The effects of oryzanol and ferulic acid on the glucose metabolism high-fat-fed mice were investigated. Male C57BL/6N randomly divided into 4 groups: NC group fed with normal control diet; HF high-fat (17%) HF-O diet supplemented 0.5% oryzanol; HF-FA acid. All animals allowed free access to experimental diets water for 7 wk. At end period, groups exhibited significantly lower blood level glucose-6-phosphatase (G6pase) phosphoenolpyruvate carboxykinase (PEPCK) activities, higher glycogen...

The comparative effects of oryzanol and ferulic acid on the lipid metabolism antioxidative status high fat-fed mice were investigated. given a diet containing 17% fat (HF), supplemented with (HF-O) or for 7 weeks. control (NC) fed normal diet. HF exhibited increased body weight gain, plasma hepatic total cholesterol triglyceride concentrations, peroxidation rate, reduced high-density lipoprotein level. In general, they also showed lower antioxidant higher lipid-regulating enzymes activities...

Ethanol−water (70:30 v/v) extracts from rice brans removed seeds of two blackish-purple pigmented (Sanhaehyanghyulla and Suwon 415) one nonpigmented (Chuchung) brown cultivars were evaluated for antioxidative, anti-tumor-promoting, anticarcinogenic activities in chemical assays mammalian cells (human leukemia HL-60, marmoset B lymphoblastoid B95-8, Chinese hamster V79 lung cells) by the following tests: inhibition xanthine oxidase activity; chelation ferrous ions; reduction potassium...

Scope We investigated the effects of rice bran and components on tumor growth in mice. Methods results Mice fed standard diets supplemented with bran, γ‐oryzanol, Ricetrienol®, ferulic acid, or phytic acid for 2 weeks were inoculated CT ‐26 colon cancer cells same diet two additional weeks. Tumor mass was significantly lower γ‐oryzanol less so group. inhibition associated following biomarkers: increases cytolytic activity splenic natural killer ( NK ) cells; partial restoration nitric oxide...

We investigated antitumor effects of the following four extracts freeze-dried Hericium erinaceus mushrooms in Balb/c mice intracutaneously transplanted on backs with CT-26 colon cancer cells: HWE, hot water extraction by boiling for 3 h; MWE, microwaving 50% ethanol/water at 60 W min; and ACE AKE, 1% HCl or 3% NaOH 2 h. HWE MWE a higher content β-glucans, determined an assay kit, than MKE were active all bioassays. Gas chromatography/mass spectrometry analyses showed presence 40, 27, 16, 13...

Summary The antioxidative and anti‐allergic activities of fresh aged black garlic extracts were investigated. samples extracted with 70% ethanol (v/v) the total phenolic content was measured. antioxidant capacity assessed by determining scavenging on 1,1‐diphenyl‐2‐picrylhydrazyl hydroxyl radicals, ferricyanide reducing power, ferrous ion‐chelating ability inhibitory effect linoleic acid peroxidation. activity analysed measuring their effects against β‐hexosaminidase release. exhibited...

We investigated the inhibitory effects of black rice (cv. LK1−3−6−12−1−1) bran against 12-O-tetradecanolylphorbol-13-acetate (TPA)-induced skin edema and 2,4-dinitrofluorobenzene (DNFB)-induced allergic contact dermatitis (ACD) in inflammatory mouse models. also determined extract on following biomarkers: pro-inflammatory cytokines tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), interleukin-6 (IL-6), eicosanoids leukotriene B4 (LTB4), prostaglandin E2 (PGE2). Topical application TPA...

A new liquid rice hull smoke extract with a smoky aroma and sugar-like odor prepared by pyrolysis of hulls followed liquefaction the resulting contained 161 compounds characterized GC/MS. Antioxidative, antiallergic, anti-inflammatory activities were assessed in vitro vivo. At pH 5, inhibited 1-diphenyl-2-picrylhydrazyl (DPPH) free radicals suppressed nitric oxide (NO) β-hexosaminidase releases from lipopolysaccharide (LPS)-induced RAW264.7 mouse macrophage leukemia cells ionophore...

The effect of silk protein with different fibroin/sericin compositions on body weight and lipid metabolism in high fat-fed mice was investigated. animals were given experimental diets for 6 weeks: normal control (NC), fat (HF) diet supplemented F100 (pure fibroin, HF-F100), F81 (81:19 fibroin/sericin, w/w, HF-F81) or F50 (50:50 HF-F50). protein-fed showed markedly reduced enhanced profile relative to the HF group. In general, amount fat, triglyceride total plasma cholesterol levels,...

