A5087402648- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Cancer Research and Treatments
- Extracellular vesicles in disease
- Nanoplatforms for cancer theranostics
- Radiation Therapy and Dosimetry
- Hormonal and reproductive studies
- Radiopharmaceutical Chemistry and Applications
- Renal and Vascular Pathologies
- Cancer, Lipids, and Metabolism
- PARP inhibition in cancer therapy
- Urologic and reproductive health conditions
- Pediatric Urology and Nephrology Studies
- Cancer-related gene regulation
- Cancer, Stress, Anesthesia, and Immune Response
- Cancer, Hypoxia, and Metabolism
- Cancer Cells and Metastasis
- Biomarkers in Disease Mechanisms
- Renal cell carcinoma treatment
- Mathematical Biology Tumor Growth
- Kidney Stones and Urolithiasis Treatments
RWTH Aachen University
2024
Saarland University
2013-2022
Abstract The unique microenvironment of the prostate plays a crucial role in development and progression cancer (PCa). We examined effects cancer-associated fibroblasts (CAFs) on PCa using patient-derived fibroblast primary cultures representative orthotopic xenograft model. Primary CAFs, non-cancer-associated (NCAFs) benign hyperplasia-associated (BPHFs) were generated from tissue specimens. These coinjected together with cells (LuCaP136 spheroids or LNCaP cells) xenografts to investigate...
Radical prostatectomy in oligometastatic prostate cancer is a matter of intense debate. Besides avoiding local complications, it hypothesized that primary tumor resection may result better oncological outcomes. The aim our study was to analyze the effect on disease progression an orthotopic mouse model. First, optimal time point for resection, when metastases have already occurred, but still resectable, determined as 8 weeks after inoculation 5 × 105 LuCaP136 cells. In second vivo...
Hydronephrosis is essential in the diagnosis of renal colic. We automated detection hydronephrosis from ultrasound images to standardize therapy and reduce misdiagnosis
To determine the outcomes of complete surgical resection T4 prostate cancer after inductive androgen-deprivation therapy (ADT), as ADT and subsequent radical prostatectomy (RP) is not recommended by any guideline yet.A monocentric RP database was queried for patients initially diagnosed with cancer, considered primarily inoperable because a fixed mass defined rectal examination in combination high PSA level and/or large foci biopsy confirmed undifferentiated cancer. Treatment consisted...
You have accessJournal of UrologyProstate Cancer: Advanced (including Drug Therapy) II1 Apr 2016MP50-04 NEOADJUVANT ANDROGEN DEPRIVATION IN PRIMARILY INOPERABLE PROSTATE CANCER: CONSECUTIVE ASSESSMENT OF PERI-AND POSTOPERATIVE OUTCOMES Turkan Hajili, Carsten Ohlmann, Johannes Linxweiler, Stefan Siemer, Michael Stoeckle, and Matthias Saar HajiliTurkan Hajili More articles by this author , OhlmannCarsten Ohlmann LinxweilerJohannes Linxweiler SiemerStefan Siemer StoeckleMichael Stoeckle...
You have accessJournal of UrologyProstate Cancer: Basic Research & Pathophysiology I (MP16)1 Apr 2020MP16-18 THE ROLE OF CANCER-ASSOCIATED FIBROBLASTS AND THEIR EXTRACELLULAR VESICLES IN PROSTATE CANCER PROGRESSION Johannes Linxweiler*, Angela Zaccagnino, Dirk Himbert, Turkan Hajili, Philip Zeuschner, Christina Körbel, Michael Stöckle, D. Menger, Matthias Saar, and Kerstin Junker Linxweiler*Johannes Linxweiler* More articles by this author , ZaccagninoAngela Zaccagnino HimbertDirk Himbert...
You have accessJournal of UrologyCME1 May 2022PD41-12 FROM BIOPSY TO DIAGNOSIS IN 30 MIN: REMOTE INSTANT PROSTATE PATHOLOGY BASED ON ARTIFICIAL INTELLIGENCE ENHANCED ULTRASOUND (AI-US) Hamza Aljabali, Jakob Heidborn, Turkan Hajili, Kristina Greimelmaier, Jeremias Wohlschläger, Stephan Kruck, Gerd Reis, and Tillmann Loch AljabaliHamza Aljabali More articles by this author , HeidbornJakob Heidborn HajiliTurkan Hajili GreimelmaierKristina Greimelmaier WohlschlägerJeremias Wohlschläger...