Xiaoyun Zhang

ORCID: 0000-0002-8994-1012
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About
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Research Areas
  • Automotive and Human Injury Biomechanics
  • Transportation Safety and Impact Analysis
  • Prenatal Screening and Diagnostics
  • Reproductive Biology and Fertility
  • Simulation and Modeling Applications
  • Vehicle Dynamics and Control Systems
  • Industrial Technology and Control Systems
  • Traffic and Road Safety
  • Advanced Algorithms and Applications
  • Reproductive System and Pregnancy
  • Spectroscopy and Chemometric Analyses
  • Video Coding and Compression Technologies
  • Traditional Chinese Medicine Analysis
  • Simulation Techniques and Applications
  • Traffic control and management
  • Welding Techniques and Residual Stresses
  • Computational Drug Discovery Methods
  • Seismic Performance and Analysis
  • Mechanical stress and fatigue analysis
  • Vibration Control and Rheological Fluids
  • Lung Cancer Treatments and Mutations
  • Vibration and Dynamic Analysis
  • Autonomous Vehicle Technology and Safety
  • BIM and Construction Integration
  • Advanced Sensor and Control Systems

Sichuan University
2016-2025

West China Hospital of Sichuan University
2025

Guangxi University
2025

Guangxi University of Chinese Medicine
2025

McGill University
2009-2025

Jining Medical University
2025

Microsoft (Norway)
2025

Shanghai Jiao Tong University
2012-2024

Wannan Medical College
2023-2024

McGill University Health Centre
2010-2024

Progression to severe disease is a difficult problem in treating coronavirus 2019 (COVID-19). The purpose of this study explore changes markers COVID-19 patients. Sixty-nine patients were included. Patients with showed significant lymphocytopenia. Elevated level lactate dehydrogenase (LDH), C-reactive protein (CRP), ferritin, and D-dimer was found most cases. Baseline interleukin-6 (IL-6) be associated severity. Indeed, the increase baseline IL-6 positively correlated maximal body...

10.15252/emmm.202012421 article EN cc-by EMBO Molecular Medicine 2020-05-19
Patryk Skowron Hamza Farooq Florence M.G. Cavalli A. Sorana Morrissy Michelle Ly and 94 more Liam D. Hendrikse Evan Y. Wang Haig Djambazian Helen Zhu Karen Mungall Quang M. Trinh Tina Zheng Shizhong Dai Ana Guerreiro Stücklin Maria C. Vladoiu Vernon Fong Borja Holgado Carolina Nör Xiaochong Wu Diala Abd-Rabbo Pierre Bérubé Yu Chang Wang Betty Luu Raúl A. Suárez Avesta Rastan Aaron H. Gillmor John J. Y. Lee Xiaoyun Zhang Craig Daniels Peter B. Dirks David Malkin Éric Bouffet Uri Tabori James Loukides François Doz Franck Bourdeaut Olivier Delattre Julien Masliah‐Planchon Olivier Ayrault Seung-Ki Kim David Meyronet Wiesława Grajkowska Carlos Gilberto Carlotti Carmen de Torres Jaume Mora Charles G. Eberhart Erwin G. Van Meir Toshihiro Kumabe Pim J. French Johan M. Kros Nada Jabado Bolesław Lach Ian F. Pollack Ronald L. Hamilton Amulya A. Nageswara Rao Caterina Giannini James M. Olson László Bognár Álmos Klekner Karel Zitterbart Joanna J. Phillips Reid C. Thompson Michael K. Cooper Joshua B. Rubin Linda M. Liau Miklós Garami Péter Hauser Kay Ka Wai Li Ho‐Keung Ng Wai Sang Poon G. Yancey Gillespie Jennifer A. Chan Shin Jung Roger E. McLendon Eric M. Thompson David Zagzag Rajeev Vibhakar Young Seob Shin Maria Luisa Garrè Ulrich Schüller Tomoko Shofuda Cláudia C. Faria Enrique López‐Aguilar Gelareh Zadeh Chi‐chung Hui Vijay Ramaswamy Swneke D. Bailey Steven J.M. Jones Andrew J. Mungall Richard A. Moore John A. Calarco Lincoln Stein Gary D. Bader Jüri Reimand Jiannis Ragoussis William A. Weiss Marco A. Marra Hiromichi Suzuki Michael D. Taylor

Abstract Sonic hedgehog medulloblastoma encompasses a clinically and molecularly diverse group of cancers the developing central nervous system. Here, we use unbiased sequencing transcriptome across large cohort 250 tumors to reveal differences among molecular subtypes disease, demonstrate previously unappreciated importance non-coding RNA transcripts. We identify alterations within cAMP dependent pathway ( GNAS , PRKAR1A ) which converge on GLI2 activity show that 18% have genetic event...

10.1038/s41467-021-21883-0 article EN cc-by Nature Communications 2021-03-19

Abstract Background Nurses play an important role in healthcare development. The increasing demands for nurses mean that nursing schools at the undergraduate level have responsibility to ensure patient safety and quality care through a well-designed curriculum. This research aimed evaluate effect of teaching method combined with situational awareness case-based seminars comprehensive skills practice course on self-directed learning, professional identity, academic self-efficacy, theoretical...

