A5055333415- Diabetes Treatment and Management
- Metabolism, Diabetes, and Cancer
- Diabetes Management and Research
- Chronic Disease Management Strategies
- Diabetes Management and Education
- Vaccine Coverage and Hesitancy
- Pharmaceutical Practices and Patient Outcomes
- Pharmacology and Obesity Treatment
- Pharmaceutical studies and practices
- Health Systems, Economic Evaluations, Quality of Life
- Bone health and osteoporosis research
- Gastric Cancer Management and Outcomes
- Chronic Lymphocytic Leukemia Research
- Influenza Virus Research Studies
- Health, Medicine and Society
- Pharmaceutical industry and healthcare
- Bone health and treatments
- Hip and Femur Fractures
- Patient Satisfaction in Healthcare
- Neuroendocrine Tumor Research Advances
- Oral and gingival health research
- Obesity and Health Practices
- Inhalation and Respiratory Drug Delivery
- Erythropoietin and Anemia Treatment
- Gout, Hyperuricemia, Uric Acid
Stavros Niarchos Foundation
2022
University of Leicester
2019-2022
Université Paris Cité
2014-2019
Sorbonne Université
2011-2019
Ibero American University
2019
Roche (France)
2018-2019
Azienda Ospedaliera San Gerardo
2015-2019
Société Française de Médecine d'Urgence
2005-2018
Inserm
2015
Szent Imre Egyetemi Oktatókórház
2015
Inhaled insulin (INH, Exubera) is under investigation for preprandial treatment of patients with type 1 and 2 diabetes (1–3). This dry-powder formulation delivered by aerosol, permitting the noninvasive administration rapid-acting (4). Preliminary studies have shown that INH provides reproducible effective control glycemia (1,5–7). randomized controlled trial examined extent to which availability affects perceived acceptability therapy among who failed achieve target on current...
The aim of this study was to investigate whether the efficacy liraglutide observed in randomized controlled trials translates into therapeutic benefits French population during routine clinical practice. This observational, prospective, multicenter included 3152 adults with type 2 diabetes who had recently started or were about start treatment. During years follow-up, an evaluation reasons for prescribing liraglutide, maintenance dose changes combined antidiabetic treatments, level glycemic...
Abstract Background Although insulin therapy is well-accepted by symptomatic diabetic patients, it still often delayed in less severe whom injectable remains under-used. A better understanding of patients' perception would eventually help physicians to adopt the most appropriate dialogue when having motivate patients initiate or intensify injection. Methods The 'Studying Hurdles Insulin Prescription' (SHIP) questionnaire was developed based on a list concepts derived from three focus groups,...
What is known and Objective Prescribing represents an important medical action especially in primary care. However, irrational prescribing common has impact on clinical economic outcomes. Therefore, there a growing need to rationalize prescribing. Knowledge of influential factors crucial for achieving this. The aim the present study was identify behavioural, normative control beliefs GPs regarding Greece. Methods Focus group sessions were conducted three geographically defined areas working...
Irrational prescribing of over-the-counter (OTC) medicines in general practice is common Southern Europe. Recent findings from a research project funded by the European Commission (FP7), "OTC SOCIOMED", conducted seven countries, indicate that physicians countries Mediterranean Europe region prescribe to higher degree comparison other participating countries. In light these findings, feasibility study has been designed explore acceptance pilot educational intervention targeting various...
The present study aimed to compare the projected long-term clinical and cost implications associated with liraglutide, sitagliptin glimepiride in patients type 2 diabetes mellitus failing achieve glycemic control on metformin monotherapy France.Clinical input data for modeling analysis were taken from two randomized, controlled trials (LIRA-DPP4 LEAD-2). Long-term (patient lifetime) projections of outcomes direct costs (2013 Euros; €) made using a validated computer simulation model...
SUMMARY: Prospective Observational Scientific Study Investigating Bone Loss Experience in Europe (POSSIBLE EU®) is an ongoing longitudinal cohort study that utilises physician- and patient-reported measures to describe the characteristics management of postmenopausal women on bone loss therapies. We report design baseline 3,402 recruited from general practice across five European countries. PURPOSE: The POSSIBLE EU® a describing receiving medications. METHODS: Between 2005 2008,...
