A5038199525- Thyroid Cancer Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Head and Neck Anomalies
- BRCA gene mutations in cancer
- Parathyroid Disorders and Treatments
- Thyroid Disorders and Treatments
- Voice and Speech Disorders
- Salivary Gland Tumors Diagnosis and Treatment
- Protist diversity and phylogeny
- Radiomics and Machine Learning in Medical Imaging
- Pituitary Gland Disorders and Treatments
- Tracheal and airway disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Radiation Dose and Imaging
- Pain Management and Opioid Use
- Veterinary Equine Medical Research
- Patient-Provider Communication in Healthcare
- Neuroendocrine Tumor Research Advances
- Obstructive Sleep Apnea Research
- Head and Neck Cancer Studies
- S100 Proteins and Annexins
- Veterinary Orthopedics and Neurology
- Vitamin D Research Studies
- Anorectal Disease Treatments and Outcomes
- Genital Health and Disease
Jewish General Hospital
2016-2025
McGill University
2016-2025
Royal Victoria Hospital
2013-2025
McGill University Health Centre
2013-2025
Great Western Hospital
2010-2024
University of York
2019-2024
Rossdales Veterinary Surgeons
2007-2023
Los Alamos National Laboratory
2022
Penza State University
2019
Radiological Society of North America
2016
To determine whether mucosal sensory dysfunction is present at multiple upper-airway sites in patients with obstructive sleep apnea (OSA). Physiologic testing of consecutive OSA and nonsnoring controls. University hospital center. Thirty-nine subjects 17 Endoscopic was used to detection thresholds for air-pressure pulses delivered the oropharynx, velopharynx, hypopharynx, larynx (aryepiglottic eminence). The air-pulse stimulus intensity required elicit protective laryngeal adductor reflex...
Most of the literature on surgical site infections following treatment fractures ankle is based small series patients, focusing diabetics or elderly. None have described post-operative functional scores in those patients who develop an infection. We performed age- and gender-matched case-control study to identify patient- surgery-related risk factors for infection open reduction internal fixation a fracture ankle. Logistic regression analysis was used significant calculate odds ratios (OR)....
No study systematically has investigated the supportive care needs of general head and neck cancer patients using validated measures. These include physical daily living needs, health system information patient support psychological sexuality needs. Identifying unmet is a necessary first step to improving we provide seen in our oncology clinics. It recommended as intervention development Pan-Canadian Clinical Practice Guideline Canadian Partnership Against Cancer (see Howell, 2009). This...
Background: Although the current gold standard for diagnosing thyroid nodule malignancy is ultrasound-guided fine-needle aspiration (FNA) cytology, about 20-25% of cytological evaluations are considered indeterminate malignancy. This limitation has led to emergence next-generation sequencing panels, example, ThyroSeq v3 (TSv3), which recognize highly diagnostic genetic mutations common carcinomas in FNA samples and classify them as test-negative or test-positive, helping optimize treatment...
Background. The purpose of this study was to determine whether patients who undergo total thyroidectomy will have postoperative hypocalcemia develop when they reach the critical 6-hour serum levels defined as parathyroid hormone (PTH) ≥28 ng/L and simultaneous corrected calcium ≥2.14 mmol/L. Methods. This a prospective involving 70 consecutive patients. There were 51 women 19 men involved in study. mean age 49.3 years (range, 21–76 years). Patients had completion or neck dissections...
Inflammation may contribute to upper airway pathophysiology in obstructive sleep apnoea (OSA). Our objective was compare pro-inflammatory cytokine expression, oxidative stress and connective tissue deposition severe (n = 25) versus mild 17) OSA patients. Upper surgical specimens were separated by predominance of either mucosal or muscle tissue. Expression levels interleukin (IL)-1α, IL-6, interferon-γ, RANTES (regulated on activation, normal T-cell expressed secreted), transforming growth...
Ceramic Fuel Cells Limited (CFCL) has developed Gennex and BlueGen products that are highly efficient SOFC for the micro-CHP electrical generator markets operating on natural gas producing electricity to grid at 1 - 2 kWe. An efficiency (LHV) of 60% is being achieved by system net AC exported grid. additional 25% power available as heat. This paper describes how this in CFCL's product.
Objectives Transient post‐thyroidectomy hypocalcemia is a common complication following thyroid surgery. Studies have identified risk factors and possible ways to help predict with the intent of ultimately limiting its incidence. This study evaluates role patient gender as potential factor. Study Design A retrospective case series chart review 270 consecutive total thyroidectomy patients was conducted. Setting Jewish General Hospital, McGill University–affiliated hospital in Montreal,...
