This paper presents a surface plasmon resonance system based on polymer prism chip. The device allows operation in both the angular and wavelength interrogation modes. biochip design is discussed emphasizing effect of ambient temperature over optical behavior. Birefringence effect, polishing, responsivity are also reported. basic mathematical formulation for operating modes discussed, morphological parameters considered data analysis. Experimental sensorgrams obtained at with same chip...

The sensing properties of thin copper (Cu) films near the surface plasmon resonance (SPR), were re-evaluated for metal-air and metal-water interfaces compared with gold (Au) films. For this, we used three different SPR designs, i.e., a prism-based set-up, an optical fiber-based system, grating coupler-based solution. Optimum SPR-excitation conditions are restricted to Cu-metal film thickness 45± 5 nm ATR set-up in aqueous impacts Cu-oxide layer discussed prevented employing Au ultra-thin...

Glyphosate detection and quantification is still a challenge. After an extensive review of the literature, we observed that Fourier transform infrared spectroscopy (FTIR) had practically not yet been used for or quantification. The interaction between zinc oxide (ZnO), silver (Ag2O), Ag-doped ZnO nanocrystals (NCs), as well nanocomposite (Ag-doped ZnO/AgO) glyphosate was analyzed with FTIR to determine whether nanomaterials could be signal enhancers glyphosates. results were further...

Aiming to investigate the graphene usage in optical fiber surface plasmon resonance sensor probes, a theoretical analysis of sensitivity, reflectance, normalized transmitted power, full width at half maximum, and figure merit (FOM) as function sensing region length for different configurations has been developed. Here, some noble metals, such gold (Au), silver (Ag), copper (Cu) have used part region. Considering aqueous solutions analytes, deposition layers over metallic layer improved...

A surface plasmon resonance sensor based on a D-shaped plastic optical fiber using graphene layers coated over thin silver film is numerically analyzed. The performance of the sensing structure studied as function number layers, area length, and polishing depth. Sensor's quality parameters, such signal-to-noise ratio, figure merit, sensitivity, are also calculated. overlay increases sensitivity reaching peak 5,161 nm/RIU for 16 layers. sensor's parameters length decrease. On other hand,...

Surface plasmon resonance (SPR) sensors, utilizing thin aluminum (Al) films, are reported. The sensor designs based in the novel optical trapezoidal prism chip, made from either polymer or BK7 glass. Optimum Al-film thickness was determined to 20 ± 5 nm, and deposited by thermal e-beam evaporation rf-magnetron sputtering. Upon contact air, de-ionized aqueous solution, a self-limited surface oxide layer forms. Determined ellipsometric recordings, its grows 4.6 0.6 nm air 12.3 2 wet interface....

Surface plasmon resonance sensors are routinely employed optical instruments for biochemical research and suited medical diagnostics. Optical properties associated instrumental performance of nanometer thin sputter deposited Au, Ag Cu films at the metal-water interface reported compared with theoretical predictions. Prominent SP-excitations persist in very metal on BK7 glass substrates film thickness approximately 40-50nm. Thin Au long-term chemically stable neutral aqueous buffer solution....

Thermoelectricity energy harvesting based on the thermoelectric generator (TEG) has had a prominent role in solutions since they have dramatically grown recently due to existence of significant thermal gradients ΔT both natural and industrial environments. However, prove that given environment is adequate generate hard task. In order early evaluate potential get enough be converted electric energy, we propose this paper an automatic emulation system can used with any source simple way....

A prism-based polymeric biochip (called PPBIO), that allows surface plasmon resonance sensing in both angular and spectral or wavelength interrogation modes, was designed constructed. It is formed from high quality polymer materials, which uses injection molding method to the volume manufacture of prisms. Two molds have been manufactured with three four cavities a comparison also presented. Experimental tests were conducted results indicate reduction mechanical stresses birefringence....

