A5062419805- Oral microbiology and periodontitis research
- Extracellular vesicles in disease
- Periodontal Regeneration and Treatments
- Bone and Dental Protein Studies
- MicroRNA in disease regulation
- Immune Response and Inflammation
- Oral and Maxillofacial Pathology
- Salivary Gland Disorders and Functions
- Reconstructive Surgery and Microvascular Techniques
- Dental Health and Care Utilization
- Tumors and Oncological Cases
- Immunotherapy and Immune Responses
- Oral and gingival health research
- Cell Adhesion Molecules Research
- T-cell and B-cell Immunology
- RNA Interference and Gene Delivery
- Dental Trauma and Treatments
- Dermatological and COVID-19 studies
- Hedgehog Signaling Pathway Studies
- dental development and anomalies
- COVID-19 diagnosis using AI
- HIV/AIDS oral health manifestations
- Dental Research and COVID-19
- Mesenchymal stem cell research
- Oral Health Pathology and Treatment
Nihon University
2018-2025
Exosomes are membrane vesicles that present in body fluids and contain proteins, lipids, microRNA (miRNA). Periodontal tissue examinations assess the degree of periodontal destruction according to probing depth (PD), clinical attachment loss (CAL), bleeding on probing, X-ray examinations. However, accurate evaluation prognosis periodontitis is limited. In this study, we collected saliva from patients before after initial therapy (IPT) compared changes parameters with components salivary...
The junctional epithelium and dental enamel adhere because of hemidesmosomes containing laminin 5 α6β4 integrin, which are important adhesion molecules in the internal basal lamina. Interleukin (IL)-1 is pathogenesis periodontal disease. IL-1β induces bone resorption by activating osteoclasts; however, its effects on epithelial cells remain to be clarified. Laminin β3, β4 focal kinase mRNA levels were higher after 1 h 3 stimulation with (1 ng/mL), IL-1β, type I α1, IV α1 collagen lower...
Laminin 5, type 4 collagen, and α6β4 integrin contribute to the formation of hemidesmosomes in epithelia periodontal tissues, which is critical for development maintenance dentogingival junction. As it not known whether TNF-α alters composition epithelial pericellular matrix, human gingival cells were cultured presence or absence TNF-α. Treatment with accelerated cell migration closure vitro wounds. These data indicate unexpectedly, that promotes matrix around enhances adhesion underlying...
適切な来院間隔によるサポーティブペリオドンタルセラピー(SPT)の実施は,歯周炎の再発防止と歯周組織の安定の維持に有効である。新型コロナウイルス感染症(COVID-19)の蔓延に伴い,歯科医療機関への受診控えが多数生じたことを背景に,本研究では2019年10月~2020年3月と2020年4月以降に実施した歯周病検査値から,プロービング深さ(PD),プロービング時の出血(BOP)割合(FMBS),プラークコントロールレコード(PCR),歯周炎症表面積(PISA),歯周上皮表面積(PESA)を抽出し,予約延期日数との関係を解析した。SPT移行後1年以上継続して来院している対象患者633名中,219名(34.60%)が2020年4月以降の予約を延期した。SPT時のリスクアセスメント(PRA)を参考に,5...
Nutritional factors reflect the periodontal parameters accompanying status. In this study, associations between nutritional factors, blood biochemical items, and clinical were examined in patients with systemic diseases. The study participants 94 heart disease, dyslipidemia, kidney or diabetes mellitus. Weak negative correlation coefficients found nine ten factors. Stage, grade, mean probing depth (PD), rate of PD 4−5 mm, ≥ 6 attachment level (CAL), bleeding on (BOP) weakly correlated...
Enamel matrix derivative (EMD) has demonstrated beneficial effects on wound healing following surgery. However, the of recombinant human fibroblast growth factor 2 (rhFGF-2) in periodontal regeneration therapy have not been extensively studied. This retrospective study was conducted to compare outcomes modified papilla preservation technique (mPPT) between EMD and rhFGF-2 therapies.
This study investigated the relationship between number of days that hospital visits were postponed and changes in clinical parameters due to spread coronavirus disease 2019 (COVID-19), after Japanese government declared a state emergency April 2020.
Periodontitis is a chronic inflammatory disease which causes tooth mobility and loss due to alveolar bone resorption.Exosomes are extracellular vesicles secreted by cells that contain microRNAs (miRNAs) proteins thought be involved in host cell function cellcell communication.In this study, osteoblastlike Saos2 were stimulated tumor necrosis factor α (TNF-α) or interleukin 1β (IL -1β) investigate the expressions of exosome miRNAs state.Relative amounts exosomes with without stimulation TNF-α...