A5011778942- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Transplantation: Methods and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac pacing and defibrillation studies
- Innovations in Medical Education
- Infective Endocarditis Diagnosis and Management
- Cardiac Arrest and Resuscitation
- Cardiac Imaging and Diagnostics
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Aortic Disease and Treatment Approaches
- Cardiovascular Function and Risk Factors
- Cardiac and Coronary Surgery Techniques
- Cardiac Ischemia and Reperfusion
- Organ Transplantation Techniques and Outcomes
- Health and Medical Research Impacts
- Fuel Cells and Related Materials
- Clinical Reasoning and Diagnostic Skills
- Advanced Battery Technologies Research
- Congenital Heart Disease Studies
- Aortic aneurysm repair treatments
- Cardiac tumors and thrombi
- Acute Myocardial Infarction Research
University of Ottawa
2014-2025
Fondazione Audiologica Varese
2022
Canadian Thoracic Society
2022
University of Colorado Anschutz Medical Campus
2021
Royal College of Physicians and Surgeons of Canada
2021
Laboratoire de Biologie du Développement
2018
University of Washington
2016
St. Michael's Hospital
2016
University Health Network
2016
University of Toronto
2016
Several centers favor replacing a diseased native heart valve with tissue rather than mechanical prosthesis, even in younger adult patients. However, long-term data supporting this approach are lacking. We examined the survival implications of selecting versus prosthesis at initial left-heart replacement cohort adults <60 years age who were followed for over 20 years.Comorbid and procedural available from 6554 patients underwent our institution last 35 years. Of these, 1512 contributed...
Increased circulating levels of the cardiac polypeptide hormones atrial natriuretic factor (ANF) and brain peptide (BNP) may be observed after orthotopic transplantation. Both hypertrophic inflammatory processes in allograft contribute to this increase, but no mechanistic explanation has been suggested for observation.Plasma immunoreactive ANF BNP determinations were performed 10 consecutive transplant patients. These correlated with degree rejection as reflected by histopathological...
Background— Evidence supporting the use of bioprostheses for heart valve replacement in young adults is accumulating. However, reoperation data, which may help guide clinical decision making patients, remains poorly defined literature. Methods and Results— We examined need 3975 patients who underwent first-time bioprosthetic aortic (AVR) (n=3152) or mitral (MVR) (n=823). There were 895 below age 60 years at bioprosthesis implant (AVR, n=636; MVR, n=259). The median interval to contemporary,...
Whether viability imaging can impact long-term patient outcomes is uncertain. The PARR-2 study (Positron Emission Tomography and Recovery Following Revascularization) showed a nonsignificant trend toward improved at 1 year using an F-18-fluorodeoxyglucose positron emission tomography (PET)-assisted strategy in patients with suspected ischemic cardiomyopathy. When adhered to PET recommendations, outcome benefit was observed. Long-term of imaging-assisted management have not previously been...
Enteral alimentation via small soft feeding tubes is becoming more common as the importance of nutrition recognized in debilitated patient. The monofilament wire stylets that stiffen these during their insertion may cause potentially lethal bronchopleural complications unless correct techniques are used and tube's position carefully checked before starting enteral nutrition.
To compare the long-term outcomes in women and men after valve replacement surgery.Observational study.Postoperative aortic (AVR) or mitral (MVR).3118 patients (1261 women, 1857 men) who underwent AVR MVR between 1976 2006 (2255 AVR, 863 MVR), with mean follow-up of 5.6 (4.5) years.The independent effect gender on risk complications (reoperation, stroke death) surgery using multivariate actuarial methods.After implantation an bioprosthesis, had a significantly lower rate reoperation compared...
The Medtronic Hancock II and the Carpentier-Edwards Perimount are among world's most commonly used aortic bioprostheses. However, a direct comparison of their clinical performance is lacking. To minimize biases inherent to between-center comparisons, we examined these prostheses within large, contemporary, single-center cohort.Between 1990 2007, 1659 patients (mean age, 73.1±9.3 years) underwent valve replacement with either (N=1021) or (N=638). Patients were prospectively followed-up serial...
Background— Postoperative cognitive deficits (POCDs) are a source of morbidity and occur frequently even in low-risk patients undergoing cardiac surgery. Predictors neurocognitive can identify potentially modifiable risk factors as well high-risk whom alternate revascularization strategies may be considered. Methods Results— 448 coronary surgery (coronary artery bypass graft [CABG]) underwent standardized preoperative postoperative testing part 2 randomized trials evaluating the effects mild...