A5069929992- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Respiratory and Cough-Related Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Pediatric health and respiratory diseases
- Inhalation and Respiratory Drug Delivery
- Drug-Induced Adverse Reactions
- Respiratory Support and Mechanisms
- Food Allergy and Anaphylaxis Research
- Air Quality and Health Impacts
- Nutritional Studies and Diet
- Dermatology and Skin Diseases
- Urticaria and Related Conditions
- Carcinogens and Genotoxicity Assessment
- Nutrition and Health Studies
- Obesity, Physical Activity, Diet
- Fatty Acid Research and Health
- Cystic Fibrosis Research Advances
- Health, Environment, Cognitive Aging
- Birth, Development, and Health
- Building energy efficiency and sustainability
- Neonatal Respiratory Health Research
- Toxic Organic Pollutants Impact
- Pregnancy and Medication Impact
- Effects and risks of endocrine disrupting chemicals
Copernicus Memorial Hospital
2009-2024
Medical University of Lodz
2008-2024
Nofer Institute of Occupational Medicine
2021-2023
Wojewódzki Szpital Specjalistyczny Nr 2
2004-2009
Vitamin D plays an important role in inflammatory responses after antigen exposure. Interleukin-23 (Il-23) promotes Il-17-dependent inflammation during Pseudomonas aeruginosa (P. aeruginosa) pulmonary infection. We aimed to compare the ability of calcitriol and cholecalciferol modulate response CF airways infected with P. aeruginosa.This was a randomized, placebo-controlled, double-blind, cross-over trial. Twenty-three patients (aged 6-19), chronically by were randomly assigned to: group...
To date, some studies suggest that passive smoking (PS) may be an important determinant of FeNO levels in children but sill there is a need investigations using objective methods PS exposure. The aim our study was to examine the effect PS, measured by urine cotinine levels, on and lung function (FEV1) allergic non-allergic asthmatic children. It prospective, non-interventional study. 140 children, aged 4–17, newly diagnosed with asthma were recruited into two groups (exposed group, unexposed...
To specify clinical and immunological parameters of the mechanisms, which may lead to development persistent asthma, or regression disease symptoms.Eighty children with childhood diagnosed in past by using modified Asthma Predicted Index (mAPI), were divided into two groups: remission group group. There 3 study visits (baseline, at 6 mo, 12 mo). Clinical asthma was defined as absence symptoms for least mo without treatment. The patients could switch from one another during follow-up....
Objective. We hypothesized that, in our REPRO_PL cohort, exposure to indoor allergens and lifestyle factors early life are associated with risk of asthma, atopic dermatitis, allergic rhinitis at ten years age. Methods. only examined children who had lived the same house from birth. Children’s tobacco smoke was assessed based on cotinine levels urine. House dust samples were collected. Results. Higher Fel d1 concentration significantly higher developing asthma age 10 (95% CI,10.87 20.93; p...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Brzozowska A, Majak P, Jerzyńska J, et al. Original articleExhaled nitric oxide correlates with IL-2, MCP-1, PDGF-BB and TIMP-2 in exhaled breath condensate of children refractory asthma. Advances Dermatology Allergology/Postępy Dermatologii i Alergologii. 2015;32(2):107-113. doi:10.5114/pdia.2014.40953. APA Brzozowska, A., Majak, P., Jerzyńska, J., Smejda, K., Bobrowska-Korzeniowska, M., & Stelmach, W. (2015)....
Microelements and vitamins are believed to have immunomodulatory effects. The aim of the study was establish role antioxidants (vitamins A, E, D) microelements such as copper (Cu), selenium (Se), zinc (Zn) levels in allergic diseases schoolchildren. uses a cohort 80 children (40 with 40 without allergy/asthma diagnosis) aged 9 12 years recruited for Polish Mother Child Cohort Study. At nine twelve old, were tested microelement vitamin content health status (including skin-prick test...
Markers of exhaled breath condensate (EBC) correlate with lung function impairment, airway remodeling and different aspects the disease such as exercise-induced bronchoconstriction (EIB). Aim study was to determine cytokine profile in EBC children asthma after an exercise treadmill challenge order obtain clinically useful information about mechanisms EIB; also, assess correlations between concentrations clinical characteristics patients.The population consisted 25 randomly selected children,...
