A5085789068- Head and Neck Cancer Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Tracheal and airway disorders
- Thyroid Cancer Diagnosis and Treatment
- Cancer Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Airway Management and Intubation Techniques
- Head and Neck Anomalies
- Hip and Femur Fractures
- Cancer survivorship and care
- Family Support in Illness
- Innovations in Medical Education
- Frailty in Older Adults
- Nutrition and Health in Aging
- Cardiac, Anesthesia and Surgical Outcomes
- Dysphagia Assessment and Management
- Voice and Speech Disorders
- Lung Cancer Treatments and Mutations
- Pituitary Gland Disorders and Treatments
- Colorectal and Anal Carcinomas
- Patient-Provider Communication in Healthcare
- Nasal Surgery and Airway Studies
- Cystic Fibrosis Research Advances
- Peptidase Inhibition and Analysis
McGill University
2016-2025
McGill University Health Centre
2015-2025
Jewish General Hospital
2016-2025
Royal Victoria Hospital
2016-2025
Université de Montréal
2021-2024
University of Pittsburgh Medical Center
2021-2023
Royal Victoria Regional Health Centre
2019
Montreal Children's Hospital
2018
Head and neck cancer (HNC) treatments are known to significantly affect functionality appearance, leading an increased risk for body image disturbances. Yet, few longitudinal studies exist examine in these patients. Based on a conceptual model, the current study aimed determine, patients newly diagnosed with HNC: (1) prevalence, level, course of concerns; (2) correlates upon diagnosis (pre-treatment) (3) predictors immediate post-treatment (4) association between concerns levels anxiety,...
ABSTRACT Background Airway obstruction secondary to chyle leak is an exceptionally rare phenomenon. Here, we describe this complication in a patient with anaplastic thyroid carcinoma (ATC) undergoing consolidative surgery after BRAF‐targeted therapy. Methods A 55‐year‐old man presented rapidly enlarging neck mass. Work‐up was consistent metastatic unresectable BRAF V600E ‐mutant ATC. After remarkable response neoadjuvant dabrafenib and trametinib, he underwent curative‐intent right...
ABSTRACT Background Neck hematoma following thyroid surgery is a potentially life‐threatening complication. Methods This retrospective case–control study reviewed neck reoperations (2009–2024), using 3:1 matching. Univariable analysis identified and delayed onset (≥ 6 h) risk factors, with odds ratios (ORs) 95% confidence intervals (CIs). Results Among 5502 surgeries, the incidence was 0.55% ( n = 30). The mean age 54 female‐to‐male ratio 7:3. Key factors included pre‐induction blood...
Patients with head and neck squamous cell cancer (HNSCC) are at a greater risk of developing pulmonary metastases and/or second primary lung cancer. However, it remains uncertain whether screening in these patients, when the initial staging studies negative, confers any survival benefit. To evaluate long-term outcomes patients HNSCC undergoing chest radiography vs low-dose computed tomography for metastasis This randomized parallel trial was conducted large academic hospital Canada enrolling...
Patients 65 years or older are the most frequent users of operative resources and also vulnerable to postoperative adverse events (AEs). Frailty indices increasingly being used for preoperative risk stratification within head neck cancer surgery, but models lack a multifactorial basis cannot be directly applied clinical practice. A practical index is needed clinicians gauge factors preoperatively.To develop short-term major AEs patients undergoing surgery.Cohort analysis from multiple...
Abstract Background A paradigm shift has led to de‐escalation trials for the treatment of HPV‐positive oropharynx cancer (OPC). The objective this study was assess ability tumor volume reduction on imaging predict pathological response neoadjuvant chemotherapy in patients with OPC. Methods prospective observational 54 OPC enrolled a clinical trial followed by surgery performed. Patients underwent three cycles induction (cisplatin/docetaxel); prechemotherapy and postchemotherapy were...
Abstract Background Neoadjuvant chemotherapy followed by surgery (NAC + S), a paradigm based on systemic escalation coupled with surgery‐based de‐escalation, is under investigation for treatment of HPV‐associated oropharynx cancer (OPC). Methods Prospective cohort patients non‐metastatic, p16 positive OPC enrolled in clinical trial NAC S was compared to historic undergoing concurrent chemoradiation (CCRT) compare disease‐free survival (DFS). Results Fifty‐five were treated and 142 CCRT....
