A5066713540- Reconstructive Surgery and Microvascular Techniques
- Reconstructive Facial Surgery Techniques
- Facial Rejuvenation and Surgery Techniques
- Facial Nerve Paralysis Treatment and Research
- Tracheal and airway disorders
- Head and Neck Surgical Oncology
- Body Image and Dysmorphia Studies
- Voice and Speech Disorders
- Bone Tumor Diagnosis and Treatments
- Facial Trauma and Fracture Management
- Trauma Management and Diagnosis
- Head and Neck Cancer Studies
- Prenatal Screening and Diagnostics
- Organ and Tissue Transplantation Research
- Nasal Surgery and Airway Studies
- Cleft Lip and Palate Research
- Transplantation: Methods and Outcomes
- LGBTQ Health, Identity, and Policy
- Surgical site infection prevention
- Sinusitis and nasal conditions
- Oral and Maxillofacial Pathology
- Nerve Injury and Rehabilitation
- Salivary Gland Tumors Diagnosis and Treatment
- Congenital Anomalies and Fetal Surgery
- Surgical Sutures and Adhesives
University of California, San Francisco
2016-2025
University of California San Francisco Medical Center
2013-2023
Cleveland Clinic
2004-2013
University of California, Los Angeles
2007-2013
University of Toronto
2013
Cleveland Clinic Lerner College of Medicine
2012
Case Western Reserve University
2012
Indiana University – Purdue University Indianapolis
2012
Stanford University
2009
Stanford Medicine
2009
Case 2-A day old girl was referred, having developed cyanotic episodes not associated with feeding at 12 hours.Catheters were easily passed into the oropharynx through both nostrils.She prescribed 0.5% ephedrine nose drops for evident nasal congestion, but her condition deteriorated so withdrawn.Radiological findings normal, and examination under anaesthesia showed normal airways except mucosal congestion in nose.The passages dilated up to 14 French gauge.Post- operatively regular suction...
Identification of human satellite cells that fulfill muscle stem cell criteria is an unmet need in regenerative medicine. This hurdle limits understanding how closely properties are conserved among mice and humans hampers translational efforts regeneration. Here, we report PAX7 exist at a consistent frequency 2–4 cells/mm fiber muscles the trunk, limbs, head. Xenotransplantation into 50–70 fiber-associated, or 1,000–5,000 FACS-enriched CD56+/CD29+ led to stable engraftment formation...
Investigation of human muscle regeneration requires robust methods to purify and transplant stem progenitor cells that collectively constitute the satellite cell (HuSC) pool. Existing approaches have yet make HuSCs widely accessible for researchers, as a result research has advanced slowly. Here, we describe predictable HuSC purification process is effective each skeletal tested development storage protocols transplantation models in dystrophin-deficient wild-type recipients. Enzymatic...
Objectives/Hypothesis Machine learning (ML) is a type of artificial intelligence wherein computer learns patterns and associations between variables to correctly predict outcomes. The objectives this study were 1) use ML platform identify factors important in predicting surgical complications patients undergoing head neck free tissue transfer, 2) compare outputs traditionally employed logistic regression models. Study Design Retrospective cohort study. Methods Using dataset 364 consecutive...
Gender-affirming facial surgery (GFS) is pursued by transgender individuals who desire features that better reflect their gender identity. Currently, there are a few objective guidelines to justify and facilitate effective surgical decision making.
Locally advanced, unresectable basal cell carcinoma (LA BCC) can be treated with radiation therapy (RT), but locoregional control (LRC) rates are unsatisfactory. Vismodegib is a hedgehog pathway inhibitor (HPI) active in BCC that may radiosensitize BCC. We evaluated the combination of vismodegib and RT for patients LA
Objectives/Hypothesis: To describe the clinical entity and therapeutic challenges of bisphosphonate-related osteonecrosis jaws (BRONJ). The use vascularized bone grafts for reconstruction mandible in extensive BRONJ is proposed. Study Design: Multi-institutional retrospective review. Methods: Patients undergoing with after segmental resection were evaluated. Mandible was only performed on patients intractable pain, fistulae, or pathologic fracture failure comprehensive conservative therapy....
