- Functional Brain Connectivity Studies
- Neuroendocrine regulation and behavior
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Health, Environment, Cognitive Aging
- Advanced MRI Techniques and Applications
- Mental Health Research Topics
- Autism Spectrum Disorder Research
- Child and Adolescent Psychosocial and Emotional Development
- Personality Disorders and Psychopathology
- Radiomics and Machine Learning in Medical Imaging
- Child Development and Digital Technology
- Neural and Behavioral Psychology Studies
- Psychology of Moral and Emotional Judgment
- Behavioral and Psychological Studies
- Evolutionary Psychology and Human Behavior
- Obsessive-Compulsive Spectrum Disorders
- Attention Deficit Hyperactivity Disorder
- Action Observation and Synchronization
- Meta-analysis and systematic reviews
- Identity, Memory, and Therapy
- Deception detection and forensic psychology
- Face Recognition and Perception
- Impact of Technology on Adolescents
- Genetic Associations and Epidemiology
- Advanced Neuroimaging Techniques and Applications
Erasmus University Rotterdam
2019-2024
Development Research Center
2021-2024
Leiden University
2012-2023
The Ohio State University
2021
University of Wisconsin–Madison
2021
Wellcome Centre for Human Neuroimaging
2021
University College London
2012-2021
The University of Texas at Austin
2021
Brain (Germany)
2021
Leiden University Medical Center
2013-2020
Performing quality control to detect image artifacts and data-processing errors is crucial in structural magnetic resonance imaging, especially developmental studies. Currently, many studies rely on visual inspection by trained raters for control. The subjectivity of these manual procedures lessens comparability between studies, with growing study sizes increasingly time consuming. In addition, both inter-rater as well intra-rater variability high may lead inclusion poor scans exclusion...
Background Deficits in empathy are reported autism spectrum disorders (ASD) and also underlie antisocial behavior of individuals with conduct disorder callous‐unemotional traits (CD/CU+). Many studies suggest that ASD typically impaired cognitive aspects empathy, CD/CU+ affective aspects. In the current study, we compared neural correlates between youth CD/CU+. Methods Functional magnetic resonance imaging (fMRI) was used to assess boys ( N = 23), developing (TD) 33), aged 15–19 years. Angry...
Although the majority of our social interactions are with people we know, few studies have investigated neural correlates sharing valuable resources familiar others. Using an ecologically valid research paradigm, this functional magnetic resonance imaging study examined prosocial and selfish behavior in real-life friends disliked peers young adults. Participants (N = 27) distributed coins between themselves another person, where they could make choices that maximized their own gains or...
Abstract Psychopathy is a serious psychiatric phenomenon characterized by pathological constellation of affective (e.g., callous, unemotional), interpersonal manipulative, egocentric), and behavioral impulsive, irresponsible) personality traits. Though amygdala subregional defects are suggested in psychopathy, the functionality connectivity different subnuclei typically disregarded neurocircuit‐level analyses psychopathic personality. Hence, little known how networks may contribute to...
Youth of today grow up in a digital social world but the effects on well-being and brain development remain debated. This study tracked longitudinal associations between structural development, media use mental well-being. The demonstrated two pathways heterogeneity development. First, adolescents who used more than their peers showed higher baseline cortical thickness lateral prefrontal cortex (PFC) medial PFC; stronger decreases PFC temporal parietal junction. In contrast, with lower...
Research suggests that individuals with conduct disorder (CD) are marked by social impairments, such as difficulties in processing the affective reactions of others. Little is known, though, about how they make decisions during interactions response to emotional expressions In this study, we therefore investigated neural mechanisms underlying fairness communicated emotions others aggressive, criminal justice-involved boys CD (N = 32) compared typically developing (TD) 33), aged 15-19 years....
Abstract Alcohol consumption is commonly initiated during adolescence, but the effects on human brain development remain unknown. In this multisite study, we investigated longitudinal associations of adolescent alcohol use and morphology. Three cohorts in Netherlands (BrainScale n = 200, BrainTime 239 a subsample Generation R study 318) typically developing participants aged between 8 29 years were included. Adolescent was self‐reported. Longitudinal neuroimaging data collected for at least...
During adolescence, peers take on increasing importance, while social skills are still developing. However, how emotions of influence decisions during that age period is insufficiently known. We therefore examined the effects three different emotional responses (anger, disappointment, happiness) about fairness in a sample 156 adolescents aged 12-17 years. Participants received written from version Dictator Game to previous unfair offer. Adolescents reacted with more generous offers after...
The current study presents a novel experimental design to examine how real-life peer relationships modulate altruistic punishment of bullies and compensation victims after observed ostracism. Twenty-four participants (age 20) were invited an ex
Little is known about how emotions expressed by others influence social decisions and associated brain responses in autism spectrum disorders (ASD). We investigated the neural mechanisms underlying fairness response to explicitly of boys with ASD typically developing (TD) boys. Participants adjusted their allocation behavior but reacted less unfair than TD controls happiness. also found reduced precental gyrus versus group when receiving happy angry reactions autistic traits were positively...
Task-related functional MRI (fMRI) studies need to be properly powered with an adequate sample size reliably detect effects of interest. But for most fMRI studies, it is not straightforward determine a proper using power calculations based on published effect sizes. Here, we present alternative approach estimation empirical Bayesian updating. First, this method provides estimate the required existing data from similar task and region Using researchers can plan their research project, report...
Reflecting evidence on Callous-Unemotional (CU) traits (e.g., lack of empathy and guilt, shallow affect), the DSM-5 added a categorical CU-based specifier for Conduct Disorder (CD), labeled 'with Limited Prosocial Emotions' (LPE). Theory prior work suggest that CD youths with without LPE will likely differ in neural processing negative socioemotional content. This proposition, however, is mainly derived from studies employing related, yet distinct, operationalizations CU dimensional...
We tested whether adolescents with daily high identity uncertainty showed differential structural brain development across adolescence and young adulthood. Participants (N = 150, MageT1 15.92 years) were followed three waves, covering 4 years. Self-reported educational data of lateral prefrontal cortex (lPFC)/anterior cingulate (ACC), medial PFC, nucleus accumbens (NAcc) was collected waves. All hypotheses pre-registered. Latent class growth analyses confirmed 2 subgroups: an synthesis...
Many workflows and tools that aim to increase the reproducibility replicability of research findings have been suggested. In this review, we discuss opportunities these efforts offer for field developmental cognitive neuroscience, in particular neuroimaging. We focus on issues broadly related statistical power flexibility transparency data analyses. Critical considerations relating include challenges recruitment testing young populations, how value studies with small samples, working...
Abstract Performing quality control to detect image artifacts and data-processing errors is crucial in structural magnetic resonance imaging, especially developmental studies. Currently, many studies rely on visual inspection by trained raters for control. The subjectivity of these manual procedures lessens comparability between studies, with growing study sizes increasingly time consuming. In addition, both inter-rater as well intra-rater variability high may lead inclusion poor scans...
<h3>Aims</h3> Adolescence is the transitional stage of physical, psychological and social development between childhood adulthood. The brain, network brain regions involved in understanding other people9s mental states emotions, undergoes structural functional changes during adolescence. This includes dorsomedial prefrontal cortex (DMPFC), anterior temporal (ATC), temporoparietal junction (TPJ) posterior superior sulcus (pSTS). timing this coincides with puberty, it hypothesised that...