A5066439254- Esophageal and GI Pathology
- Gastrointestinal disorders and treatments
- Gastroesophageal reflux and treatments
- Inflammatory Bowel Disease
- Gastrointestinal Bleeding Diagnosis and Treatment
- Helicobacter pylori-related gastroenterology studies
- Foreign Body Medical Cases
- Intestinal Malrotation and Obstruction Disorders
- Autoimmune and Inflammatory Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Gallbladder and Bile Duct Disorders
- Pancreatitis Pathology and Treatment
- Eosinophilic Esophagitis
- Amoebic Infections and Treatments
- Congenital Diaphragmatic Hernia Studies
- Elbow and Forearm Trauma Treatment
- Clinical Nutrition and Gastroenterology
- Abdominal Surgery and Complications
- Bone fractures and treatments
- Diagnosis and treatment of tuberculosis
- Immunodeficiency and Autoimmune Disorders
- Microscopic Colitis
- Anesthesia and Neurotoxicity Research
- Inflammatory Myopathies and Dermatomyositis
- Restraint-Related Deaths
Sheffield Children's Hospital
2010-2024
Shaare Zedek Medical Center
2023
Hebrew University of Jerusalem
2023
Sheffield Children's NHS Foundation Trust
2021
Peterborough City Hospital
2001
Abstract Paediatric‐onset inflammatory bowel disease (IBD) has an enormous impact on healthcare systems as it translates to a lifetime of healthcare. Since the approval anti‐tumour necrosis factor‐alpha agents, become evident that in long journey paediatric IBD, there is absolute need for more treatment options. Emerging evidence from adult literature suggests upadacitinib effective and safe; however, data are scarce. We present two adolescents with highly refractory Crohn's disease. One...
Endoscopy is integral to the diagnosis and management of many gastrointestinal problems in children. Recently number endoscopic procedures performed has increased considerably worldwide raising questions about their appropriateness cost-efficacy.The aim study was determine diagnostic yield (the likelihood that a procedure or test will provide information required establish diagnosis) endoscopy paediatric population large tertiary referral centre terminal ileum intubation (TII) rate...
Endoscopic balloon dilatation (EBD) has been shown to be effective and safe in adults with stricturing Crohn disease (CD) yet pediatric data is sparse. We aimed assess efficacy safety of EBD CD.International collaboration included 11 centers from Europe, Canada, Israel. Recorded patient demographics, stricture features, clinical outcomes, procedural adverse events, need for surgery. Primary outcome was surgery-free over 12 months secondary outcomes were response events.Eighty-eight...
Iatrogenic viscus perforation in pediatric gastrointestinal endoscopy (GIE) is a very rare, yet potentially life-threatening event. There are no evidence-based recommendations relating to immediate post-procedure follow-up identify perforations and allow for timely management. This study aims characterize the presentation of children with post-GIE better rationalize recommendations.Retrospective based on unrestricted pooled data from centers throughout Europe, North America, Middle East...
Abstract Background Percutaneous endoscopic gastrostomy is commonly used for enteral nutritional access, but gastrocutaneous fistulae (GCF) may persist after tube removal, posing clinical challenges. The use of closure devices, including over-the-scope clips (OTSC), has shown promise in managing non-healing fistulae, although data the pediatric population are limited. Methods A retrospective multicenter study analyzed patients who underwent GCF following removal. Data from seven centers...
Ileo-colonoscopy (IC) can be technically challenging because of unpredictable colonoscope loop formation. Aims this study were to assess the risk formation and attempt understand which factors likely predispose subtype loop.Prospective conducted on children referred for an IC at Sheffield Children's Hospital. Presence type was objectively assessed using magnetic endoscope imaging tool.Three hundred procedures prospectively evaluated. Only 9% paediatric ICs loop-free. Alpha loops most common...
Abstract Background Endoscopic balloon dilatation (EBD) is an effective management strategy in stricturing Crohn’s disease (CD). While adult studies showed a high success rate of improved symptoms and avoiding surgical intervention, very little has been published children. We thus present multi-centre retrospective cohort study EBD paediatric CD from 9 centres affiliated with the Paediatric IBD Porto group ESPGHAN. Methods Demographics, imaging, serological data, clinical indices (including...
<h3>Introductions</h3> Over The Scope Clips (OTSC)® have developed valuable indications in adult endoscopy. These include: non-variceal gastrointestinal (GI) bleeding, anastomotic closure of fistulae such as gastro-cutaneous and post-gastrostomypersistent closure. Different clip sizes are available, the smallest being 8.5–9.8 mm diameter with its loading device on tip endoscope increasing intubation to 14.6 mm. This may present challenges terms size patient whom it might be used. OTSC®...