The COVID-19 pandemic placed considerable strain on the healthcare system, leading to re-allocation of resources and implementation new practice guidelines. objective this study is assess impact guideline modifications head neck cancer (HNC) care at two tertiary centers in Canada.A retrospective cohort was conducted. HNC patients seen before after onset (pre-pandemic: July 1st, 2019, February 29th, 2020; pandemic: March 2020, October 31st, 2020) were included. pre-pandemic cohorts compared...
A longitudinal curriculum was developed in conjunction with anesthesiologists, otolaryngologists, emergency physicians and experts medical simulation education.Residents participated four different simulation-based training modules using animal models, cadavers, task trainers, crisis scenarios high fidelity manikins. Scenarios were based on various clinical settings (i.e. room, operating room) followed by video-assisted structured debriefings. Participants completed both a self-assessment...
Abstract Objectives Human papillomavirus (HPV) has prompted a need to further investigate how this new biomarker changes the head and neck cancer (HNC) psychosocial landscape. This study aimed to: (a) characterize sociodemographic, psychological, social profiles of patients with HPV‐positive versus ‐negative squamous cell carcinoma neck; (b) identify HPV status contributes anxiety depression (primary outcome), quality life (QoL), sexuality needs. Methods We conducted prospective longitudinal...
We ascertain the role of a low cervical paraspinal skeletal muscle index (CPSMI) as biomarker for poor treatment tolerance in patients with operable mucosal head and neck squamous cell carcinoma (HNSCC).
(1) Background: Patients and survivors of head neck cancer (HNC) are at a high risk developing body image concerns. Despite the prevalence concerns in patients with HNC, there is lack longitudinal research exploring wide array its associated determinants. The current study examined determinants course dissatisfaction HNC. (2) Methods: participated Structured Clinical Interviews self-administered questionnaires four time-points: (T1) upon diagnosis, (T2) 3 months post-diagnosis, (T3) 6 (T4)...
Importance Efforts are underway to deintensified treatment protocols for patients with human papillomavirus virus−associated oropharyngeal squamous cell carcinoma (HPV-OPSCC) achieve similar excellent oncologic outcomes while reducing treatment-related adverse effects. Transoral robotic surgery (TORS) as primary often requires adjuvant therapy due the high incidence of nodal metastasis. Treatment neoadjuvant chemotherapy followed by TORS and neck dissection (NECTORS), reserving radiation...
Ultrasound guided fine-needle aspiration (USFNA) biopsy of thyroid nodules often gives a result indeterminate pathology, placing specialists in difficult management situations. The aim this study is to evaluate the incidence malignancy patients undergoing surgery and correlate these results with McGill Thyroid Nodule Score (MTNS). We performed retrospective comparing USFNA results, MTNS histopathology between 2010 2012. Pre-operative were divided into three subgroups: benign, suspicious...
Objectives/Hypothesis Despite the transition to competency-based education in surgery, few standardized assessment tools exist otolaryngology training. In particular, myringotomy and tympanostomy tube insertion (M+T) is a common surgical procedure with validated available. Our objectives were develop an objective structured of operative skills M+T provide validity evidence for developed tool within Study Design Prospective study involving evaluation tool. Methods Through consultation panel...
Objective To identify clinicopathologic factors associated with a reduced intercarotid distance (ICD) and subgroups at risk for internal carotid artery injury during transsphenoidal surgery. Design A retrospective case-control study. Setting This study was conducted the McGill University Health Centre, university-affiliated tertiary care center. Participants Patients sellar or parasellar tumor nontumor controls were included in Main Outcome Measures The smallest between arteries clival,...
Background A commonly employed treatment for advanced staged oropharyngeal squamous cell carcinoma (OPSCC) is concurrent radiation and chemotherapy with cisplatin as the gold standard. Carboplatin reported to have same radiopotentiation properties a superior side effect profile; however, its use in head neck cancer has been limited due paucity of data hematologic effects. In this study, we describe our institution's experience carboplatin, paclitaxel over 10 year period. Methods...