Silviane A. Miruka

ORCID: 0000-0002-9116-9658
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About
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Research Areas
  • Antimicrobial Resistance in Staphylococcus
  • Genetics, Bioinformatics, and Biomedical Research
  • Microbial Metabolism and Applications
  • Computational Drug Discovery Methods
  • vaccines and immunoinformatics approaches
  • Biomedical and Engineering Education
  • Malaria Research and Control
  • Bacterial Identification and Susceptibility Testing
  • Insect symbiosis and bacterial influences
  • Research Data Management Practices
  • Microbial infections and disease research
  • Bacteriophages and microbial interactions
  • Insect Resistance and Genetics
  • Insect-Plant Interactions and Control

Kenya Medical Research Institute
2024

University of Nairobi
2021

Abstract Drug discovery is an intricate and costly process. Repurposing existing drugs active compounds offers a viable pathway to develop new therapies for various diseases. By leveraging publicly available biomedical information, it possible predict compounds’ activity identify their potential targets across diverse organisms. In this study, we aimed assess the antiplasmodial of from Repurposing, Focused Rescue, Accelerated Medchem (ReFRAME) library using in vitro bioinformatics...

10.1186/s13321-024-00856-7 article EN cc-by Journal of Cheminformatics 2024-05-30

According to the United Nations Educational, Scientific, and Cultural Organization (UNESCO), Open Science is movement make scientific research data accessible all. It has great potential for advancing science. At its core, it includes (but not limited to) open access, data, research. Some of associated advantages are promoting collaboration, sharing reproducibility in research, preventing reinvention wheel, thus saving resources. As becomes more globalized output grows exponentially,...

10.3389/frma.2021.669675 article EN cc-by Frontiers in Research Metrics and Analytics 2021-05-13

<title>Abstract</title> Drug discovery is an intricate and costly process. Repurposing existing drugs active compounds offers a viable pathway to develop new therapies for various diseases. By leveraging publicly available biomedical information, it possible predict compound's activity identify their potential targets across diverse organisms. In this study, we aimed assess the antiplasmodial of from The Repurposing, Focused Rescue, Accelerated Medchem (ReFRAME) library using <italic>in...

10.21203/rs.3.rs-3667644/v1 preprint EN cc-by Research Square (Research Square) 2024-05-13

Staphylococcus aureus cause diseases both in humans and animals. These range from mild to fatal infections thus necessitating development of a specific molecular method for detection pathogenic S. aureus.To identify analyze genetic profile using bacteriophage based biomarkers.Using culture biochemical methods, 148 (87 %) were isolated 170 raw milk samples taken 10 dairy farms Marsabit Isiolo counties Northern Kenya between June 2016 February 2017. The collected directly lactating cows...

10.1002/vms3.676 article EN Veterinary Medicine and Science 2021-12-08

Busseola fusca (Fuller) (Lepidoptera: Noctuidae), the maize stalk borer, is a widespread crop pest in sub-Saharan Africa that has been focus of biological research and intensive management strategies. Here, we present comprehensive annotated transcriptome B. (originally collected Western Province Kenya) based on ten pooled libraries including wide array developmental stages, tissue types, exposures to parasitoid wasps. Parasitoid wasps have used as form biocontrol try reduce losses with...

10.1093/gbe/evaa195 article EN cc-by Genome Biology and Evolution 2020-09-16

According to the United Nations Educational, Scientific, and Cultural Organization (UNESCO), Open Science is movement make scientific research data accessible all. It has great potential for advancing science. At its core, it includes (but not limited to) open access, data, research. Some of associated advantages are promoting collaboration, sharing, reproducibility in research, preventing reinvention wheel, thus saving resources. As becomes more globalized output grows exponentially,...

10.31730/osf.io/mgkw3 preprint EN 2021-02-18
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