A5103267969- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Cardiac Valve Diseases and Treatments
- Heart Failure Treatment and Management
- Cardiovascular Disease and Adiposity
- Heart Rate Variability and Autonomic Control
- Antiplatelet Therapy and Cardiovascular Diseases
- Atrial Fibrillation Management and Outcomes
- Cardiovascular and exercise physiology
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiac electrophysiology and arrhythmias
- Cardiac, Anesthesia and Surgical Outcomes
- Diabetes Treatment and Management
- Heart rate and cardiovascular health
- Cardiovascular Effects of Exercise
- Lipoproteins and Cardiovascular Health
- Bone Metabolism and Diseases
- Cardiac Structural Anomalies and Repair
- Cardiovascular Health and Disease Prevention
- Blood Pressure and Hypertension Studies
- Mechanical Circulatory Support Devices
- Acute Kidney Injury Research
- Cardiac Arrhythmias and Treatments
Copenhagen University Hospital
2005-2024
Frederiksberg Hospital
2005-2024
Gentofte Hospital
2014-2023
Bispebjerg Hospital
2014-2023
University of Copenhagen
2002-2022
University of Southern Denmark
2002-2015
Odense University Hospital
2015
Aarhus University Hospital
2005-2014
Aarhus University
2014
Rigshospitalet
1998-2009
Recent studies have suggested that higher body mass index (BMI) is associated with improved prognosis in chronic heart failure (CHF). The adipocytokine adiponectin inversely BMI, and healthy subjects, low a predictor of mortality. In prospective study, we therefore evaluated the association between plasma levels mortality among patients CHF.In 195 CHF (age 69.3+/-10.2 years, BMI 27.3+/-5.2 kg/m2, left ventricular ejection fraction 30+/-8.9%, mean+/-SD), N-terminal pro brain natriuretic...
Background: The optimal timing of invasive coronary angiography (ICA) and revascularization in patients with non-ST-segment elevation acute syndrome is not well defined. We tested the hypothesis that a strategy very early ICA possible within 12 hours diagnosis superior to an performed 48 72 terms clinical outcomes. Methods: Patients admitted suspicion Capital Region Copenhagen, Denmark, were screened for inclusion VERDICT trial (Very Early Versus Deferred Invasive Evaluation Using...
Two-dimensional strain echocardiography detects early signs of left ventricular dysfunction; however, it is unknown whether myocardial analysis at rest in patients with suspected stable angina pectoris predicts the presence coronary artery disease (CAD).In total, 296 consecutive clinically pectoris, no previous cardiac history, and normal ejection fraction were included. All examined by 2-dimensional echocardiography, exercise ECG, angiography. was performed 3 apical projections. Peak...
Abstract Aims To assess whether implementation of the 2019 European Society Cardiology (ESC)/European Atherosclerosis (EAS) dyslipidaemia guidelines observed between 2020 and 2021 improved 2022 in SANTORINI study. Methods results Patients with high or very cardiovascular (CV) risk were recruited across 14 countries from March to February 2021, 1-year prospective follow-up until May 2022. Lipid-lowering therapy (LLT) ESC/EAS risk-based low-density lipoprotein (LDL) cholesterol (LDL-C) goal...
BackgroundAdiponectin is viewed as an insulin-sensitizing hormone with anti-inflammatory effects. In accordance, plasma adiponectin decreased in metabolic disorders including type 2 diabetes mellitus (T2DM). However, spite of the apparently beneficially effects, recent data from large prospective studies have consistently linked high levels increased cardiovascular (CV) disease and mortality, thus questioning positive view on adiponectin. Accordingly, we investigated relationship between...
Neutrophil gelatinase-associated lipocalin (NGAL) is a glycoprotein stored in granules of neutrophil leukocytes participating inflammatory and atherosclerotic processes possibly plaque rupture. Despite the putative role NGAL atherosclerosis acute myocardial infarction, human studies plasma are still limited.We prospectively followed 5599 randomly selected men women from community fourth Copenhagen Heart Study. Plasma was measured at study entry. Participants were for 10 years. During...
Objectives: We aimed to determine the prevalence of echocardiographic abnormalities and their relation clinical characteristics cardiac symptoms in a large, contemporary cohort patients with type 2 diabetes. Results: A total 1030 diabetes participated. Echocardiographic were present 513 (49.8%) patients, mainly driven by high diastolic dysfunction 178 (19.4%), left ventricular hypertrophy 213 (21.0%) atrial enlargement, 200 (19.6%). The increased markedly age from 31.1% youngest group...
Color tissue Doppler imaging M-mode through the mitral leaflet is an easy and precise method to estimate all cardiac time intervals from 1 cycle thereby obtain myocardial performance index (MPI). However, prognostic value of MPI assessed by color in patients with ST-segment-elevation infarction (MI) unknown.In total, 391 were admitted MI, treated primary percutaneous coronary intervention, examined echocardiography a median 2 days after MI. Outcome was according death (n=33), hospitalization...
Global longitudinal systolic strain (GLS) has recently been demonstrated to be a superior prognosticator conventional echocardiographic measures in patients after myocardial infarction (MI). The aim of this study was evaluate the prognostic value regional deformation comparison GLS, echocardiography and clinical information.In total 391 were admitted with ST-Segment elevation (STEMI), treated primary percutaneous coronary intervention subsequently examined by echocardiography. All tissue...
Atrial fibrillation (AF) is the most common arrythmia following ST-segment elevation myocardial infarction (STEMI) and can lead to stroke other heart-related diseases. This study aimed determine prognostic value of left atrial (LA) strain, obtained by speckle tracking echocardiography (STE), in predicting incident AF outcomes STEMI treated with primary percutaneous coronary intervention (pPCI).This prospective comprised 392 patients pPCI. The had an performed at a median two days after their...
To determine if colour tissue Doppler imaging (TDI) performed at rest in patients with suspected stable angina pectoris (SAP) is able to predict the presence of significant coronary artery disease (CAD). This study comprises 296 consecutive clinically SAP, no previous cardiac history, and a normal ejection fraction. All were examined by TDI, exercise electrocardiogram (ECG), angiography (CAG). Regional longitudinal systolic (s′), early diastolic (e′), late (a′) myocardial velocities measured...