A5054069021- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Cardiac Structural Anomalies and Repair
- Cardiovascular Effects of Exercise
- Cardiac, Anesthesia and Surgical Outcomes
- Congenital Heart Disease Studies
- Blood Pressure and Hypertension Studies
- Heart Rate Variability and Autonomic Control
- Aortic Disease and Treatment Approaches
- Infective Endocarditis Diagnosis and Management
- Cardiac tumors and thrombi
- Coronary Artery Anomalies
- Cardiovascular Disease and Adiposity
- Cardiovascular Health and Disease Prevention
- Cardiovascular and exercise physiology
- Cardiac and Coronary Surgery Techniques
- COVID-19 Clinical Research Studies
- Cardiac Imaging and Diagnostics
- Gut microbiota and health
- Cardiac Health and Mental Health
- Cardiomyopathy and Myosin Studies
- Pulmonary Hypertension Research and Treatments
- Sarcoma Diagnosis and Treatment
- Renin-Angiotensin System Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
Instituto Nacional de Cardiología
2016-2025
Universidad Anáhuac
2025
Universidad Nacional Autónoma de México
2024
Instituto Nacional de Cardiologia
2010-2020
Background Systemic arterial hypertension is linked to a heightened risk of cardiovascular diseases on global scale. In Mexico, nearly half adults in vulnerable conditions experience hypertension. Imbalance the oral and intestinal microbiota composition has been observed patients with hypertension, documented by decrease bacteria producing short-chain fatty acids, which play critical role blood pressure regulation. Aim To examine cytokines’ profile assess characteristics gut obesity-related...
(1) Background: Although all severe calcific aortic stenosis (SCAS) patients have decreased sympathetic compensation to active standing, it has not been studied in who underwent valve replacement (AVR). The objective was assess the association of heart rate variability (HRV) response an orthostatic challenge before AVR with risk complications or death during postoperative period SCAS. (2) Methods: This observational study included 49 patients. cardiac autonomic activity assessed by HRV...
Introduction: Aortic valve disease (AVD) is an inflammatory, lipid infiltration and calcification that has been associated with changes in the conventional linear heart rate variability (HRV) indices showing a marked shift towards sympathetic predominance deterioration of autonomic control. Objective: To explore HRV dynamics AVD patients through nonlinear methods by recurrence quantification analysis (RQA). Methods: In total, 127 subjects participated cross-sectional study categorized into...
Latin American registries of clinical and demographic profiles ACHD are scarce. International guidelines classify disease complexity with different approaches. With these two regards, a registry was carried out to examine factors associated mortality compare severity classifications in our population.
A paucity of data exists about left atrium (LA) function in aortic valve stenosis (AS) or regurgitation (AR). Two-dimensional speckle tracking echocardiography allows the noninvasive study LA functional disturbances disease and their impact development pulmonary hypertension (PH).Consecutive patients with moderate severe AS AR were included. Left ventricle (LV) strain quantification was performed. We included 42 30 AR. Differences not found volumes The volumetric derangements parallel...
Ischaemic mitral regurgitation (IMR) is consequence of left ventricular (LV) remodelling after myocardial infarction. In some cases, the valve enlarges to compensate for LV and tenting, improving its coaptation; a process termed 'plasticity'. We sought identify clinical echocardiographic factors associated with plasticity in patients chronic inferior infarction (CII).This study included 91 revascularized CII 46 controls. Plasticity IMR severity were evaluated by 2D transthoracic...
Previous studies suggest a relationship of the epicardial adipose tissue (EAT) with progression and calcification atherosclerotic plaque; however, it is unknown if this expresses genes that may participate on these processes expression regulated by high-density lipoprotein (HDL) subclasses.To explore possibility, we determined mRNA qPCR pro-calcifying gene (osteopontin (OPN)), two anti-calcifying (osteoprotegerin (OPG) osteonectin (ON)), in biopsies EAT obtained from 15 patients coronary...
The I/D insertion/deletion polymorphism of the angiotensin-converting enzyme has been related to hypertension. This also seems have gender implications. Angiotensin II contributes production and release oxygen reactive species that react with nitric oxide, inactivating its effects.To establish whether ACE correlates oxide plasma metabolites in healthy men women.Among 896 subjects between 18 30 years age range, 138 fulfilled inclusion criteria. was identified by polymerase chain reaction,...
release of reactive oxygen species resulting in fibrosis, hypertrophy and myocardial apoptosis. 6)7)Patients with OW/O develop ventricular remodeling has been shown that histological features such as: myocyte hypertrophy, tissue degeneration inflammation, are proportional to the degree obesity. 8)Hypertrophy context is generated under a range stimuli including insulin
The pandemic SARS coronavirus 2 utilizes efficient mechanisms to establish infection and evade the immune system. Established leads severe inflammation in susceptible patients, main hallmark of progression disease (COVID-19). Knowledge has expanded rapidly. As emerges as central pathophysiological feature COVID-19, elucidating how system, lungs gut communicate interact with microbial components ecological niches that conform human microbiome will shed light on are promoted. Studying COVID-19...
