A5013924427- Immunodeficiency and Autoimmune Disorders
- Pediatric health and respiratory diseases
- Blood disorders and treatments
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Diabetes and associated disorders
- Blood groups and transfusion
- Asthma and respiratory diseases
- Respiratory viral infections research
- Inhalation and Respiratory Drug Delivery
- Medical and Biological Ozone Research
- T-cell and B-cell Immunology
- Pneumocystis jirovecii pneumonia detection and treatment
- Child and Adolescent Health
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Platelet Disorders and Treatments
- Celiac Disease Research and Management
- Vitamin D Research Studies
- Inflammatory Myopathies and Dermatomyositis
- Mycobacterium research and diagnosis
- SARS-CoV-2 and COVID-19 Research
- Skin Diseases and Diabetes
- Hepatitis B Virus Studies
- Cystic Fibrosis Research Advances
- Immune responses and vaccinations
- Immune Cell Function and Interaction
Wroclaw Medical University
2013-2024
University of Wrocław
2003-2019
Wojewódzki Szpital Specjalistyczny im. J. Gromkowskiego we Wrocławiu
2013-2018
I.Horbachevsky Ternopil National Medical University
2018
Dolnośląskie Centrum Onkologii
2018
Wojewódzki Szpital Specjalistyczny we Wrocławiu
2018
Niepubliczna Wyższa Szkoła Medyczna
2003-2011
Abstract Inherited biallelic mutations of the ATM gene are responsible for development ataxia telangiectasia ( AT ). The objective present study was to conduct molecular analysis in a cohort 24 Polish patients with ataxia‐telangiectasia aim being provide an updated mutational spectrum patients. As result analysis, status recurrent mutation confirmed and ten new variants were detected. Application MLPA allowed detection large genomic deletion. Previously, this type had never been seen our...
At the beginning of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic, patients with inborn errors immunity (IEI) appeared to be particularly vulnerable a severe course disease. It quickly turned out that only some IEI groups are associated high risk infection. However, data on Disease 2019 (COVID-19) in still insufficient, especially children; hence, further analyses required. The retrospective study included 155 unvaccinated people IEI: 105 children and 50 adults (67.7%...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Boyarchuk O, Lewandowicz-Uszyńska A, Kinash M, Haliyash N, Sahal I, Kovalchuk T. Physicians’ awareness concerning primary immunodeficiencies in the Ternopil Region of Ukraine. Pediatria Polska - Polish Journal Paediatrics. 2018;93(3):221-228. doi:10.5114/polp.2018.77435. APA Boyarchuk, O., Lewandowicz-Uszyńska, A., Kinash, M., Haliyash, N., Sahal, I., & Kovalchuk, (2018). Paediatrics, 93(3), 221-228....
Deficits in disorders of humoral immunity associated with a deficit antibodies are the most common primary immunodeficiency. Total IgG and subclasses measurements used to diagnose, differentiate control patients secondary immunodeficiencies.The purpose study was analyze structure group according difference between total sum determine factors affecting level this difference. This based on data collected from 670 children referred Department Clinical Immunology Pediatrics order diagnose immune...
The aim of our study was to evaluate redox status, enzymatic and non-enzymatic antioxidant barriers, oxidative damage proteins, lipids DNA, as well concentration coenzyme Q10 vitamins A E in patients with chronic granulomatous disease (CGD). performed on fifteen Caucasian individuals (median age 24 years seven months) diagnosed CGD. mutation the NCF1 gene confirmed ten patients, CYBB five patients. We demonstrated high levels total oxidant status (TOS) stress index (OSI), (↑8-isoprostanes...
Data regarding the course of SARS-CoV-2 infection in children with primary immunodeficiency (PID) is insufficient. The purpose study was to evaluate morbidity and clinical COVID-19 ability produce anti-SARS-CoV-2 IgG antibodies PID.In this retrospective study, medical records 99 patients aged 0-18 were evaluated. divided into three groups: PID group (68.69%), control (19.19%) ongoing or previous paediatric inflammatory multisystem syndrome (12.12%). such as morbidity, outcome, antibody...
Today, when animals have become family members, thus bringing a whole spectrum of positive effects on both the mental and physical health people, more we must bear in mind potential hazards arising from such relationship order to make possessing companion pleasant safe. One threat is undoubtedly dirofilariosis. Dirofilariosis parasitic zoonosis caused by invasion mosquito-borne nematodes genus Dirofilaria. Man an accidental host parasite. Although dirofilariosis considered be endemic disease...
Abstract Background Primary immunodeficiences (PIDs) are a group of chronic, serious disorders in which the immune response is insufficient. In consequence, it leads to an increased susceptibility infections. Up date, there about 350 different classified that group. There also patients suffering from recurrent respiratory tract infections (RRTI), however doesn’t present any abnormalities terms conducted immunological tests. Many factors, including medical, can have impact on physical...
Abstract Background The correlation between primary immunodeficiencies (PIDs) and autoimmunity shows ethnic geographical diversity. aim of our study was to accumulate more data in paediatric PID population. Methods 58 children aged 1–17 with (study group) 14 age-matched immunocompetent individuals (control were included the study. Serum levels 17 different specific IgG antibodies against autoantigens measured by means a quantitative enzyme immunoassay. Immunoglobulin analysed relation...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Lewandowicz-Uszyńska A, Zwonarz K, Chmielarska J. Review paperThe 22q11 microdeletion syndrome in children. Central European Journal of Immunology. 2013;38(2):271-275. doi:10.5114/ceji.2013.35220. APA Lewandowicz-Uszyńska, A., Zwonarz, K., & Chmielarska, (2013). Immunology, 38(2), 271-275. https://doi.org/10.5114/ceji.2013.35220 Chicago Aleksandra, Katarzyna and Joanna Chmielarska. 2013. "Review children"....
The human immune system’s response to infection is closely related with the type of pathogen. First, a rapid, metabolically inexpensive and non-specific innate immunity induced, then specific acquired activated. In bacterial infections caused by intracellular pathogens, main role played cellular response. extracellular crucial antibodies. clinical symptoms viral very often are similar, which why diagnosing them based only on medical history physical examination insufficient. To identify...
The effect of vitamin D levels on the response to hepatitis B vaccine in childhood and induced antibodies against surface antigen (anti-HBs) is not yet well understood. study aimed investigate relationship between age, serum 25-hydroxyvitamin (25(OH)D) concentration anti-HBs titer among children under 12 years old. Serum 25(OH)D were determined 352 healthy Caucasian with average age 4.2 (2.5; 6.3) years. All vaccinated 3 doses (Engerix-B, GlaxoSmithKline Pharmaceuticals Limited) infancy...