What is known and objective Polypharmacy has a significant impact on patients' health with overall expenditure over-the-counter (OTC) medicines representing substantial burden in terms of cost treatment. The aim this study, which was conducted within the framework European Project funded by Union under Seventh Framework Programme entitled OTC-SOCIOMED, to report possible determinants patient behaviour regarding consumption medicines, particularly OTCs, context primary care. Methods A...
Objectifs : La vaccination est efficace pour réduire morbidité et mortalité liées aux maladies infectieuses. Les médecins généralistes sont le premier effecteur de la en France. Notre objectif était mener une étude exploratoire qualitative chez les afin caractériser facteurs associés à leur engagement dans vaccination. Méthodes Une recherche par entretiens groupe suivant un guide discussion semi-directif a été réalisée. Trente-six diverses régions françaises ont participé six groupe. analyse...
The objective of this subgroup analysis is to investigate the effectiveness liraglutide in people with type 2 diabetes (T2D) treated within primary care physician (PCP) and specialist settings. EVIDENCE a prospective, observational study 3152 adults T2D recently starting or about start treatment France. We followed patients PCP settings for years evaluate glycemic control body weight reduction. Furthermore, we evaluated changes combined antihyperglycemic treatments, reasons prescribing...
Abstract Aim To examine the impact of inhaled human insulin (Exubera®, EXU) on patient or physician willingness to adopt after oral glucose‐lowering agent failure. Methods During a randomized controlled trial in primary, secondary and tertiary care Europe North America, 739 patients using ≥ 2 agents with glycated haemoglobin (HbA 1c ) 8.0% were assigned two treatment groups: Group 1 (standard option only). Standard included adjusting therapy (optimizing current regimen adding/omitting...
Primary care physicians (PCPs) play a key role regarding vaccination in France. The aims of the present study were to define scoring rules and assess measurement properties 'Determinants Intentions Vaccinate' (DIVA©) questionnaire that PCPs' attitudes beliefs toward vaccination. DIVA was derived from literature review PCPs focus groups. Scoring early validation determined during cross-sectional conducted During study, had complete for any six vaccine-preventable diseases (VPDs) which they...
À l’heure actuelle, les virus grippaux à l’origine des cas de grippe humaine saisonnière circulant l’échelle mondiale appartiennent deux sous-types A, A(H1N1) et A(H3N2), lignages type B, B/Yamagata B/Victoria. Comme celles dues aux grippes B sont susceptibles d’avoir sévères conséquences qui justifient sa prévention. Jusqu’à présent, en France, vaccins utilisés pour prévenir la étaient trivalents ciblant systématiquement appartenant A l’un ou l’autre B. L’efficacité protectrice est diminuée...
Various aspects of nonadherence to therapy (including medication and lifestyle nonadherence) often appear together. Here we report the association between treatment adherence in gout two character traits patience obedience, which may explain this observation.Data were collected from a cross-sectional study conducted French cohort 1441 adult patients. Patience was assessed using choice receiving €1500 1 year or €500 immediately. Obedience evaluated with single question assessing use seatbelt...
Restes longtemps silencieux, les musees commencent timidement a prendre en compte l’importance du son dans une approche museographique contemporaine. Paradoxalement, expositions consacrees la musique sont plus difficiles apprehender, le devenant lui-meme objet et sujet de presentation. Les solutions ne pas seulement techniques; un veritable travail conception sonore est envisager des phase definition, recherche d’une coherence d’un parti pris applique l’ensemble parcours. Cette collaboration...
Objective: The purpose of the trial was to examine impact inhaled human insulin (INH) on patient or physician willingness adopt after oral diabetes agent failure. Research design and methods: EXPERIENCE a one-year randomized controlled conducted at primary, secondary tertiary care facilities in Europe North America. primary study endpoint difference glycated hemoglobin (A 1c ) between groups 26 weeks, results from that phase have been reported previously. present report concerns second...