In recent decades, adults living with congenital heart disease (ACHD) have improved their survival, thus increasing predisposition to the onset of cardiometabolic risk factors and chronic health conditions.
Aortic stenosis is a progressive heart valve disorder characterized by calcification of the leaflets. Heart rate variability (HRV) analysis has been proposed for assessing response to autonomic activity, which documented be altered in different cardiac diseases. The objective study was evaluate changes HRV patients with aortic an active standing challenge. Twenty-two volunteers without alterations (NAV) and twenty-five diagnosed moderate severe calcific (AVS) participated this...
Aortic-valve sclerosis increases cardiovascular mortality risk and precedes aortic-valve stenosis, but its mechanisms are not well understood. The purpose of this study was to compare the cardiac autonomic modulation inflammation markers between subjects with normal leaflets sclerosis. According 2-D transthoracic echocardiograms, 61 middle-aged volunteers without chronic or acute illnesses were classified in two groups: no (NAVS, N = 16) (AVS, 45). An electrocardiogram at supine position...
The EuroSCORE (European System for cardiac operative risk evaluation) stratifies surgery in easy and accessible manner; it was validated North America with good results but many countries of Latin is used routinely without prior validation. Our objective to validate the patients valve at Instituto Nacional de Cardiología Ignacio Chávez (INCICh) México.EuroSCORE additive logistic models were predict mortality adults undergoing from march 2004 2008. goodness fit test Hosmer-Lemeshow evaluate...
<p>Chagas disease constitutes a relatively prevalent condition in Latin America and is increasing worldwide. With wide spectrum of clinical subsets. Imaging modalities are critical for adequate diagnosis, staging prognosis this entity. Currently Echocardiography Cardiac Magnetic Resonance the most valuable techniques purpose. Evidence both has increased last years, as role advanced such Speckle Tracking been explored we aim to review evidence imaging patients with Chagas Heart...
Excessive weight and obesity (EwO) are independent factors in the development of heart failure; they lead to a state myocardiopathy via inflammatory hormonal mechanisms. If excessively accumulated, epicardial fat favors proinflammatory state. Ventricular asynchrony is marker failure progression has been poorly studied EwO. The objective was evaluate relation between fat, body mass index (BMI) mechanical synchrony measured by echocardiography, healthy individuals with EwO.We included 55 ages...
The aim of this work was to obtain insights the participation autonomic nervous system in different stages calcific aortic valve disease (CAVD) by heart rate variability (HRV) analysis. Studying subjects with no impairments and CAVD patients, we also sought quantify independent contribution or explanatory capacity echocardiographic parameters involved HRV changes caused active standing using hierarchical partitioning models consider other variables potential confounders. We detected smaller...
Objective: This article aims to assess the adherence level second-line therapy for cardiovascular prevention in a tertiary hospital Mexico City and identify key barriers adequate pharmacological adherence.Methods: A single-center prospective cross-sectional study was conducted between August 2018 February 2020.Sociodemographic data were collected, Morisky medication scale performed.Directed interviews during medical consultations also determine reasons non-adherence.Results: Showed that out...
Introduction: Central blood pressure (CBP) is considered a measure of prognostic value for cardiovascular risk.In turn, the aortic pulse wave velocity (PWVAo) and augmentation index (Aix) have been related to arterial stiffness risk.Controversies exist regarding reference values in different ethnic groups, ages, anthropometrics.The objective this study evaluate CBP parameters Mexican population by age, gender, anthropometry.Methods: Between 2015 2016, 1009 apparently healthy subjects were...
Several changes of the mitral valve (MV) morphology have been previously documented in ischaemic regurgitation (IMR) upon macro and microscopic examination. This study aimed to correlate echocardiographic MV thickening with IMR severity delineate histopathological basis from explanted leaflets.Two hundred fifty patients were included echo-group; these, 48 (19.2%) underwent surgical replacement (MVR), including them histology-group. By echocardiography, thickness anterior posterior leaflet...