Donor site morbidity is an important consideration in the overall decision-making algorithm for fasciocutaneous free flap reconstruction of head and neck.A retrospective case series was conducted donor complications occurring within 30 days surgery among 226 consecutive anterolateral thigh (ALT) or radial forearm (RFFF) microvascular tissue transfers performed by multiple reconstructive surgeons between 2005 2010.A greater number occurred patients undergoing RFFF versus ALT flaps (40; 35.4%;...
Study Design: Retrospective cohort study. Objective: To (1) assess post-operative quality of life (QOL) and functional outcomes fibula free flap (FFF) donor sites, (2) examine the incidence claw toe deformities (CTDs) following FFF harvest, (3) effect flexor hallicus longus (FHL) muscle preservation on CTDs. Methods: Patients aged 18 years or older at least 6 months from reconstructive surgery completed Manchester–Oxford Foot Questionnaire (MOXFQ)and Short-form 36 (SF-36) Questionnaire. The...
This study investigates the role of social determinants health (SDOH) in accessing gender-affirming facial surgery (GFS) at a single tertiary care institution. By examining demographic, socioeconomic, and profiles patients, this seeks to characterize barriers pursuing GFS identify possible areas for growth providing equitable care. A mixed-methods approach was employed, including retrospective chart review all previous patients institution semi-structured interviews. Data collected included...
Objective: To identify the incidence of hardware and bone-healing complications in patients who underwent locking mandibular reconstruction plate (LMRP) fixation vascularized bone grafts for segmental defects.Design: Case series.Setting: Academic tertiary
To compare the long-term cosmesis of Dermabond (octyl-2-cyanoacrylate) and traditional skin sutures among patients undergoing primary cleft lip +/- palate repair.Eleven underwent photographic analysis following repair, including use Dermabond. Eleven age-matched controls who repair with suture closure served as controls. Cosmesis was assessed by 3 blinded plastic surgeons using a visual analogue scale (VAS) Hollander Wound Evaluation Scale (HWES).The overall mean VAS score for treated...
Background Extirpation of aggressive parotid or cutaneous facial tumors often involves nerve sacrifice and the creation a large soft-tissue defect. We describe method for single-stage reconstruction during radical parotidectomy to restore form function without additional morbidity. Methods conducted review immediate reconstruction/reanimation defects with use anterolateral thigh (ALT) fat fascia flaps contouring, orthodromic temporalis tendon transfer (OTTT), cable grafting nerve, lata lower...
To describe a surgical technique for total palatomaxillary and orbital reconstruction using fibula osteocutaneous free flap in layered fashion. Case series from tertiary care facial plastic reconstructive practice including patients with postextirpative Brown 3a 3b orbitopalatomaxillary defects undergoing immediate microvascular reconstruction. Application of the to composite maxillary permits single-stage, optimal contiguous orbitomaxillary defects, reconstitution midface 3-dimensional...
Objective To further delineate the anatomy of motor nerve to vastus lateralis (MNVL) in context its use as a possible interpositional graft facial rehabilitation.Methods Twelve fresh human cadaveric thighs were dissected investigate anatomic location and branching pattern MNVL muscle.Results There 3 6 primary branches (mean, 4.4) supplying lateralis. The mean branch length was 93.8 mm (range, 51-196 mm), each had 2.3 subsequent branches. 2 larger caliber (>2 diameter) proximal distal muscle....
Minimizing morbidity when performing free flap reconstruction of the head and neck is important in overall reconstructive paradigm.To examine indications success rates tissue transfer using small-caliber facial recipient vessels minimal access incisions.Retrospective medical record review patients with defects undergoing from May 2010 to June 2013 at 2 tertiary care academic centers.Free approaches.Postoperative complications, including failure, requirement for revision surgery, nerve...
Bicycling is an increasingly common activity in the United States that often associated with fall injuries to head and face. Although helmets lessen injury, their role reducing facial less clear; therefore, it important understand protective capacity for face current helmet design.To estimate conventional bicycle helmet's association rate of injury after crashes.This retrospective cohort study accessed records from January 1, 2010, December 31, 2014, National Trauma Databank, which collects...