Factors that facilitate the asthma diagnosis in children are still being investigated. We attempted to assess duration of a delay children, and we examined previously identified risk factors its occurrence together with pulmonary function test results such as spirometry specific airway resistance (sR(aw)) sought determine how measurement sR(aw) contributes children. This study was part Asthma Prevention Study Poland, which focused on increasing early detection community-based cohort. Data...
Olszowiec-Chlebna M, Majak P, Brzozowska A, Bobrowska-Korzeniowska Jerzynska J, Stelmach I. Effect of inhaled steroid and montelukast on clinical symptoms in children with newly diagnosed asthma: A pilot study.Pediatr Allergy Immunol 2010: 21: e687–e690.© 2010 John Wiley & Sons A/S There is a lack evidence for treatment asthma, they are based mainly expert opinion. This study was aimed at evaluating the effects corticosteroid (ICS) two different doses sodium lung function asthma. randomized,...
The FOXP3 transcription factor is a marker of regulatory T cells (Tregs), and essential in the process their activation proper expression by promoting immune homeostasis. To assess influence environment on development asthma, we hypothesized that our cohort, exposure to environmental factors associated with asthma risk children, levels vary incidence are negatively correlated developing asthma. This prospective study conducted Poland uses cohort 85 children (42 43 without diagnosis) aged 9...
Objectives: Polyunsaturated fatty acids (PUFAs) are involved both in immune system regulation and inflammation.The aim of this prospective study was to evaluate the association between maternal dietary intake PUFAs during pregnancy atopic dermatitis (AD) food allergy (FA) their children up 7-9 years age.Material Methods: The population consists 557 mother-child pairs from Polish Mother Child Cohort (REPRO_PL).Based on Food Frequency Questionnaire completed 20-24th weeks pregnancy, n-3 n-6 as...
We aimed to assess the real-life prevalence, patient profile, and clinical presentation of drug hypersensitivity NSAIDs in children after an incidence adverse event during treatment, verified by a challenge test.We included 56 children, aged 4-18 years, referred our allergy clinic due reaction treatment. Skin prick tests provocation test were performed all patients. Diagnostics for persistent urticaria performed.In patients suspected allergy, we proved NSAID 17 (30.1%). In 84.9% (n = 47)...
Background: The purpose of this study was to determine the clinical effect nedocromil sodium and its relationship with serum levels inflammatory mediators by monitoring lung function noninvasive markers airway inflammation, such as eosinophil blood counts; ECP, sIL‐2R, IL‐4 sICAM; total IgE. Anti‐inflammatory medications cause a reduction in decrease intensity hyperresponsiveness, improve symptoms asthma. Among available choices is sodium, which favored treatment asthmatic children due very...
There is no general agreement among investigators regarding the effect of specific immunotherapy (SIT) on T-cell reactivity. The aim this study was to investigate serum levels IL-1beta, IL-6, and TNF-alpha children with allergic asthma before after 3 12 months SIT. Additionally, SIT, we investigated bronchial hyperresponsiveness. secondary end points were clinical parameters. Thirty-two moderate house-dust mites (study group) 10 healthy (control participated in trial. At each visit blood...
Abstract Bisphenols are a group of chemical compounds widely used in the industry, e.g., production plastics, and as precursor epoxy resins. The three bisphenols investigated this study, namely A (BPA), F (BPF) S (BPS), seem to have endocrine activity same order magnitude. Thus, an exposure risk assessment was performed based on urinary concentrations these 150 urine samples 7-year-old children from Polish Mother Child Cohort Study (REPRO_PL). Samples were analyzed using high performance...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Bobrowska-Korzeniowska M, Brzozowska A, Jerzyńska J, Stelmach W, I. Usefulness of sRtot and Rint in bronchodilator testing the diagnosis asthma children. Advances Dermatology Allergology/Postępy Dermatologii i Alergologii. 2020;37(5):685-689. doi:10.5114/ada.2019.85631. APA Bobrowska-Korzeniowska, M., Brzozowska, A., Jerzyńska, J., Stelmach, W., & (2020). Alergologii, 37(5), 685-689....