A5003735811- Nanoparticles: synthesis and applications
- Advanced Nanomaterials in Catalysis
- Quantum Dots Synthesis And Properties
- Invertebrate Immune Response Mechanisms
- Epigenetics and DNA Methylation
- Chalcogenide Semiconductor Thin Films
- Pluripotent Stem Cells Research
- Antifungal resistance and susceptibility
- Neurobiology and Insect Physiology Research
- Genomics and Chromatin Dynamics
- Fungal Infections and Studies
- Plant Molecular Biology Research
- Biochemical effects in animals
- Luminescence Properties of Advanced Materials
- CRISPR and Genetic Engineering
- Graphene and Nanomaterials Applications
- Indoor Air Quality and Microbial Exposure
- Nanocluster Synthesis and Applications
- Layered Double Hydroxides Synthesis and Applications
- Heat shock proteins research
- Hippo pathway signaling and YAP/TAZ
- Retinal and Macular Surgery
- Developmental Biology and Gene Regulation
- Insect and Pesticide Research
- Connexins and lens biology
Universidade de São Paulo
2008-2024
Universidade Federal de Alagoas
2021-2024
University of Michigan
2017-2023
Article13 October 2017Open Access Source DataTransparent process RBPJ/CBF1 interacts with L3MBTL3/MBT1 to promote repression of Notch signaling via histone demethylase KDM1A/LSD1 Tao Xu Department Pathology, University Michigan Medical School, Ann Arbor, MI, USA Search for more papers by this author Sung-Soo Park Benedetto Daniele Giaimo Institute Biochemistry, Giessen, Germany Daniel Hall Molecular Genetics, Biochemistry and Microbiology, Cincinnati College Medicine, Cincinnati, OH,...
Insect hexamerins have long been known as storage proteins that are massively synthesized by the larval fat body and secreted into hemolymph. Following larval-to-pupal molt, sequestered via receptor-mediated endocytosis, broken up, used amino acid resources for metamorphosis. In honey bee, transcript protein subunit of a hexamerin, HEX 70a, were also detected in ovaries testes. Aiming to identify subcellular localization 70a female male gonads, we specific antibody whole mount preparations...
Titanium dioxide (TiO2) nanoparticles (NPs) are widely used in industry and commercial products. Thus, their potential risks to the environment human health must be evaluated. Doping NPs with certain ions makes it possible mix properties or generate new ones. order track TiO2 biological assays, doping europium (Eu3+) was performed, which luminesce red. Here, we synthesized Eu3+-doped nanocrystals (NCs) anatase phase verify toxicity at different concentrations Drosophila melanogaster...
Larval tissues undergo programmed cell death (PCD) during Drosophila metamorphosis. PCD is triggered in a stage and tissue-specific fashion response to ecdysone pulses. The understanding of how induces the tissue-specificity remains obscure. Several steroid-regulated primary genes have been shown act as key regulators cellular responses by inducing cascade transcriptional regulation late responsive genes. In this article, authors identify Fhos gene that required for larval salivary gland...
Hypertension is considered one of the most critical risk factors for COVID-19. Evidence suggests that SARS-CoV-2 infection produces intense effects on cardiovascular system by weakening wall large vessels via vasa-vasorum. In this commentary, we propose invades carotid and aortic baroreceptors, leading to nucleus tractus solitari (NTS) paraventricular hypothalamic (PVN), such dysregulation NTS PVN following causes blood pressure alteration at central level. We additionally explored...
EMC1 is part of the endoplasmic reticulum (ER) membrane protein complex, whose functions include insertion transmembrane proteins into ER membrane, ER-mitochondria contact, and lipid exchange. Here, we show that
Background: Fungi are ubiquitous microorganisms that easily dispersed through the air. In healthcare environments, indoor air can favor spread of healthcare-associated fungal infections, compromising mainly immunocompromised hospitalized individuals. Thus, this study aimed to evaluate contamination in investigating presence potentially pathogenic yeasts. Methods: Indoor samples were collected from twelve environments (hospital and medical clinics). After growth, isolation, purification yeast...
The Drosophila roughest (rst) locus encodes an immunoglobulin superfamily transmembrane glycoprotein implicated in a variety of embryonic and postembryonic developmental processes. Here we demonstrate previously unnoticed role for this gene the autophagic elimination larval salivary glands during early pupal stages by showing that overexpression Rst protein ectodomain pupa leads to persistence up at least 12 hours after head eversion, although with variable penetrance. same phenotype is...
Coordinated regulation of gene activity by transcriptional and translational mechanisms poise stem cells for a timely cell-state transition during differentiation. Although important all stemness-to-differentiation transitions, mechanistic understanding the fine-tuning transcription is lacking due to compensatory effect control. We used intermediate neural progenitor (INP) identity commitment define that fine-tune stemness in fly (neuroblasts). demonstrate factor FruitlessC (FruC) binds...
Introduction-Aims: Fungi are ubiquitous microorganisms that easily dispersed through the air. In healthcare environments, indoor air can favor spread of healthcare-associated fungal infections, compromising mainly immunocompromised hospitalized individuals. Therefore, this study aimed to evaluate contamination in investigating presence potentially pathogenic yeasts. Method: Indoor samples were collected from 12 environments (hospital and medical clinics). After growth, isolation,...
Drosophila melanogaster is undoubtedly one of the most useful model organisms in biology. Initially used solidifying principles heredity, and establishing basic concepts population genetics synthetic theory evolution, it can currently offer scientists much more: possibility investigating a plethora cellular biological mechanisms, from development function immune system to animal neurogenesis, tumorigenesis beyond. Extensive resources are available for community researchers worldwide,...
Doping nanoparticles represents a strategy for modulating the energy levels and surface states of nanocrystals (NCs), thereby enhancing their efficiency mitigating toxicity. Thus, we herein focus on successful synthesis pure gold (Au)-doped zinc oxide (ZnO) investigating physical-chemical properties evaluating applicability toxicity through
We explored the TiO2 nanocrystals (NCs) by introducing red luminescence via europium (Eu) ion doping (TiO2:Eu). Our objective was to optimize their biocompatibility and through calcium (Ca) co-doping. To...
In Brief Purpose: To investigate potential retinal neuroprotective effects of oral lamotrigine in rabbits after pars plana vitrectomy (PPV) and intravitreal silicone oil injection (SOI). Methods: Twelve New Zealand (weight, 2.0–2.5 kg) underwent PPV with SOI on the right eye. For 30 days postoperatively, 6 received a daily dose (25 mg/kg), water. The animals were killed surgery. All retinas processed histologically, immunostained using glial fibrillary acidic protein (GFAP), analyzed by...
Abstract Coordinated regulation of stemness gene activity by transcriptional and translational mechanisms poise stem cells for a timely cell-state transition during differentiation. Although important all stemness-to-differentiation transitions, mechanistic understanding the fine-tuning transcription is lacking due to compensatory effect control. We used intermediate neural progenitor (INP) identity commitment define that fine-tune in fly (neuroblasts). demonstrate factor Fruitless C (Fru )...