The incredible potential for fluorescent proteins to revolutionize biology has inspired the development of a variety design strategies address an equally broad range photophysical characteristics, depending on applications. Of these, that simultaneously exhibit high quantum yield, red-shifted emission, and wide separation between excitation emission wavelengths (Large Stokes Shift, LSS) are rare. pursuit LSS systems led formation complex, obtained from marriage rationally engineered protein...

Abstract Transparent luminescent solar concentrators (TLSCs) selectively harvest ultraviolet and near‐infrared photons. Due to the absence of electrodes, busbars, collection grids over harvesting area, device structure enables these devices achieve highest levels transparency aesthetics. Recently, CO i 8DFIC has been developed as a nonfullerene acceptor in organic photovoltaics with unprecedented performance. In this work, acceptors are introduced into TLSCs luminophores. The impact...

Abstract Visibly transparent luminescent solar concentrators (TLSC) can optimize both power production and visible transparency by selectively harvesting the invisible portion of spectrum. Since primary applications TLSCs include building envelopes, greenhouses, automobiles, signage, mobile electronics, maintaining aesthetics functionalities is as important achieving high conversion efficiencies (PCEs) in practical deployment. In this work, massive‐downshifting phosphorescent nanoclusters...

Visibly transparent luminescent solar concentrators (TLSC) have the potential to turn existing infrastructures into net-zero-energy buildings. However, reabsorption loss currently limits device performance and scalability. This is typically defined by Stokes shift between absorption emission spectra of luminophores. In this work, shifts (SS) near-infrared selective-harvesting cyanines are altered substitution central methine carbon with dialkylamines. We demonstrate varying SS values over 80...

Abstract Molecular reactivity can change dramatically with the absorption of a photon due to difference electronic configurations between excited and ground states. Here we report on discovery modular system (Schiff base formed from an aldehyde amine) that upon photoexcitation yields more basic imine capable intermolecular proton transfer protic solvents. Ultrafast dynamics state conjugated Schiff reveals pathway for transfer, culminating in 14‐unit increase p K give * >20 ethanol.

An efficiently siRNA transporting nanocarrier still remains to be developed. In this study, utilizing the dual stimulus of acid tumor extracellular environment and redox effect glutathione in cytosol, a new system combining triple effects folate targeting, sensitive polymer micelles, bio-reducible disulfide bond linked siRNA-cell penetrating peptides (CPPs) conjugate is developed suppress c-myc gene expression breast cancer (MCF-7 cells) both vitro vivo. Subsequent research demonstrates that...

FR-1V, a fluorene-based aldehydic chromophore, binds its target protein as an imine to yield highly bathochromic pigment, CF-2, prototypic protein-dye tagging system whose NIR emission can be spatiotemporally switched ON by rapid UV-light activation. This is achieved through photoisomerization of the and subsequent protonation. We demonstrate no-wash protocol for live cell imaging subcellular compartments in variety mammalian lines with minimal fluorescence background.

Utilizing two robust C–C bond-forming reactions, the Baylis–Hillman reaction and Diels–Alder reaction, we report a highly enantio-, regio-, diastereoselective synthesis of hexahydro-2H-chromenes via sequential [4 + 2] cycloadditions. These tandem formal cycloadditions have also been performed as "one-pot" sequence to access corresponding heterocycles constituting up five contiguous stereocenters in excellent yields stereoselectivity.

Human cellular retinol binding protein II (hCRBPII) was used as a engineering platform to rationally regulate absorptive and emissive properties of covalently bound fluorogenic dye. We demonstrate the thio-dapoxyl analog via formation protonated imine between an active site lysine residue chromophore's aldehyde. Rational manipulation electrostatics pocket results in 204 nm shift absorption 131 emission. The is readily expressed mammalian systems binds with exogenously delivered fluorophore...

Abstract A reengineered human cellular retinol binding protein II (hCRBPII), a 15‐kDa belonging to the intracellular lipid (iLBP) family, generates highly fluorescent red pigment through covalent linkage of merocyanine aldehyde an active site lysine residue. The complex exhibits “turn‐on” fluorescence, due weakly that “lights up” with subsequent formation strongly dye within pocket protein. Cellular penetration is rapid, and fluorophore maturation nearly instantaneous. hCRBPII/merocyanine...

