A5032047966- SARS-CoV-2 and COVID-19 Research
- COVID-19 epidemiological studies
- Viral Infections and Outbreaks Research
- SARS-CoV-2 detection and testing
- Bacteriophages and microbial interactions
- Biomedical and Engineering Education
- Biosensors and Analytical Detection
- Heparin-Induced Thrombocytopenia and Thrombosis
- Genetics, Bioinformatics, and Biomedical Research
- interferon and immune responses
- Research Data Management Practices
- COVID-19 diagnosis using AI
- Vaccine Coverage and Hesitancy
International Livestock Research Institute
2022-2023
International Centre of Insect Physiology and Ecology
2021
We used whole-genome sequencing of SARS-CoV-2 to identify variants circulating in the Democratic Republic Congo and obtain molecular information useful for diagnosis, improving treatment, general pandemic control strategies.A total 74 isolates were sequenced using Oxford Nanopore platforms. Generated reads processed consensus genome sequences. Sequences with more than 80% coverage variant calling, phylogenetic analysis, classification Pangolin lineage annotation nomenclature.Phylogenetic...
Abstract Vaccination is a key control measure of COVID-19 by preventing severe effects disease outcomes, reducing hospitalization rates and death, increasing immunity. However, vaccination can affect the evolution adaptation SARS-CoV-2, largely through vaccine-induced immune pressure. Here we investigated intrahost recombination single nucleotide variations (iSNVs) on SARS-CoV-2 genome in non-vaccinated vaccinated sequences from Kenyan population to profile viral genetic adaptations driven...
Using classical and genomic epidemiology, we tracked the COVID-19 pandemic in Kenya over 23 months to determine impact of SARS-CoV-2 variants on its progression. surveillance testing data were obtained from Ministry Health, collected daily 306 health facilities. COVID-19-associated fatality also these facilities communities. Whole genome sequencing carried out 1241 specimens. Over duration (March 2020–January 2022), experienced five waves characterized by attack rates (AR) between 65.4 137.6...
According to the United Nations Educational, Scientific, and Cultural Organization (UNESCO), Open Science is movement make scientific research data accessible all. It has great potential for advancing science. At its core, it includes (but not limited to) open access, data, research. Some of associated advantages are promoting collaboration, sharing reproducibility in research, preventing reinvention wheel, thus saving resources. As becomes more globalized output grows exponentially,...
Using classical and genomic epidemiology, we tracked the COVID-19 pandemic in Kenya over 23 months to determine impact of SARS-CoV-2 variants on its progression.
Abstract Wastewater-based surveillance (WBS) has become a useful public health tool as an early warning system revealing emergence/re-emergence of pathogenic diseases and spread antimicrobial resistance (AMR). WBS is crucial in development rapid response increasing awareness to curb dangers associated with disease emergence antibiotic resistance. In this study, we characterized bacterial pathogens detected wastewater, their composition, relative abundance resistant genes (ARGs) from...