The effects of fermented paste made from soybean, brown rice, or rice in combination with bran red ginseng marc on the glucose metabolism and antioxidative defense system high fat-fed mice were investigated. given experimental diets for eight weeks: Normal control, fat, fat supplemented soybean paste, rice-rice rice-red paste. group showed markedly higher blood level erythrocyte lipid peroxidation than normal control group. Diet supplementation inhibited fat-induced hyperglycemia oxidative...

ABSTRACT: Using a panel of chemical, biochemical, and cell assays, we determined inhibitory effects extracts the pigmented black rice brans on in vitro allergic reactions. Ethanol‐water (70% v/v) from 5 were found to be more effective than an extract nonpigmented cultivar suppressing release histamine β‐hexosaminidase basophilic RBL‐2H3 cells stimulated with both Ionophore A23187 immunoglobulin E (IgE)‐antigen complexes. Suppression was also obtained A23187‐stimulated rat peritoneal mast...

The effect of dietary feeding rice bran and phytic acid on the glucose metabolism in high fat-fed C57BL/6N mice fed was investigated. were given with either a fat diet only (HF group) or supplemented (HF-RB (HF-PA for 7 weeks. control (NC received normal diet. At end experimental period, HF group exhibited substantially higher blood level than NC group. However, HF-RB HF-PA groups showed marked decrease relative to mice. Furthermore, significantly glucokinase (GK) activity lower...

Phytochemicals in some foods are a potential source of bioactive safe compounds for cancer chemoprevention and suppression tumor initiation, promotion, metastasis. In the present study, we evaluated hot water (HWE), microwaved 50% ethanol (MWE), acidic (ACE), alkaline (AKE) extracts fruitbody (sporocarp) Hericium erinaceus (Yamabushitake, Lion's Mane) mushrooms their ability to induce apoptosis (programmed cell death) U937 human monocytic leukemia cells. Cell culture, viability,...

Abstract: A previously characterized rice hull smoke extract (RHSE) was tested for bactericidal activity against Salmonella Typhimurium using the disc‐diffusion method. The minimum inhibitory concentration (MIC) value of RHSE 0.822% (v/v). in vivo antibacterial (1.0%, v/v) also examined a ‐infected Balb/c mouse model. Mice infected with sublethal dose pathogens were administered intraperitoneally 1.0% solution at four 12‐h intervals during 48‐h experimental period. results showed that...

<i>Background/Aims:</i> The purpose of the current study is to investigate influence germinated giant embryonic rice consumption on lipid metabolism and antioxidant system in rats fed a high-cholesterol diet. <i>Methods:</i> Four groups were given diet containing 1 g cholesterol/kg for 5 weeks. control group only received diet, while other 3 experimental each diets made rice, or conventional brown (hereafter referred as GGE-D, GE-D, BR-D, respectively). Plasma hepatic...

This study investigated the protective effect of a liquid rice hull smoke extract (RHSE) against diabetes in alloxan-induced diabetic mice. Antidiabetic effects RHSE were evaluated both rat insulinoma-1 cell line (INS-1) and ICR mice induced by intraperitoneal (ip) injection alloxan. Alloxan treatment (10 mM) increased cellular reactive oxygen species (ROS) levels INS-1 cells, which inversely related to viabilities. inhibited nitric oxide (NO) generation through inhibition inducible synthase...

The comparative effects of doenjang prepared from fermented soybean or brown rice on the body weight and lipid metabolism in C57BL/6N mice fed with high fat diet were investigated. animals randomly divided given experimental diets for eight weeks: normal control diet, supplemented doenjang, rice-rice bran rice-red ginseng marc doenjang. At end period, HF group exhibited a marked increase weight, fat, plasma triglyceride concentration, atherogenic index relative to group. However,...

Fresh ginseng roots were aged in an oven at 80°C for 14 d. The vitro and vivo antioxidant activities of this ginseng, comparison with those the white red ginsengs, evaluated. In assays, ethanolic extracts from showed significantly higher free radical scavenging activity reducing power than ginsengs. mice fed a high fat diet supplemented white, red, or powders. High feeding resulted significant increase lipid peroxidation substantial decrease enzymes animals. However, supplementation powders,...

Endometrial cancer is the sixth most common in women worldwide. Peroxiredoxins (PRDXs) are antioxidant enzymes that serve important roles cell differentiation, proliferation, and apoptosis. In present study, potential associations between PRDX expression endometrial were investigated. The levels of various mRNAs detected by semi-quantitative reverse transcription polymerase chain reaction (RT-PCR) tissues (n=26) normal (n=10). Additionally, isoforms was immunohistochemically examined...