A5025043972- Blood transfusion and management
- Asthma and respiratory diseases
- Blood donation and transfusion practices
- Traumatic Ocular and Foreign Body Injuries
- Cardiac Arrest and Resuscitation
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- COVID-19 and healthcare impacts
- Garlic and Onion Studies
- Inhalation and Respiratory Drug Delivery
- Hemoglobin structure and function
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Respiratory and Cough-Related Research
- Trauma Management and Diagnosis
Charles University
2021-2024
University Hospital Hradec Králové
2021
Importance Red blood cell (RBC) transfusion is common among patients admitted to the intensive care unit (ICU). Despite multiple randomized clinical trials of hemoglobin (Hb) thresholds for transfusion, little known about how these are incorporated into current practice. Objective To evaluate and describe ICU RBC practices worldwide. Design, Setting, Participants International, prospective, cohort study that involved 3643 adult from 233 ICUs in 30 countries on 6 continents March 2019 October...
Abstract Refractory status asthmaticus is the cause of rare cases in-hospital death due to acute bronchial asthma. The most severe unresponsive first, second and next line treatment may be fatal despite aggressive organ support with invasive ventilation extracorporeal membrane oxygenation. Omalizumab, a humanized recombinant monoclonal anti-IgE antibody, an approved add-on biological for However, it not indicated in setting. Here, we report case young patient fully dependent on oxygenation...
Current guidelines discourage prophylactic plasma use in non-bleeding patients. This study assesses global transfusion practices the intensive care unit (ICU) and their alignment with current guidelines.
The authors present the case of a 9-year-old boy who sustained gunshot injury to pericardium by an air gun. penetrative wound was, according performed pre-operative diagnostic methods, initially believed be into cardiophrenic angle left pleural cavity. stabilized patient was indicated for extraction projectile through anterior minithoracotomy, during which found and successfully removed from pericardium. limits assessment, optimal treatment procedures, surgical approaches in pediatric...
Abstract Background: The coronavirus disease (COVID-19) pandemic caused unprecedented research activity all around the world but publications from Central-Eastern European countries remain scarce. Therefore, our aim was to characterise features of in intensive care units (ICUs) among members SepsEast (Central-Eastern Sepsis Forum) initiative. Methods: We conducted a retrospective, international, multicentre study between March 2020-February 2021. All adult patients admitted ICU with...
Abstract The presented case demonstrates the efficacy of omalizumab as a rescue therapy refractory status asthmaticus associated with high IgE levels. Omalizumab should be considered in patients unresponsive to standard treatment.