Molecular testing of thyroid nodules is a diagnostic tool used to better understand the nature nodules. The aim this study comprehend relationship between specific mutations and aggressive behavior tumour as demonstrated on postoperative pathological analysis.A retrospective chart review 103 cases was performed. Included were patients who had undergone molecular using panel that tests for 9 (ThyGenX®) found have malignant tumours. following gene alterations pre-operatively in nodules: BRAF...
Recent studies show that soil eukaryotic diversity is immense and dominated by micro-organisms. However, it unclear to what extent the processes shape distribution of in plants animals also apply Major diversification events multicellular organisms have often been attributed long-term climatic geological processes, but impact such on protist has received much less attention as their believed be largely cosmopolitan. Here, we quantified phylogeographical patterns Hyalosphenia papilio, a large...
ABSTRACT Modern cosmological surveys are delivering data sets characterized by unprecedented quality and statistical completeness; this trend is expected to continue in the future as new ground- space-based come online. In order maximally extract information from these observations, matching theoretical predictions needed. At low redshifts, probe non-linear regime of structure formation where simulations primary means obtaining required information. The computational cost sufficiently...
While some studies suggest that PTEN mutations correlate with a low-risk phenotype in pediatric thyroid nodules, the relationship between mutation and malignancy adult populations is abstruse. This study investigated whether result malignancy, these malignancies are aggressive. multicenter involved 316 patients who underwent preoperative molecular testing, subsequent lobectomy or total thyroidectomy at two quaternary care hospitals. A four-year retrospective review was performed on 16 charts...
ABSTRACT Background Neck hematoma following thyroid surgery is a potentially life‐threatening complication. Methods This retrospective case–control study reviewed neck reoperations (2009–2024), using 3:1 matching. Univariable analysis identified and delayed onset (≥ 6 h) risk factors, with odds ratios (ORs) 95% confidence intervals (CIs). Results Among 5502 surgeries, the incidence was 0.55% ( n = 30). The mean age 54 female‐to‐male ratio 7:3. Key factors included pre‐induction blood...
ABSTRACT Objective The prevalence of thyroid cancer has increased significantly. Aggressive subtypes papillary (AG‐PTC) and high‐grade follicular cell‐derived malignancies (HGFM) are that lie between well‐differentiated undifferentiated cancers, their management needs to be clarified. aim our study is describe the clinicopathological characteristics AG‐PTC HGFM assess prognostic value. Methods This was a retrospective chart review at single center patients with or HGFM. comprised poorly...
To determine the prevalence of obstructive sleep apnea (OSA) in patients with cancer oral cavity and oropharynx scheduled for primary surgical resection. correlate presence OSA occurrence postoperative morbidities this patient population.This was a prospective study involving 17 malignancies Consecutive were approached to undergo overnight polysomnography apnea-hypopnea index (AHI). defined by an AHI value > or = 20 events per hour. Postoperative evaluated blinded fashion completing...
To examine the prognostic difference in well-differentiated thyroid cancer between macroscopic extrathyroidal extension (ETE), which is appreciated operating room, vs microscopic ETE, only under microscope by pathologist.Retrospective medical record review.Tertiary care academic hospital.Among 582 patients, those who were surgically treated for stage III with a minimum 5-year follow-up included. Fifty-five patients (10%) (17 males and 38 females [mean age, 53.1 years]) met selection...
Parathyroid dysfunction leading to symptomatic hypocalcemia is not uncommon following a total or completion thyroidectomy and often associated with significant patient morbidity prolonged hospital stay. A simple, reliable indicator identify patients at risk would permit earlier pharmacologic prophylaxis avoid these adverse outcomes. We examined the role of intact parathormone (PTH) levels 1 hour after surgery as predictor post-thyroidectomy hypocalcemia.We prospectively reviewed cases...
Objective To study the rate of postoperative hypocalcemia following completion thyroidectomy (CT), in comparison with total (TT). Study Design and Setting A retrospective study, performed at McGill University Thyroid Cancer Center, Montreal, Quebec, Canada, from 2007 to 2012. Subjects Methods Medical records adult patients undergoing CT TT operated by a single surgeon were reviewed. Data extracted for demographics, calcium levels, surgical logs, final pathology. Hypocalcemia was defined as...