A5034844489- Gut microbiota and health
- Berberine and alkaloids research
- Clostridium difficile and Clostridium perfringens research
- Liver Disease Diagnosis and Treatment
- RNA Interference and Gene Delivery
- RNA modifications and cancer
- Dendrimers and Hyperbranched Polymers
- Metabolism, Diabetes, and Cancer
- Antimicrobial agents and applications
- Obesity, Physical Activity, Diet
- Growth Hormone and Insulin-like Growth Factors
- Nutritional Studies and Diet
- Dietary Effects on Health
- Diabetes Treatment and Management
- Epigenetics and DNA Methylation
- Pancreatitis Pathology and Treatment
- Ferroptosis and cancer prognosis
- Ginseng Biological Effects and Applications
- Advanced Glycation End Products research
- Thyroid Cancer Diagnosis and Treatment
- Cancer Cells and Metastasis
- Lipid metabolism and disorders
- Biochemical effects in animals
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Healthcare and Venom Research
Ningxia Medical University
2024
Peking University
2024
Air Force Medical University
2015-2023
Xijing Hospital
2015-2023
The Royal Melbourne Hospital
2021
The University of Melbourne
2021
Shaanxi Coal Chemical Industry Technology Research Institute
2020
University of Science and Technology of China
2006-2007
Berberine and Bifidobacterium have been reported to improve glucose tolerance in people with hyperglycemia or other metabolic disorders. This study aimed assess the hypoglycemic effect regulation of gut microbiota caused by berberine possible additive benefits their combination.
Malnutrition poses a significant public health challenge, particularly as the global population ages. However, there is notable lack of comprehensive literature analyzing burden malnutrition among elderly. Data on nutritional deficiencies indicators-prevalence, incidence, and disability-adjusted life years (DALYs)-for individuals aged 70 older were extracted from Global Burden Diseases, Injuries, Risk Factors Study (GBD) database 1990 to 2021. The estimated annual percentage change (EAPC)...
Emerging studies have focused the association between non-alcoholic fatty liver disease (NAFLD) and risk of type 2 diabetes mellitus (T2DM) but results were inconsistent. In addition, few put focus on NAFLD prediabetes. We aimed to investigate whether diagnosed by ultrasonography could predict future T2DM prediabetes in Chinese population. The population-based cohort study held Xi'an, Northwestern China, was based China National Diabetes Metabolic Disorders Survey. During a follow-up 5...
Abstract Background Triple-negative breast cancer (TNBC) represents a highly aggressive subset of malignancies characterized by its challenging clinical management and unfavorable prognosis. While TFAP2A, member the AP-2 transcription factor family, has been implicated in maintaining basal phenotype cancer, precise regulatory role TNBC remains undefined. Methods In vitro assessments cell growth migratory potential were conducted using MTS, colony formation, EdU assays. Quantitative PCR was...
The aim of our study is to establish the reference intervals (RIs) thyroid hormones in a previously iodine-deficient area but presently more than iodine-adequate Western China, and also investigate factors which affect function. cross-sectional conducted Xi'an, was based on 2007-2008 China National Diabetes Metabolic Disorders Survey. Among 1286 participating adults, 717 were finally included as population. Thyrotropin (TSH), total triiodothyronine (T3), free (FT3), thyroxine (T4), (FT4),...
Abstract Aims Glycated albumin (GA) is a biomarker for short‐term (2–3 weeks) glycaemic control. However, the predictive utility of GA diabetes and prediabetes largely uncharacterised. We aimed to investigate relationships baseline serum levels with incident prediabetes. Methods This was longitudinal cohort study involving 516 subjects without or at baseline. Blood glucose were observed during follow‐up. Hazard ratios (HRs) 95% confidence intervals (CIs) calculated using COX proportional...
Abstract Background To compare glycemic control in Chinese patients with type 2 diabetes mellitus (T2DM) whose blood glucose levels were inadequately controlled oral antidiabetic drugs after beinaglutide alone or combined insulin glargine (IGlar). Methods In this 16‐week multicenter, randomized clinical trial, 68 participants randomly received IGlar for 8 weeks, then the two combination weeks. The primary outcomes proportion of individuals achieving their target and change variability as...
Objective: We aimed to examine whether meal patterns, as well energy intake from three main meals and snacks, were associated with incident hypertension. Methods: included 12 995 participants aged 18–59 years the China Health Nutrition Survey in final analysis. Dietary was assessed using weighing methods combination 24-h food records. Cox proportional hazards regression models used association of different Results: During a mean follow-up 11.2 years, 4766 new hypertension cases documented....
Objective: The objective of this study was to evaluate the home food environment elderly in Beijing and analyze its association with body mass index (BMI) elderly, as well provide recommendations for improving elderly. Methods: This conducted Beijing, China, 2019. participants were 1764 individuals aged 65 80, recruited from 12 communities through a multistage stratified random sampling method. involved use questionnaire surveys gather data on participants’ demographics, availability various...
Objective To investigate the characteristics of components metabolic syndrome in young men with hypogonadotropic hypogonadism (HH). Methods A total 35 treatment–naive male patients (19.3±5.0) yrs) HH were included group, and 22 healthy similar age body mass index (BMI) recruited control group from June 2013 to September 2014. Serum sex hormones, follicle – stimulating hormone (FSH), luteinizing (LH) serum lipids levels measured fasting blood samples. Plasma glucose insulin taken...
Objective To investigate the prevalence and related factors of exocrine pancreatic insufficiency in patients with diabetes mellitus (DM). Methods A total 150 including 23 type 1 (T1DM) 127 2 (T2DM), 48 healthy controls from Xijing Hospital were enrolled this investigation between March 2009 June 2010. The clinical laboratorial parameters such as age, gender, body mass index (BMI), course, diabetic microvascular complications, glycated hemoglobin A1c (HbA1c) recorded. Stool samples...
Abstract Background APC2 is as a homolog of adenomatous polyposis coli (APC) that has comparable functions in cancer, and located on chromosome 19p13.3. It an important signaling pathway protein many cancers diseases. For example, ovarian serves tumor suppressor through the induction WNT pathway, inhibiting invasion growth. In colorectal was shown to be for metastasis. present study, regulatory cooperates with microRNA bidirectional regulation induce phenotypic changes cancer. Methods...