Abstract Molecular reactivity can change dramatically with the absorption of a photon due to difference electronic configurations between excited and ground states. Here we report on discovery modular system (Schiff base formed from an aldehyde amine) that upon photoexcitation yields more basic imine capable intermolecular proton transfer protic solvents. Ultrafast dynamics state conjugated Schiff reveals pathway for transfer, culminating in 14‐unit increase p K give * >20 ethanol.

The absolute stereochemistry of chiral carboxylic acids is determined as a di(1-naphthyl)methanol ester derivative. Computational scoring conformations favoring either P or M helicity the naphthyl groups, capable exciton-coupled circular dichroic coupling, leads to predicted for derivatized acids.

Visibly transparent luminescent solar concentrators (TLSCs) can optimize both power production and visible transparency by selectively harvesting the invisible portion of spectrum. Since primary applications TLSCs include building envelopes, greenhouses, automobiles, signage, mobile electronics, maintaining aesthetics functionalities is as important achieving high conversion efficiencies (PCEs) in practical deployment. In this work, we combine massive-downshifting phosphorescent nanoclusters...

An engineered hCRBPII protein binds a coumarin-based fluorophore to yield photoswitchable system via Michael/retro-Michael addition of cysteine residue. Alternate UV/visible light irradiation accesses the two optical states.

ZnS nanoparticles have been prepared by using 2, 3-dimercaptoethylthiopropanethiol (BES) as the coordinating modifier reagent to form Zn-thiol complex at low reaction temperatures. By controlling experimental conditions, diameter of nanopaticles can be tuned from 43 nm 115 nm. Systematic experiments were carried out investigate factors such amounts reagents (thiourea and BES) temperature, which great influence on sizes products. And when content BES is much higher, with mercapto surface...

A binary and ternary rare earth complexes were synthesized. The structure composition of the characterized by FT-IR Elemental Analyzer. It is found that have excellent fluorescence intensity thermal stability. Photoluminescent measurements show Phenanthroline (Phen) could efficiently transfer energy to Eu 3+ sensitize luminescence . copolymers complexes, methyl methacrylate (MMA) methacrylic acid (HMA) emit characteristic enhanced with content increasing. But apparent Eu(AA) 3 stronger...

Abstract FR‐1V , a fluorene‐based aldehydic chromophore, binds its target protein as an imine to yield highly bathochromic pigment, CF‐2 prototypic protein–dye tagging system whose NIR emission can be spatiotemporally switched ON by rapid UV‐light activation. This is achieved through photoisomerization of the and subsequent protonation. We demonstrate no‐wash protocol for live cell imaging subcellular compartments in variety mammalian lines with minimal fluorescence background.

Visibly transparent luminescent solar concentrators (TLSCs) can optimize both power production and visible transparency by selectively harvesting the invisible portion of spectrum. Since primary applications TLSCs include building envelopes, greenhouses, automobiles, signage, mobile electronics, maintaining aesthetics functionalities is as important achieving high conversion efficiencies (PCEs) in practical deployment. In this work, we combine massive-downshifting phosphorescent nanoclusters...

Wet cleaning is very critical for technology nodes below 40&28nm in ULSI manufacturing. Better clean efficiency and less film damage becomes the main challenge WET processes advanced development. New chemicals were used this article to study BEOL post Etch 40nm node beyond. We compared performance of chemcial A chemical B through CD enlargement, kink profile, Cu loss, inline defect WAT. Experimental results indicated that copper loss better than B, even though defect, enlargement WAT comparable.

The hybrid-photocatalyst was successfully prepared by compositing graphene and TiO 2 in this thesis. properties of the stydited XRD, SEM. hotocatalytic activity evaluated decolorization acid yellow dye solution under visible light irradiation. result shows that main phase is antase . effects different titanium carbon ratio, photocatalysis time, catalyst dosage pH on photocatalytic for are discussed. Under conditions ratio 100:50, time 120 min, dosing concentration 0.1g / L optimum 8,...