Research focused on improving the sensitivity of SPR analytical technology has led to investigation different electric field enhancement elements for incorporation with classic sensor structures. Over past ten years, considerable attention been given ceramic, metal oxide, and 2D materials that not only improve magnitude but are also used as affinity layers improved adsorption molecules. However, focusing improvements these deliver can lead designers explore some themultiple dependencies...

An exchangeable low cost surface plasmon resonance biosensor chip for real-time monitoring of biochemical interactions has been developed. It is based on a simple patented prism design, fabricated from cyclic-olefin co-polymer (COC), which thus allows high throughput fabrication, using injection molding techniques. The sensor can be operated in both, angular and wavelength interrogation modes, ray tracing simulations have investigated the light beams focalization.

A bi-directional linear peristaltic pump is presented that avoids use of a rotating step motor and rollers. Fluid displacement, flow function, respectively, are achieved by means three electro-magnetic actuators. They electronically controlled designed to periodically squeeze an elastic tube contains the liquid. The device reveals very simple construction, maintenance free, has low power consumption, thus accounting for manufacture operation costs. Upon reducing size actuators, it can be...

An optical fiber-based surface plasmon resonance sensor for colorectal cancer diagnosis is presented here. A theoretical analysis performed, where parameters such as length of the sensing region, full width at half maximum, figure merit, and signal-to-noise ratio are investigated three different biochip configurations. Regarding coating, we analyzed silver, gold copper thin films. multimode plastic fiber has been used an substrate, region (i) localized center fiber, (ii) polished a D-shaped...

This article presents an in silico and vitro study concerning the application of a trapezoidal prism-based surface plasmon resonance chip to detect colorectal cancer (CRC) by analyzing mucosa tissue. The sensor is multilayered structure works wavelength interrogation mode (WIM). Performance parameters related metallic film characteristics, such as thickness type metal, were determined. For analyzed noble metals, silver 40 nm has highest sensitivity 6454.12 nm/RIU, 60-nm thick best values for...

The influence of electrothermal feedback and hysteresis on the operation conditions, noise, performance a VO2 transition-edge microbolometer has been evaluated. material undergoes first-order semiconductor-to-metal phase transition (SMT) within temperature range 40<T<70 °C. Due to feedback, all device parameters, including required heat-sink temperature, output voltage current response, response time, linear dynamic range, responsivity, detectivity, display complex nonlinear variations with...

The detection of Leishmania spp. through a disposable surface plasmon resonance (SPR) biochip, using mono- and polychromatic sources, is presented here. A highly specific sensitive-constrained synthetic peptide (LC2) derived from mimotope chagasi antigen was immobilized on the sensing region simple protocol. ELISA- PCR-confirmed negative positive sera infected patients were used. Detection IgG showed fast response with good sensitivity specificity for proposed method.

Introduction: Surface plasmon resonance biosensors are high sensitive analytical instruments that normally employ glass materials at the optical substrate layer. However, use of polymer-based substrates is increasing in last years due to favorable features, like: disposability, ease construction and low-cost design. Review Recently, a SPR biochip was proposed by using monochromatic polychromatic input sources. Its experimental considerations detailed here. Experimental results, aspects from...

A surface plasmon resonance based optical fiber tip sensor using graphene layers coated over a gold thin film is numerically analyzed. The performance of the sensing structure studied as function number and surrounding medium refractive index. Sensor parameters, such sensitivity, full width at half maximum, signal-to-noise ratio, Figure merit are also calculated. overlay increases sensitivity reaching peak 11,402 nmmIU for five index 1.360 RIU. proposed with deposition extra variation.

Most of the fiber optic-based surface plasmon resonance (SPR) sensors use gold or silver metal as part sensing region. It is known from literature that presents a better performance in terms sensitivity, although less stable and strongly affected by oxidation, which turns reduces its lifetime. To overcome this effect, other materials, such gold, are proposed alternatives combined with silver, forming bimetallic layers, leading to higher sensor performance. Furthermore, adding graphene layers...