A5089167747- Glioma Diagnosis and Treatment
- Ferroptosis and cancer prognosis
- Immune cells in cancer
- SARS-CoV-2 and COVID-19 Research
- Vibrio bacteria research studies
- CRISPR and Genetic Engineering
- Bacteriophages and microbial interactions
- Cancer Research and Treatments
- Epigenetics and DNA Methylation
- COVID-19 Clinical Research Studies
- vaccines and immunoinformatics approaches
- Genomics and Phylogenetic Studies
- Monoclonal and Polyclonal Antibodies Research
- Cancer Genomics and Diagnostics
- RNA modifications and cancer
- interferon and immune responses
- Cancer-related molecular mechanisms research
- Immune Cell Function and Interaction
- Nutrition, Genetics, and Disease
- Computational Drug Discovery Methods
- Advanced biosensing and bioanalysis techniques
- T-cell and B-cell Immunology
- HIV Research and Treatment
- Hemoglobinopathies and Related Disorders
- Child Nutrition and Water Access
Raiganj University
2024
Government Medical College
2024
American International University-Bangladesh
2024
University of Freiburg
2023-2024
University of Dhaka
2013-2023
Renewable Energy Systems (United States)
2023
Advantech AMT (Canada)
2023
Alpha and Omega Semiconductor (Bermuda)
2023
Robert Bosch (India)
2023
Custom Electronics (United States)
2023
Cancer is clearly the most deadly disease in developed world as one three people develop cancer during their lifetime.The cure for like Holy Grail since of existing treatments are not effective enough to provide full protection from this disease.In recent years burgeoning sophisticated genomic, proteomic and bioinformatics techniques has made it possible us get a glimpse intricate interplay numerous cellular genes regulatory genetic elements that responsible manifestation cancerous...
Abstract Quantum biological tunnelling for electron transfer is involved in controlling essential functions life such as cellular respiration and homoeostasis. Understanding the quantum effects biology has potential to modulate functions. Here we merge wireless nano-electrochemical tools with cancer cells control over trigger cell death. Gold bipolar nanoelectrodes functionalized redox-active cytochrome c a redox mediator zinc porphyrin are developed electric-field-stimulating bio-actuators,...
Spatiotemporal heterogeneity originating from genomic and transcriptional variation was found to contribute subtype switching in isocitrate dehydrogenase-1 wild-type glioblastoma (GBM) prior upon recurrence. Fluorescence-guided neurosurgical resection utilizing 5-aminolevulinic acid (5ALA) enables intraoperative visualization of infiltrative tumors outside the magnetic resonance imaging contrast-enhanced regions. The cell population functional status tumor responsible for enhancing...
Abstract Signaling through the AKT and ERK pathways controls cell proliferation. However, integrated regulation of this multistep process, involving signal processing, growth cycle progression, is poorly understood. Here, we study different hematopoietic types, in which signaling triggered by erythropoietin (Epo). Although these types share molecular network topology for pro‐proliferative Epo signaling, they exhibit distinct proliferative responses. Iterating quantitative experiments...
Acetylcholine-esterase (AchE) inhibitors are one of the most potent drug molecules against Alzheimer's disease (AD).But, patients treated with current AchE often experience severe side effects.Quercetin is a plant flavonoid compound which can act as inhibitor and it may be better alternative to in terms effectiveness no or fewer effects.Aims: The aim study was compare quercetin conventional search for candidate.Methods materials: Physico-chemical properties drugs were predicted using...
A major problem in designing vaccine for the dengue virus has been high antigenic variability envelope protein of different strains. In this study, a computational approach was adopted to identify multi-epitope candidate against that may be suitable large populations dengue-endemic regions. Different bioinformatics tools were exploited helped identification conserved immunological hot-spot protein. The also rendered prediction immunogenicity and population coverage proposed 'in silico'...
There are many wrong practices and perceptions of Infant Young Child Feeding (IYCF) prevalent among different socio-demographic groups.To observe IYCF mothers in a rural area West Bengal.Clinic-based cross-sectional descriptive study by interviewing 0-23 month old children. Appropriate response to each selected key question was assigned score + 1 for objective assessment. Data analysis done standard statistical methods using the software SPSS 13.0 (Kolkata, India) windows version....
Proteome-centric studies, although have identified numerous lncRNA-encoded polypeptides, lack differential expression analysis of lncRNA-peptidome across primary tissues, cell lines and cancer states. We established a computational-proteogenomic workflow involving re-processing publicly available LC-MS/MS data, which facilitated the identification tissue-specific universally expressed (UExp) lncRNA-polypeptides 14 human tissues 11 lines. The utility as cancer-biomarkers was investigated by...
ObjectivesUnderlying medical conditions are critical risk factors for COVID-19 susceptibility and its rapid clinical manifestation. Therefore, the preexisting burden of non-communicable diseases (NCDs) makes preparedness more challenging low- middle-income countries (LMICs). These have relied on vaccination campaigns as an effective measure to tackle COVID-19. In this study, we investigated impact comorbidities humoral antibody responses against specific receptor-binding domain (RBD)...
Bacteria have developed several defense mechanisms against bacteriophages over evolutionary time, but the concept of prokaryotic RNA interference mediated mechanism phages and other invading genetic elements has emerged only recently.
BackgroundThe dengue-infected patients with or without hemorrhagic manifestations, typically exhibit moderate to severe thrombocytopenia. A thrombopoietin receptor agonist – eltrombopag has been efficacious in correcting thrombocytopenia various pathological conditions including immune thrombocytopenia, chronic liver disease, and aplastic anemia. This study investigated the efficacy safety of correct dengue-mediated thrombocytopenia.MethodsIn this open-label, randomized controlled phase-II...
We aimed to measure the seroprevalences and levels of anti-SARS-CoV-2 IgG in children, unvaccinated vaccinated adults five districts Bangladesh thus, investigate association seroprevalence level with respect different attributes study participants.In present study, plasma were measured children (n = 202), 112), 439) using quantitative ELISA.The overall three groups participants 58.3% (90%CrI: 52.3-64.2%), 62.2% 54.4-70.0%) 90.7% 88.3-92.9%), respectively. Multivariate logistic linear...
Membrane‐bound angiotensin‐converting enzyme 2 ( ACE2 ) receptor acts as the entry point for novel coronavirus, SARS‐CoV‐2. Polymorphisms in gene may alter viral binding, regulate expression of ACE2, and thus, affect disease severity. In this study, 68 COVID‐19 patients with varying degrees severity 40 healthy controls were enrolled. The genetic landscape was explored by whole exome sequencing 29 individuals, specific regions analyzed rest participants via PCR, followed barcode‐tagged...
Diarrhea due to infection of enterotoxigenic Escherichia coli (ETEC) is great concern in several low and middle-income countries. ETEC considered be the most common cause diarrhea Bangladesh mainly spread through contaminated water food. pathogenesis mediated by expression enterotoxins colonization factors (CFs) that target intestinal mucosa. can survive for extended time periods water, where they are likely attacked bacteriophages. Antibiotic resistance amongst enteric pathogens therefore...
Background: Hepatocellular carcinoma (HCC) is one of the fatal cancer types worldwide, and a variety genetic factors are considered to be associated with this incidence. MDM2 gene plays pivotal role in various pathways, which essential combat tumor formation. The study aimed find out associations (T309G, rs2279744) polymorphism development HCC Bangladeshi population. Methods: A case-control on 100 patients 110 control subjects was conducted. genotyping (T309G) done using PCR-RFLP methods....