A5026758616- Orthopedic Surgery and Rehabilitation
- Shoulder Injury and Treatment
- Elbow and Forearm Trauma Treatment
- Hip disorders and treatments
- Orthopaedic implants and arthroplasty
- Renal and related cancers
- Knee injuries and reconstruction techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Bone fractures and treatments
- Medical Malpractice and Liability Issues
- Musculoskeletal synovial abnormalities and treatments
- Renal cell carcinoma treatment
- Peripheral Nerve Disorders
- Musculoskeletal pain and rehabilitation
- Shoulder and Clavicle Injuries
- Diabetes Treatment and Management
- Lung Cancer Research Studies
- Total Knee Arthroplasty Outcomes
- Patient Satisfaction in Healthcare
- Neuroendocrine Tumor Research Advances
- Pituitary Gland Disorders and Treatments
- Vestibular and auditory disorders
- Pain Management and Treatment
- Economic and Financial Impacts of Cancer
- Smart Materials for Construction
University of Utah
2019-2024
University of Michigan
2024
Rogers (United States)
2010-2023
University of Bristol
2022-2023
University of Washington
2023
Orthopedic Center
2022
MRC Epidemiology Unit
2022
Orthopaedic Center
2019-2021
Associated Press
2019
Flinders University
2019
Therapies that target the vascular endothelial growth factor (VEGF) pathway cause hypertension, but mechanism remains unknown. This cross-sectional study tested hypothesis VEGF inhibition causes hypertension by suppressing VEGF-mediated vasodilatory pathways. Urine was collected from 80 patients with metastatic renal cell carcinoma 2002 to 2009, 40 at baseline and while on inhibitors. Measured urinary biomarkers include albumin, metabolites of nitric oxide (NO) its downstream effector cGMP,...
Intra-articular corticosteroid injections are often used for short-term pain relief in patients with knee osteoarthritis (OA). This study investigates the efficacy of intra-articular symptomatic OA and factors that affect treatment response.This prospective, multicentered cohort had 100 participants radiographic evidence enrolled. Participants received one injection into affected were evaluated before (baseline) at 3 weeks, 6 months, months after injection.Participants' Visual Numeric Scale...
To assess the effectiveness, safety, and treatment patterns of anti-angiogenic agents in metastatic renal cell carcinoma (mRCC) tertiary clinical practice settings.We retrospectively reviewed medical records two oncology centres USA for all patients treated while off trials from April 2003 to June 2008 who met entry criteria received one or more prescriptions sunitinib sorafenib, intravenous administrations bevacizumab (off-label) as first-line treatment. The objective response rate (ORR) by...
In the senior author's (X.L.) orthopaedic sports medicine clinic in United States (US), patients appear to have difficulty finding physical therapy (PT) practices that accept Medicaid insurance for postoperative rehabilitation.To determine access PT services privately insured versus those with who underwent anterior cruciate ligament (ACL) reconstruction largest metropolitan area state of Massachusetts, which expansion as part Affordable Care Act.Cross-sectional study.Locations offering were...
Rotator cuff repair (RCR) is an effective procedure to relieve shoulder pain and dysfunction. Postoperative physical therapy (PT) plays integral role in the overall success of RCR. Insurance status has been shown be important predictor postoperative PT utilization. This study evaluated effect insurance on access services following One hundred thirty-eight clinics were contacted Greater Boston metropolitan area. Clinics two separate occasions presented with a fictitious acutely RCR patient...
More than 150 accredited orthopaedic residency programs exist in the United States with more 3,300 residents. Every year, between 600 and 800 surgeons complete board certification. However, little is known about what residents use prefer of many resources available to them. The purpose this study understand how across country prioritize educational resources.An 18-question survey subqueries was compiled on REDCap (Research Electronic Data Capture) platform. Residents were reached through...
Abstract Background There is no gold standard patient-reported outcome measure (PROM) in hand surgery. As a result, diverse array of PROM instruments have been utilized across centers over time. Lack score interchangeability limits the ability to compare or conglomerate scores when new are introduced. Our aim was develop linkage for PROMIS UE CAT v1.2 and PF crosswalk tables interconversion between these PROMs. Methods Retrospective review conducted identify adult (≥ 18y) patients seen by...
