With important social and economic consequences, spinal cord injuries (SCIs) still exist among major health problems. Although many therapeutic agents methods investigated for the treatment of acute SCI, only high dose methylprednisolone (MP) is being used currently in practice. Due to serious side effects, systemic MP administration after SCI a critical issue that mostly considered controversial. In our study, it aimed develop nanoparticle-gel combined drug delivery system localization on...

Acromegaly is a chronic disorder characterized by enhanced growth hormone (GH) secretion and elevated insulin-like factor-I (IGF-I) levels, usually caused pituitary adenomas. In this retrospective study, we reviewed our experience with endoscopic endonasal transsphenoidal surgery (EETS) in remission rates using the 2010 consensus criteria, predictors of associated complications.The authors retrospectively analyzed data from 56 acromegalic patients who underwent pure EETS. Tumors were...

Twenty-seven consecutive mushroom poisoning cases were followed up over a period of 14 days. Fourteen out 27 died liver failure. There no deaths from renal The mushrooms identified as the amatoxin-containing Lepiota species. Therapeutic measures included nasogastric lavage, charcoal, vitamin C, B, penicillin G, corticosteroids, oral streptomycin and, in case few patients, limited amounts thioctic acid. Of ten haemodialysed, nine died. Unfortunately charcoal haemoperfusion was not available....

Purpose. The aim of this study was to assess the clinical course patients with acute low back pain (LBP) throughout 12 weeks and identify prognostic factors for non-recovery in short term.

The most common benign tumor of the brain is meningiomas. Usually diagnosed between ages 40-60, they are more in women. Studies have shown a strong relationship hormones and malignancies. Although meningiomas slow-growing tumors brain, pregnancy seems to induce its growth speed. concerning hormone may explain reason why symptoms during flare. More specifically, estrogen progesterone receptor take an active role through signal transduction inducing tumor. Thus, dilemma + meningioma arises. In...

<h3>Abstract</h3> To explain the social difficulties in autism, a large amount of research has been conducted on neural correlates perception. However, this mostly used basic stimuli (e.g. eyes, faces, hands, single agent), not resembling complexity what we encounter our daily lives, and as such, situations people with autism experience in. A more complex stimulus that do come across often is also highly relevant for functioning third-party interactions. Here, investigated if individuals...

Background: Heterotopic ossification (HO), characterized by new bone formation in the periarticular regions of large joints, is frequently seen after spinal cord injury, traumatic brain burn and trauma. It a rare complication hemiplegia following stroke, with reported incidence 1% or less.Case reports: This study reports two unusual presentations HO: (1) A 56-year-old male history atrial fibrillation on warfarin developed sudden-onset left hemiplegia. Eight months event, he was diagnosed HO...

The aggressive pathophysiology of SCI contributes to the extension this devastating condition.A mechanical trauma spinal cord triggers an immediate cascade cellular and biochemical events.Secondary injury processes that take place after neurological cause cell death by glutamate-induced exitotoxicity, inflammation, overproduction free oxygen radicals, mitochondrial dysfunction, energy failure apoptosis.Asiatic acid (AA) is a form triterpenoid, which isolated from Centella asiatica.It has...

Failed Back Syndrome (FBS) is unacceptable relief of pain or recurrence symptoms in patients after spinal surgery, such as laminectomy. One possible cause FBS peridural fibrosis (PF). PF the overproduction scar tissue adjacent to dura mater. Bleeding can Ostene an alkylene oxide copolymer material used stop bleeding from bony surfaces. Floseal a gelatin thrombin matrix sealant assist fibrin formation and promote coagulation.Total 32 female Sprague-Dawley rats were evenly allotted 4...

Cranial firearm injuries (CFAI) are associated with significant morbidity and mortality.This study was aimed to determine the factors affecting mortality of CFAI cases managed in our institution by a retrospective analysis CT scans clinical data.This multicenter examined two hundred nineteen patients presenting neurosurgery clinics after between January 2012 November 2014. Age, sex, Glasgow Coma Score (GCS), findings, rates were analyzed mortality.Mean age population 24.19±12.25 years, 85.8%...

In this research, the effect of tadalafil, a selective inhibitor cyclic guanosine monophosphate-specific phosphodiesterase type 5, on rats with spinal trauma was evaluated. The evaluation consisted neurological examination and biochemical parameters. Twenty healthy male Wistar albino were used in study. They separated into three groups: tadalafil-receiving (TD) group (n=7), laminectomy (LT) just (n=6). TD received daily dose tadalafil (10 mg/kg) for week along bait water. Each rat's cord...

Object. The authors conducted a study to determine the effectiveness of mitomycin C (MMC) in preventing epidural fibrosis rats which underwent craniectomy.Methods. Craniectomies were performed right frontoparietal region; after procedure animals had been divided 2 groups 10 each. Cotton pads soaked with 0.1 mg/ml MMC or saline (control) applied operative sites. Four weeks craniectomy sacrificed, and was evaluated histologically. dura mater thickness, density fibrosis, arachnoidal...

and prolonged mechanical pressure causes changes in the myelin sheath (28).Changes intraneural microcirculation, impairment of axonal transport alterations vascular permeability have been detected.All these cause edema formation signal conduction (26).The objective treatment is to relieve imposed on median nerve.To this end, many conservative AIm: To investigate effectiveness local steroid injection surgical decompression patients with severe carpal tunnel syndrome (CTS) also compare...

Leptomeningeal adhesions and fibrosis in the spinal peridural space are most common causes of post-laminectomy syndrome. Fibrin sealant agents membrane barriers commonly used for hemostasis sealing purposes surgery. Peridural may be a risk usage these topical agents. In this study, we aimed to compare effects Cova ™, Tisseel® Adcon ® Gel on development experimental rat model.Thirty-two Sprague Dawley female rats were randomly divided into 4 groups. Groups constituted as group 1; Cova™...

Spinal Cord Injury (SCI) is a devastating health problem both for the patient and clinician. Numerous treatment modalities have been studied to reverse effects of spinal cord injury. Herein reported comparison Alpha Lipoic Acid N-Acetyl Cysteine on rats with SCI.38 adult male Sprague-Dawley were randomly divided into 5 groups: only laminectomy, laminectomy trauma, trauma 100 mg/kg IP administration, 300 vehicle group (PEG). The model was Modified Allen Weight drop method. After procedure,...

The Fahr syndrome (FS) is a rare degenerative neurological disorder (its prevalence <0.5%). FS distinguished by the presence of abnormal bilateral intracranial calcifications with predilection for basal ganglia, also presented movement disorders such as parkinsonism, paresis, and speech disorders. Chronic subdural hematoma (CSH), which typically result mild head trauma, regularly encountered condition in elderly. A 63-year-old man has referred to our clinic from another hospital history...

Spinal osteochondromas are very rare, and they present with nonspecific localized pain owing to bone involvement. Diagnosis is made based on direct X-ray computed tomography (CT) imaging of the exophytic lesion pedunculated or sessile structure. Although asymptomatic patients can be observed, surgical excision main treatment modality. We case a 34-year-old man solitary thoracic osteochondroma. The patient presented complaints in legs, numbness, inability walk. diagnosis was confirmed CT...