A5030781312- Ovarian function and disorders
- Lipid metabolism and disorders
- Reproductive Biology and Fertility
- Ovarian cancer diagnosis and treatment
- Cytomegalovirus and herpesvirus research
- Adipose Tissue and Metabolism
- Herpesvirus Infections and Treatments
- Reproductive Health and Technologies
- Cardiovascular Disease and Adiposity
- Liver Disease Diagnosis and Treatment
- Gestational Diabetes Research and Management
- Diet, Metabolism, and Disease
- Hemoglobin structure and function
- Viral gastroenteritis research and epidemiology
- Menstrual Health and Disorders
- Folate and B Vitamins Research
- Animal Virus Infections Studies
- Birth, Development, and Health
- Endometriosis Research and Treatment
- Hair Growth and Disorders
- Reproductive System and Pregnancy
- Nutrition and Health in Aging
- Apelin-related biomedical research
- Escherichia coli research studies
- Blood disorders and treatments
Universidade Federal de Minas Gerais
2015-2025
Hospital das Clínicas da Universidade Federal de Minas Gerais
2016-2023
Rathenau Instituut
2019
Universidade Federal de Sergipe
2015
Centro Universitário de Belo Horizonte
2013
Istituto Nazionale di Fisica Nucleare, Sezione di Lecce
2002
Microbiomas Foundation
1999
Universidad Nacional Autónoma de México
1998
Sapienza University of Rome
1998
Università Cattolica del Sacro Cuore
1994
<ns4:p>Polycystic ovary syndrome (PCOS) is a multifaceted condition characterized by chronic anovulation and excess ovarian activity, in contrast to other causes of that involve dormancy or primary insufficiency. Recent studies indicated PCOS associated with low-grade inflammation women are at increased risk non-alcoholic fatty liver disease. The inflammatory metabolic derangements explained part the coexistence insulin resistance obesity but further fueled androgen excess. New insights into...
To evaluate whether brown adipose tissue (BAT) activity is altered in women with polycystic ovary syndrome (PCOS), and BAT correlates plasma levels of irisin, a myokine that can induce formation.We performed cross-sectional study including PCOS (n = 45) healthy control group 25) matched by age body mass index (BMI).BAT was measured using 18F-FDG positron emission tomography-computed tomography (PET-CT) irisin were validated enzyme immunoassay.Total significantly reduced (maximal standardized...
Polycystic ovary syndrome (PCOS) is a complex disease and the most common endocrine condition that affects women of reproductive age. Its prevalence ranges from 5% to 20%, characterized by hyperandrogenism, menstrual irregularities, presence polycystic dysfunctional ovaries [1] [2] [3] [4] [5] [6].
Polycystic ovary syndrome (PCOS) is a recognized risk factor for nonalcoholic fatty liver disease (NAFLD). The aims of this study were to investigate the prevalence and factors associated with NAFLD in women PCOS evaluate noninvasive indices hepatic fibrosis patients NAFLD.Patients (n = 87) without 40; controls) included. was diagnosed by abdominal ultrasonography after exclusion alcohol consumption viral or autoimmune disease. Anthropometric, clinical metabolic variables, homeostasis model...
Polycystic Ovary Syndrome (PCOS) is associated with a chronic low-grade inflammation and predisposition to hemostatic atherosclerotic complications. This case-control study evaluated the microparticles (MPs) profile in patients PCOS related these MPs clinical biochemical parameters. derived from platelets (PMPs), leuckocytes (LMPs) endothelial cells (EMPs) were evaluated, as well expressing tissue factor (TFMPs), by flow cytometry, comparing women (n = 50) healthy control group 50)....
Abstract Background The high rates of overweight status observed in women with polycystic ovary syndrome ( PCOS ) may reflect dietary intake, and so it is important to investigate diet quality its relationship the obesity among these patients. Methods A cross‐sectional study was conducted which 100 R otterdam criteria) were evaluated considering anthropometric data. evaluation included measurement weight, height, body mass index BMI ), waist circumference WC hip waist–hip ratio. Food intake...
This study aimed to investigate the association between vitamin D (VitD) levels, polymorphisms in VDR gene (ApaI, BsmI, FokI, and TaqI) polycystic ovary syndrome (PCOS) a group of Brazilian women. A total 100 patients with PCOS control women were included. The quantification 25-hydroxyvitamin (25(OH)D) was performed high-performance liquid chromatography (HPLC). Polymorphisms on by PCR-RFLP. BsmI AG genotype more frequent group, while GG (p = .007). frequency Taql CC higher CT most .021)....
It is believed that a dysfunction in adipose tissue plays an important role the pathogenesis of polycystic ovary syndrome (PCOS). Natriuretic peptides are hormones regulate cardiovascular and body fluid homeostasis metabolism. peptide levels reduced individuals with obesity diabetes. This study aimed to investigate whether natriuretic altered women PCOS they correlate adiponectin or insulin sensitivity markers. was cross-sectional at referral center teaching hospital. We evaluated 40...
Abstract Polycystic ovary syndrome (PCOS) is a chronic dysfunction associated with obesity and metabolic disorders that can be ameliorated by treatment metformin. Brown adipose tissue (BAT) has been recently identified in adult humans, irisin myokine induces BAT formation. The aim of this randomized controlled trial was to evaluate whether short term metformin alters activity plasma levels women PCOS. participants were randomly assigned receive (1500 mg/day, n=21) or placebo (n=24) during 60...
Introduction Brazil is a large country, with population of mixed ethnic background and broad variation in dietary physical activity traits across its five main regions. Because data on Brazilian women polycystic ovary syndrome (PCOS) are still scarce, nation-wide collaborative study was designed to determine the prevalence metabolic reproductive abnormalities presence anxiety depression PCOS. In addition, aims at describing how these characteristics distributed PCOS phenotypes detecting...
Polycystic ovary syndrome (PCOS) is the most common endocrine and metabolic disorder that affects women in reproductive age. This study aimed to evaluate Gal-3 levels its role on parameters with PCOS. was measured 44 PCOS 25 recruited as control group for case-control study. were similar between groups (p > 0.05), but showed a positive correlation glucose oral tolerance test (OGTT) (r = 0.403, p 0.037), body mass index (BMI) 0.469, 0.027), insulin 0.453, 0.030) HOMA-IR 0.738, 0.037) group....
Polycystic Ovary Syndrome (PCOS) is a heterogeneous endocrinopathy considered to be the most common metabolic disorder in women of reproductive age. Women with PCOS present an increased risk noncommunicable diseases (NCDs), especially low-grade chronic inflammation mediated by proinflammatory cytokines, and insulin resistance. This study aimed investigate cytokine levels their ratios compared healthy control group. evaluated 97 99 as controls. The diagnosis was performed according...