Background: Abnormal proximal femoral morphology in femoroacetabular impingement syndrome (FAIS) identifiable on the anteroposterior (AP) pelvic radiograph has been described as “pistol grip” deformity. The effect of a superior cam deformity identified this radiographic view remains unknown. Purposes: To assess relationship between AP (AP alpha angle [AP AA] >55°) and cartilage injury; to labral determine if patient factors are correlated with injury. Study Design: Case-control study;...
Background: It is unclear which carpal tunnel release (CTR) strategy (i.e., combination of surgical technique and setting) most cost-effective. A cost-effectiveness analysis was performed to compare (1) open CTR in the procedure room (OCTR/PR), (2) OCTR operating (OCTR/OR), (3) endoscopic (ECTR/OR). Methods: decision analytic model used costs health utilities between treatment strategies. Utility probability parameters were identified from literature. Medical estimated with Medicare...
Preclinical and genetic studies suggest that impaired glucose-dependent insulinotropic polypeptide receptor (GIPR) signaling worsens glycemic control. The relationship between GIPR the risk of cancers influenced by glucose homeostasis is unclear. We examined association a variant in
Opioids are commonly used to treat postoperative pain; however, guidelines vary regarding safe opioid use after hip arthroscopy.The purposes were (1) identify risk factors for persistent use, (2) assess the effect of on outcomes, and (3) describe common prescribing patterns arthroscopy. It was hypothesized that preoperative would affect complication rates result in greater use.Case-control study; Level evidence 3.The Utah State All Payer Claims Database queried patients who underwent...
Scaphoid fractures are common injuries with high risk of nonunion. Various fixation techniques exist for managing scaphoid nonunions, including Kirschner wires, single or dual headless compression screws, combination techniques, volar plating, and compressive staple fixation. The indication each technique varies depending on the patient, type nonunion, clinical scenario.
Hip arthroscopic surgery has become an increasingly common surgical technique to diagnose and treat various hip abnormalities. While increased efficacy been reported, debate remains regarding appropriate indications. Multiple factors including patient demographics, procedure, underlying disease have associated with poor outcomes. Preoperative diagnostic treatment interventions physical therapy injections may affect indications outcomes.To identify characteristics preoperative risk of early...
Patient expectations before cubital tunnel release (CuTR), a common procedure that leads to incomplete symptom resolution for many patients, are unclear. Study purposes included (1) describing preoperative patient expectations, and (2) identifying factors affecting expectations.Included patients underwent isolated unilateral CuTR between 2015 2021 at single tertiary academic medical center. Expectations regarding the level of symptomatic improvement were queried preoperatively. Univariate...
The role of chemotherapy in squamous cell carcinoma the larynx has not been clearly defined. Whilst toxic regimes may confer a marginal improvement survival, surgery and radiotherapy remain mainstay treatment. Somatostatin is naturally occurring peptide, which exerts antiproliferative antiangiogenic effects via five membrane-bound receptor subtypes. expression somatostatin subtypes (SSTRs) 1 2 was studied benign, pre-malignant malignant laryngeal specimens. Epithelial SSTR1 detected 4/6...
Background: Patients with hip pathology, such as femoroacetabular impingement (FAI) or dysplasia, are known to sustain chondral delamination injuries identifiable during arthroscopy, an incidence of 44% 75%. There studies focused on understanding acetabular flap viability, but there is a dearth research regarding the viability femoral head cartilage overlying cam deformity in FAI. Purpose: To describe and immunohistochemistry staining patterns setting Study Design: Descriptive laboratory...
Acoustic neuroma is a benign tumour, which develops through an overproliferation of Schwann cells along the vestibular nerve. Somatostatin naturally occurring peptide, exerts antiproliferative and antiangiogenic effects via five membrane bound receptor subtypes. The aim this study was to determine whether somatostatin subtypes (SSTRs) 1, 2, 3, 5 are present in acoustic neuromas.The expression SSTRs studied both blood vessels eight specimens, by means immunohistochemistry using novel rabbit...