lateral gaze, dysmetria, hearing difficulties. Skin showed localized pruritus excoriated ulcerations on neck proximal upper extremities. MRI brain T2...
Thyrotoxic periodic paralysis (TPP) is a rare complication of hyperthyroidism that manifests as painless flaccid paralysis. An East Asian man in his late 20s presented to the emergency department with an acute onset quadriparesis associated hypertonia and hyperreflexia. His initial symptoms signs suggested involvement brain spinal cord; however, MRI neuroaxis was normal. serum potassium concentration low, thyroid test results were consistent hyperthyroidism. The patient diagnosed TPP Graves’...
Abstract A history of laparoscopic cholecystectomy and mobile echogenic foci identified on abdominal ultrasound may distinguish dropped gallstones complicated by abscess from other conditions that exhibit similar findings.
During clinical reasoning case conferences, a learner-centered approach using teleconferencing can create psychologically safe environment and help learners speak up. This study aims to measure the psychological safety of students who are supposed self-explain their conference participants. crossover compared effects two methods on medical students’ safety. The population comprised 4 th -5 year participating in two-week general medicine clerkship rotation, from September 2019 February 2020....
EVALI and COVID-19 share similar clinical imaging features. Assessing the vaping or e-cigarette use history conducting urine toxicology tests for high-risk patients are important with increasing cases in young adults.
Abstract Objective To describe patient clinical characteristics associated with matched oligoclonal bands (OCB). Methods A retrospective review at the University of Utah examined patients OCB from 2015 to 2020. Clinical data, diagnosis, and outcomes were collected. Patients classified either multiple sclerosis (MS), other inflammatory neurologic disorder (other‐IND), or noninflammatory (NIND). Results Of 539 identified patients, 436 (53.4% female) matched‐only, while 103 (43.7% + unique....
To assess the demographics, neurologic manifestations, comorbidities, and treatment of patients with seronegative primary Sjögren's syndrome (pSS).We conducted a retrospective chart review on pSS evaluated by neurologist at University Utah Health between January 2010 October 2018. The diagnosis was based characteristic symptoms, positive minor salivary gland biopsy according to American-European Consensus Group 2002 criteria, antibody status.Of 45 who met study 42 (93.3%) were Caucasian, 38...
Paraneoplastic neurological syndrome (PNS) mostly presents its symptoms prior to cancer treatment. We present a case of anti-Sry-like high mobility group box 1 (SOX-1) antibody-positive PNS diagnosed during the treatment small-cell lung (SCLC). A 65-year-old woman with history smoking and SCLC (T3N1M0) was hospitalized receive chemo-radiation therapy. On day 14, course complicated by left mastitis associated febrile neutropenia. Drainage performed for mastitis, cefepime initiated. The fever...
Introduction: Guillain-Barré syndrome is an immune-mediated inflammatory polyneuritis characterised by rapidly progressive flaccid paralysis. may present with posterior reversible encephalopathy or cerebral vasoconstriction in rare cases. Case description: A woman her 60s a history of follicular lymphoma presented one-week difficulty walking and thunderclap headaches. The patient was diagnosed based on neurological examination, cerebrospinal fluid analysis nerve conduction findings. Further...
Background and Purpose For the management of central nervous system (CNS) vasculitis, it is crucial to differentiate between primary secondary CNS vasculitis understand respective etiologies. We assessed etiology, characteristics, outcomes patients with vasculitis. Methods A single-center retrospective chart review was conducted at University Utah, Department Neurology, February 2011 October 2022. Results The median age 44 included diagnosis 54 years; 25.0% were men. Compared exhibits higher...
ATX-FGF14 (formerly spinocerebellar ataxia 27, OMIM #193003) is an autosomal dominant condition caused by a pathogenic variant in the fibroblast growth factor 14 (
A woman in her 20s presented with ascending weakness and paraesthesia along flu-like symptoms. Neurological examination revealed right facial numbness V2 distribution flaccidity lower extremities, a motor power of 0/5 throughout. The T4 sensory level bilaterally positive Babinski sign were noted. Brain MRI multiple bilateral T2/fluid attenuated inversion recovery hyperintense lesions central enhancement involving the trigeminal nerve. Full spine demonstrated long-segment thoracic cord...