10.1186/s12909-024-05104-y article EN cc-by BMC Medical Education 2024-02-06

Background: Postmenopausal Osteoporosis (PMOP) is characterized by decreased bone mass and deterioration of microarchitecture, leading to increased fracture risk. Current treatments often have adverse effects, necessitating safer alternatives. Kaempferol, a flavonoid identified as key active component the traditional Chinese medicine Yishen Gushu formula, has shown promise in improving health, but its mechanisms PMOP treatment remain unclear. Objective: The aim this study was investigate...

10.2174/0113862073354862241205062019 article EN Combinatorial Chemistry & High Throughput Screening 2025-01-16

Background: The outbreak of coronavirus disease 2019 (COVID-19) in Wuhan City, China spreads rapidly since December, 2019. Most patients show mild symptoms, but some them develop into severe disease. There is currently no specific medication. purpose this study to explore changes markers peripheral blood COVID-19 patients, which may be value monitoring. Methods: Clinical data with nonsevere and type diagnosed by laboratory test our institution were collected. relationship between cells...

10.2139/ssrn.3548761 article EN SSRN Electronic Journal 2020-01-01

AimsEndothelial progenitor cells (EPCs) play a pivotal role in endothelial repair after artery injury. The chemokine receptor CXCR4 is key modulator of the homing EPCs to impaired and reendothelialization. In this study, we addressed hypothesis that gene transfer could enhance reendothelialization capacity EPCs.

10.1093/cvr/cvq207 article EN Cardiovascular Research 2010-06-23

Oral leukoplakia (OLK) is a potentially malignant disorder of the oral cavity. However, underlying mechanism OLK still unclear. In this study, we explore possible miRNAs involved in OLK.Using miRNA microarrays, profiled expression and malignantly transformed (mtOLK) tissue samples. The upregulation miR-31*, miR-142-5p, miR-33a, miR-1259, miR-146b-5p, miR-886-3p, miR-886-5p, miR-519d, miR-301a along with downregulation miR-572, miR-611, miR-602, miR-675, miR-585, miR-623, miR-637, miR-1184...

10.1371/journal.pone.0038648 article EN cc-by PLoS ONE 2012-06-18

STUDY QUESTIONCan vaginoplasty in patients with Mayer–Rokitansky–Küster–Hauser syndrome (MRKHS) be achieved using an acellular porcine small intestinal submucosa (SIS) graft?

10.1093/humrep/deu341 article EN Human Reproduction 2015-01-16

While there is a consensus on the expanding importance of China–Africa economic relationship, much more debate how to portray relationship. Thus, this study aimed examine impacts trade and Chinese foreign direct investment (FDI) growth African countries controlling mediating role institutional quality. The two-step system Generalized method moments (GMM) model applied using robust data for period 2003–2017. Drawing complementary theoretical perspectives, took into account conditional effect...

10.3390/economies8030053 article EN cc-by Economies 2020-06-29

Can surgical reconstruction of the cervix and vagina in patients be achieved using an acellular porcine small intestinal submucosa (SIS) graft? Our experiences combined laparoscopic vaginal cervicovaginal SIS graft eight were positive, with successful no complications, cervical stenosis or stenosis. In agenesis dysgenesis uterine vagina, internal genitalia is a challenging problem for gynecologists. Hysterectomy creation artificial was treatment choice 1990s. Recently, conservative...

10.1093/humrep/det470 article EN Human Reproduction 2014-01-28

This study aimed to assess the epidemiological features and explore potential risk factors for early neurological deterioration (END) in patients with acute single small subcortical infarction (SSSI) who underwent antiplatelet therapy without carotid artery stenosis.Patients SSSI, as confirmed by cranial magnetic resonance imaging (MRI), were hospitalized within 48 h after onset of symptoms enrolled. END was mainly defined increment National Institutes Health Stroke Scale (NIHSS) score ≥ 2...

10.1186/s12883-023-03128-3 article EN cc-by BMC Neurology 2023-02-27

Chromosomal variations are known to play a role in the etiology of fetal growth restriction (FGR). Here, we intend investigate significance Microarray Analysis (CMA) prenatal diagnosis definite FGR. 182 pregnant women with FGR participated our study, undergoing CMA identify chromosomal abnormalities. The cohort was categorized into isolated FGR, ultrasound soft marker abnormalities, and associated structural malformations. detection rates PCNVs anomalies significantly higher than those group...

10.1186/s12884-025-07305-9 article EN cc-by-nc-nd BMC Pregnancy and Childbirth 2025-02-24

<title>Abstract</title> Integrating spatial transcriptomes and MALDI-MSI is challenge due to no shared coordinates or features. We present \(\:haCCA\), a workflow integrate metabolomes using high-correlated feature pairs modified registration. tested \(\:haCCA\) on pseudo real data, proving that \(\:haCCA\:\)achieving better performance than existing methods. Further application of custom dataset from ICC model enabled both in situ vivo exploration the metabolic alteration effect NETs ICC. A...

10.21203/rs.3.rs-5047159/v1 preprint EN cc-by Research Square (Research Square) 2025-03-27
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