- Pulmonary Hypertension Research and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Respiratory Support and Mechanisms
- Transplantation: Methods and Outcomes
- Cardiovascular Function and Risk Factors
- Intensive Care Unit Cognitive Disorders
- Long-Term Effects of COVID-19
- Genetics and Neurodevelopmental Disorders
- Pleural and Pulmonary Diseases
- Vascular Malformations and Hemangiomas
- Vascular Anomalies and Treatments
- Vascular anomalies and interventions
- Mechanical Circulatory Support Devices
- Metabolism, Diabetes, and Cancer
- Polyomavirus and related diseases
- Vasculitis and related conditions
- Growth Hormone and Insulin-like Growth Factors
- Respiratory and Cough-Related Research
- Thermal Regulation in Medicine
- Renal Transplantation Outcomes and Treatments
- Venous Thromboembolism Diagnosis and Management
- Central Venous Catheters and Hemodialysis
- Autism Spectrum Disorder Research
- Cardiovascular and Diving-Related Complications
- Diabetes Treatment and Management
University of Pennsylvania
2020-2024
Philadelphia University
2024
University of Florida
2020-2023
Pennsylvania Hospital
2018-2022
Florida College
2022
Temple University Hospital
2022
University of Pennsylvania Health System
2019-2020
California University of Pennsylvania
2020
Trinity College Dublin
2016
Pulmonary hypertension (PH), defined by a mean pulmonary artery pressure of >20 mm Hg, often presents with non-specific symptoms such as dyspnea and exercise intolerance, making it difficult to diagnose early before the onset right heart dysfunction. Therefore, testing can be great utility for clinicians who are evaluating patients an unclear etiology intolerance helping identify underlying mechanisms their disease. The presence PH is associated adverse clinical outcomes, distinct...
Air emboli are rare and often difficult to diagnose. Transesophageal echocardiography remains the most definitive method of diagnosis, but this is not feasible in emergencies. We present a case fatal air embolism setting hemodialysis with recent evidence pulmonary hypertension. The diagnosis was made by visualizing right ventricle using bedside point care ultrasound (POCUS). While POCUS routinely used for embolism, its accessibility makes it powerful yet practical emerging tool respiratory...
Belatacept is a novel T-cell costimulation blockade agent that has unresolved controversy in lung transplant recipients. been recognized as calcineurin sparing for solid organ recipients after reported success renal patients, despite limited evidence other We present the first case of recipient receiving Belatacept, combination with low dose inhibitor, who developed progressive multifocal leukoencephalopathy. While without inhibitor associated increased risk acute rejection recipients, its...
Takayasu’s arteritis is a rare large vessel vasculitis which can involve the pulmonary arteries and progress to artery (PA) stenosis with hypertension. We present case of Takayasu complicated by bilateral hypertension that resolved after PA stenting angioplasty. This demonstrates efficacy endovascular intervention sustained safety during 10 years follow-up.
Interstitial Lung Disease [ILD] patients requiring Invasive Mechanical Ventilation [IMV] for Acute Respiratory Failure [ARF] are known to have a poor prognosis. Few studies investigated determinants of outcomes and the utility trialing Non-Invasive Positive Pressure [NIPPV] prior IMV see if there any effect[s] on mortality or morbidity.A retrospective study was designed using at four different intensive care units within one health system. The primary objective determine differences in...
Proteus syndrome is a rare progressive multisystem disorder characterized by asymmetric, disproportionate overgrowth of bone, skin, and other tissue types. Molecular pathogenesis has been identified as somatic activating mutations the AKT1 gene. The presentation exceptionally variable. Respiratory complications include emphysematous lung disease predisposition to pulmonary emboli, latter which significant source mortality. Pulmonary hypertension due longstanding hypoxic well chronic...
Acute respiratory distress syndrome has not been a described complication of hypothermia. Causes hypothermia are commonly associated with alcohol abuse and infection, both which could lead to acute syndrome. We present case severe complicated by in young immunocompetent male treated successfully mechanical intubation venovenous extracorpeal membrane oxygenation. Risk factors for known causes included witnessed aspiration event RSV pneumonia. On review the literature, found cause pulmonary...
Abstract Background Interstitial lung disease (ILD) patients requiring invasive mechanical ventilation (IMV) for acute respiratory failure (ARF) are known to have a poor prognosis. Few studies investigated determinants of outcomes and the utility trialing non-invasive positive pressure (NIPPV) prior IMV see if there any effect(s) on mortality or morbidity. Methods We designed retrospective study using at four different intensive care units within one health system. Our primary objective was...
Abstract Background Interstitial lung disease (ILD) patients requiring invasive mechanical ventilation (IMV) for acute respiratory failure (ARF) are known to have a poor prognosis. Few studies investigated determinants of outcomes and the utility trialing non-invasive positive pressure (NIPPV) prior IMV see if there any effect(s) on mortality or morbidity.Methods We designed retrospective study using at four different intensive care units within one health system. Our primary objective was...