Christina Whitehead
A5074287339- Intensive Care Unit Cognitive Disorders
- Sepsis Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Cardiac Arrest and Resuscitation
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Acute Kidney Injury Research
- Chronic Kidney Disease and Diabetes
- Dialysis and Renal Disease Management
- Hip and Femur Fractures
- Disaster Response and Management
- Nutrition and Health in Aging
- Traumatic Brain Injury and Neurovascular Disturbances
- Mechanical Circulatory Support Devices
- Adolescent Sexual and Reproductive Health
- Family and Patient Care in Intensive Care Units
- Nosocomial Infections in ICU
- Trauma and Emergency Care Studies
- Blood donation and transfusion practices
- Healthcare Decision-Making and Restraints
- Antibiotics Pharmacokinetics and Efficacy
- Gender Roles and Identity Studies
- Coronary Artery Anomalies
- Frailty in Older Adults
- Muscle and Compartmental Disorders
Nepean Hospital
2021-2025
Manchester University NHS Foundation Trust
2024
Alberta Health Services
2022
University of Alberta
2022
Berry & Associates (United States)
2021
Westmead Hospital
2015-2016
Castle Hill Hospital
2013
Abstract Background There are few reports of new functional impairment following critical illness from COVID-19. We aimed to describe the incidence death or disability, and changes in health-related quality life patients after COVID-19 at 6 months. Methods In a nationally representative, multicenter, prospective cohort study illness, we determined prevalence disability months, primary outcome. measured mortality, return work with World Health Organization Disability Assessment Schedule 2.0...
The outcomes of survivors critical illness due to coronavirus disease (COVID-19) compared with non-COVID-19 are yet be established.
Importance Whether selective decontamination of the digestive tract (SDD) reduces mortality in critically ill patients remains uncertain. Objective To determine whether SDD in-hospital adults. Design, Setting, and Participants A cluster, crossover, randomized clinical trial that recruited 5982 mechanically ventilated adults from 19 intensive care units (ICUs) Australia between April 2018 May 2021 (final follow-up, August 2021). contemporaneous ecological assessment 8599 participating ICUs...
Importance Red blood cell (RBC) transfusion is common among patients admitted to the intensive care unit (ICU). Despite multiple randomized clinical trials of hemoglobin (Hb) thresholds for transfusion, little known about how these are incorporated into current practice. Objective To evaluate and describe ICU RBC practices worldwide. Design, Setting, Participants International, prospective, cohort study that involved 3643 adult from 233 ICUs in 30 countries on 6 continents March 2019 October...
Objective: Trials in critical care have previously used unvalidated systems to classify cause of death. We aimed provide initial validation a method death intensive unit patients. Design, setting and participants: One hundred case scenarios patients who died an ICU were presented online raters, asked select proximate underlying for each, using the Deaths Classifi cation Reason (ICU-DECLARE) system. evaluated two methods categorising (designated Lists A B) one Raters specialists research...
Abstract Background Timing of initiation kidney-replacement therapy (KRT) in critically ill patients remains controversial. The Standard versus Accelerated Initiation Renal-Replacement Therapy Acute Kidney Injury (STARRT-AKI) trial compared two strategies KRT (accelerated standard) with acute kidney injury and found neutral results for 90-day all-cause mortality. Probabilistic exploration the endpoints may enable greater understanding findings. We aimed to perform a reanalysis using Bayesian...
OBJECTIVES: To examine the effect of premorbid β-blocker exposure on mortality and organ dysfunction in sepsis. DESIGN: Retrospective observational study. SETTING: ICUs Australia, Czech Republic, United States. PATIENTS: Total 4,086 critical care patients above 18 years old with sepsis between January 2014 December 2018. INTERVENTION: Premorbid beta-blocker exposure. MEASUREMENTS AND MAIN RESULTS: One thousand five hundred fifty-six (38%) were identified. Overall ICU rate was 15.1%. In...
Recombinant erythropoietin (EPO) administered for traumatic brain injury (TBI) may increase short-term survival, but the long-term effect is unknown. We conducted a pre-planned follow-up of patients in multicentre TBI trial (2010–2015). invited survivors to and evaluated survival functional outcome with Glasgow Outcome Scale-Extended (GOSE) (categories 5–8 = good outcome), secondly, determined relative baseline function (sliding scale). used analysis assess time death absolute risk...
Sepsis is associated with a dysregulated inflammatory response to infection. Despite the activation of inflammation, an immune suppression often observed, predisposing patients secondary infections. Therapies directed at restoration immunity may be considered but should guided by status patients. In this paper, we described use high-dimensional flow cytometry (HDCyto) panel assess immunophenotype sepsis. We then isolated peripheral blood mononuclear cells (PBMCs) from septic shock and...
Background: Australian men are likelier to die younger than women, often from preventable diseases or conditions. Gendered health promotion has improved men’s engagement with services, nurses playing a central role in information and healthcare design. The primary aim of this research was survey senior clinical executive on their understanding perception health. Methods: A cross-sectional quantitative online attended by within single hospital setting metropolitan Sydney between June 2022...
Abstract Thesis Statement Men experience poorer health outcomes than females and gender specific targeted promotion needs to adequately address this bias. Methodology This prospective observational study audited all printed promotional materials in facility waiting rooms within a defined geographic region. A total of 24 sites were surveyed which included general practice centres, community centres hospitals. The literature posters, brochures, booklets. Results There 1143 across the sites. Of...
Issue addressed Currently, in Australia, male health outcomes are poorer than that of females, with males experiencing a lower life expectancy, accounting for 62% the premature deaths. Exploring male-specific promotional material facility waiting rooms provides an opportunity to examine available information. There few studies on health-related education patients, families and carers general practitioner (GP) rooms, no content rooms. Methods This prospective observational study audited all...
To evaluate the feasibility of conducting a prospective randomised controlled trial (pRCT) comparing remifentanil and fentanyl as adjuncts to sedate mechanically ventilated patients. Single-center, open-labelled, pRCT with blinded analysis. Australian tertiary intensive care unit (ICU). Consecutive adults between June 2020 August 2021 expected receive invasive ventilation beyond next day requiring opioid infusion were included. Exclusion criteria pregnant/lactating women, intubation >12 h,...
Background: Home Telemonitoring (HTM) may reduce heart failure (HF) hospitalizations and mortality by improving patient knowledge compliance, increasing prescription of guideline-based medication or earlier intervention. HTM symptoms, rate blood pressure (BP) should facilitate titration neurohormonal antagonists diuretics. Aims: To assess, in a "real-world" setting, the impact compared to usual care on HF medication, comparing numbers patients reaching >50% >100% target doses medication....
<h3></h3> The FMLM Trainee Steering Group (TSG) sought to capture the lessons learnt through a series of interviews and blogs from individuals stepping forward into leadership challenges during COVID19 Pandemic. This included clinicians Interim Foundation doctors chief executives give wide view leadership-in-action understand what have been so far those individuals. opportunity enabled take stock reflect on their own behaviours team/organisation was documented blogs. Each roles interviewed...