A5048706086- Mesoporous Materials and Catalysis
- RNA Interference and Gene Delivery
- Nanoplatforms for cancer theranostics
- Advanced Photocatalysis Techniques
- Advanced biosensing and bioanalysis techniques
- Nanoparticle-Based Drug Delivery
- Metal-Organic Frameworks: Synthesis and Applications
- Advanced Nanomaterials in Catalysis
- Catalytic Processes in Materials Science
- Zeolite Catalysis and Synthesis
- Enzyme Catalysis and Immobilization
- Immunotherapy and Immune Responses
- Supercapacitor Materials and Fabrication
- Thermochemical Biomass Conversion Processes
- Advancements in Battery Materials
- Chemical Synthesis and Characterization
- Adsorption and biosorption for pollutant removal
- Catalysis and Hydrodesulfurization Studies
- Pickering emulsions and particle stabilization
- Carbon Nanotubes in Composites
- Bacteriophages and microbial interactions
- Electrocatalysts for Energy Conversion
- Proteins in Food Systems
- Advanced battery technologies research
- Bacterial biofilms and quorum sensing
Yangzhou University
2023-2025
Hunan University of Traditional Chinese Medicine
2025
Education Department of Hunan Province
2025
First Affiliated Hospital of Xi'an Jiaotong University
2025
The University of Queensland
2015-2024
Ministry of Agriculture and Rural Affairs
2021-2024
Henan Agricultural University
2021-2024
Massachusetts Institute of Technology
2024
Nanjing Tech University
2021-2024
Hunan University
2024
Nature's creations with spiky topological features typically exhibit intriguing surface adhesive properties. From micrometer-sized pollen grains that can easily stick to hairy insects for pollination nanoscale virus particles are highly infectious toward host cells, multivalent interactions formed taking advantage of rough surfaces. Herein, this nature-inspired concept is employed develop novel drug delivery nanocarriers antimicrobial applications. A facile new approach developed fabricate...
ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTAnion Assisted Synthesis of Large Pore Hollow Dendritic Mesoporous Organosilica Nanoparticles: Understanding the Composition GradientYannan Yang†, Stefano Bernardi†, Hao Song†, Jun Zhang†, Meihua Yu†, James C. Reid†, Ekaterina Strounina‡, Debra J. Searles†§, and Chengzhong Yu*†View Author Information† Australian Institute for Bioengineering Nanotechnology, The University Queensland, Brisbane, Queensland 4072, Australia‡ Centre Advanced...
ConspectusSilica-based nanoparticles (SNPs) are a classic type of material employed in biomedical applications because their excellent biocompatibility and tailorable physiochemical properties. Typically, SNPs designed as nanocarriers for therapeutics delivery, which can address number intrinsic drawbacks therapeutics, including limited bioavailability, short circulation lifetime, unfavorable biodistribution. To improve the delivery efficiency spatiotemporal precision, tremendous efforts...
Iron oxide nanoparticles (IONPs) have emerging anticancer applications via polarizing tumor-associated macrophages from tumor-promoting phenotype (M2) to tumor-suppressing (M1). However, the underlying mechanism and structure–function relationship remain unclear. We report magnetite IONPs are more effective compared hematite in M1 polarization tumor suppression. Moreover, specifically rely on interferon regulatory factor 5 signaling pathway for down-regulate M2-assoicated arginase-1. This...
Thermal quenching (TQ) has been naturally entangling with luminescence since its discovery, and lattice vibration, which is characterized as multiphonon relaxation (MPR), plays a critical role. Considering that MPR may be suppressed under exterior pressure, we have designed core/shell upconversion (UCL) system of α-NaYF
A new type of monodispersed mesoporous silica nanoparticles with a core–cone structure (MSN‐CC) has been synthesized. The large cone‐shaped pores are formed by lamellae closely packed encircling spherical core, showing similar to the flower dahlia . MSN‐CC pore size 45 nm and high volume 2.59 cm 3 g −1 demonstrates loading capacity proteins successfully delivers active β‐galactosidase into cells, their potential as efficient nanocarriers for cellular delivery molecular weights.
Plasmid DNA molecules with unique loop structures have widespread bioapplications, in many cases relying heavily on delivery vehicles to introduce them into cells and achieve their functions. Herein, we demonstrate that control over delicate nanotopography of silica nanoparticles as plasmid vectors has significant impact the transfection efficacy. For rambutan-, raspberry-, flower-like morphologies composed spike-, hemisphere-, bowl-type subunit nanotopographies, respectively, rambutan-like...
Abstract Novel carbon materials derived from metal‐organic frameworks (MOFs) have attracted much attention, but the commonly inevitable inward contraction during carbonization process has restricted their structural variety and applications. In this work, a novel rigid‐interface induced outward approach is reported for synthesizing hollow mesoporous nanocubes (HMCNCs) by using ZIF‐8 as precursors. HMCNCs exhibit cubic morphology with particle sizes slightly larger than nanocubes. Due to...
Here, a reduction-cation exchange (RCE) strategy is proposed for synthesizing Fe-Co based bimetallic Prussian blue analogs (PBAs) with heterogeneous composition distribution and open cage nanocage architecture. Specially, bivalent cobalt introduced into potassium ferricyanide solution containing hydrochloric acid polyvinyl pyrrolidone. The uniform PBAs opened cages are formed tardily after hydrothermal reaction. Time-dependent evolution characterization on elucidating the RCE mechanism...
Asymmetric mesoporous silica nanoparticles (MSNs) with controllable head-tail structures have been successfully synthesized. The head particle type is tunable (solid or porous), and the tail has dendritic large pores. length coverage on particles are adjustable. Compared to spherical a solid structure (Stöber spheres) large-pore symmetrical MSNs fully covered tails, asymmetrical (HTMSNs) show superior hemocompatibility due reduced membrane deformation of red blood cells decreased level...
Immunosuppressive tumors generally exhibit poor response to immune checkpoint blockade based cancer immunotherapy. Rationally designed hybrid nanoreactors are now presented that have integrated functions as Fenton catalysts and glutathione depletion agents for amplifying the immunogenic cell death activating cells. A simple physical mixture of chemodrugs in combination with blockades show synergistically concurrently enhanced chemo-immunotherapy efficacy, inhibiting growth both treated...
Mesostructured hollow carbon nanoparticles have widespread applications. A big challenge in materials science is surfactant-free synthesis of with tunable mesostructures. Herein we report a new sequential heterogeneous nucleation pathway to prepare mesostructured nanoparticles. This strategy relies on two polymerizable systems, i.e., resorcinol formaldehyde and tetraethyl orthosilicate, each which undergoes homogeneous particle growth. By controlling the polymerization kinetics systems when...
Abstract The direct depletion of lactate accumulated in the tumor microenvironment holds promise for cancer therapy but remains challenging. Herein, we report a one‐pot synthesis openwork@ dendritic mesoporous silica nanoparticles (ODMSNs) to address this problem. ODMSNs self‐assembled through time‐resolved lamellar growth mechanism feature an openworked core and shell, both constructed by nanosheets ≈3 nm. With large pore size, high surface area volume, exhibited loading capacity (>0.7 g...