Andrés Alvarado

ORCID: 0000-0002-9125-1221
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About
Contact & Profiles
Research Areas
  • Hydrology and Watershed Management Studies
  • Hydrology and Sediment Transport Processes
  • Water Quality Monitoring and Analysis
  • Hydraulic flow and structures
  • Wastewater Treatment and Nitrogen Removal
  • Groundwater flow and contamination studies
  • Water Systems and Optimization
  • Constructed Wetlands for Wastewater Treatment
  • Flood Risk Assessment and Management
  • Urban Stormwater Management Solutions
  • Wastewater Treatment and Reuse
  • Water Quality and Pollution Assessment
  • Membrane Separation Technologies
  • Aquatic Ecosystems and Phytoplankton Dynamics
  • Algal biology and biofuel production
  • Water resources management and optimization
  • Multimodal Machine Learning Applications
  • Soil and Water Nutrient Dynamics
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Water Quality Monitoring Technologies
  • Advanced Neural Network Applications
  • Diatoms and Algae Research
  • Face recognition and analysis
  • Visual Attention and Saliency Detection
  • Water-Energy-Food Nexus Studies

University of Cuenca
2013-2024

Fundación Universitaria Internacional del Tropico Américano
2017

Ghent University
2011-2013

Adoptive cell therapies (ACT) have shown reduced efficacy against solid tumor malignancies compared to hematologic malignancies, partly due the immunosuppressive nature of microenvironment (TME). ACT may be enhanced with pleiotropic cytokines that remodel TME; however, their expression needs tightly controlled avoid systemic toxicities. Here we show T cells can armored membrane-bound surface regulated using drug-responsive domains (DRDs) developed from 260-amino acid protein human carbonic...

10.1038/s42003-024-07410-z article EN cc-by-nc-nd Communications Biology 2025-01-09

Abstract Background: TIL cell therapy can induce durable disease regression in solid tumors. engineered with regulatable mbIL15 (cytoTIL15TM cells) demonstrate interleukin 2-independent expansion and function (Burga SITC 2023) lead to clinical responses (Amaria ASCO 2024). Furthermore, co-regulated expression of LIGHT show enhanced efficacy fibroblast-containing, immunologically cold tumors (Koscso AACR Chondrosarcomas are often mesenchymal stem-cell origin similar transcriptional signature...

10.1158/2326-6074.io2025-b001 article EN Cancer Immunology Research 2025-02-23

Industrial development has made new products available to people make their lives easier. Items such as food, cleaning, personal care and health products, among others, are processed, sold consumed daily by all age groups. These include in formulation inorganic organic chemicals with the purpose of improving or increasing some properties, making them more attractive consumer. substances strictly controlled during production so that final product may be safely consumed. In most cases,...

10.4136/ambi-agua.2436 article EN cc-by Ambiente e Agua - An Interdisciplinary Journal of Applied Science 2019-11-11

Sludge management in waste stabilization ponds (WSPs) is essential for safeguarding the system performance. accumulation patterns WSPs are strongly influenced by pond hydrodynamics. CFD modeling was applied to study relation between velocity profiles and sludge deposition during 10 years of operation Ucubamba WSP Cuenca (Ecuador). One tracer experiment performed three scenarios based on bathymetric surveys were simulated. A residence time distribution (RTD) analysis illustrated decrease...

10.2166/wst.2012.450 article EN Water Science & Technology 2012-10-04

Abstract The behavior of many physical systems is described by means differential equations. These equations are usually derived from balance principles and certain modelling assumptions. For realistic situations, the solution associated initial boundary value problems requires use some discretization technique, such as finite differences or volumes. This research tackles numerical a 1D equation to predict water surface profiles in river, well estimate so-called roughness parameter. A very...

10.1186/s40323-022-00226-8 article EN cc-by Advanced Modeling and Simulation in Engineering Sciences 2022-06-30

Dissolved oxygen is an essential controlling factor in the performance of facultative and maturation ponds since both take many advantages algal photosynthetic oxygenation. The rate this photosynthesis strongly depends on time during day location a pond system, whose roles have been overlooked previous guidelines operation maintenance (O&M). To elucidate these influences, linear mixed effect model (LMM) was built data collected from three intensive sampling campaigns waste stabilization...

10.3390/w10020201 article EN Water 2018-02-13

The problem of machine learning systems demonstrating bias towards specific groups individuals has been studied extensively, particularly in the Facial Recognition area, but much less so Automatic Speech (ASR). This paper presents initial results on "Casual Conversations" – a publicly released 846 hour corpus designed to help researchers evaluate their computer vision and audio models for accuracy across diverse set metadata, including age, gender, skin tone. entire manually transcribed,...

10.1109/icassp43922.2022.9747501 article EN ICASSP 2022 - 2022 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP) 2022-04-27

The overall performance of a wastewater treatment plant is in addition to the effectiveness biokinetic processes controlled by flow dynamics. A wide used technique characterize water dynamics use tracers. At full-scale tracer experiments plants provide insufficient information completely grasp Additionally results are often biased uncontrolled external factors. As alternative, computational fluid dynamic (CFD) models for analysis existing and design new have been increasingly over last...

10.18537/mskn.02.01.05 article EN cc-by MASKANA 2011-06-25

Studies on limnology are essential to reservoir management; nevertheless, few known about the limnological features of Andean reservoirs in Ecuador. To overcome this limitation information, from December 2018 2019, characteristics El Labrado and Chanlud Machángara river basin (Ecuador south) were examined. Using light/dark bottles technique, primary productivity (PP) phytoplankton was studied conjunction with (1) vertical profiles oxygen concentrations, water temperature, nitrogen,...

10.3390/w16142012 article EN Water 2024-07-16

Object understanding in egocentric visual data is arguably a fundamental research topic vision. However, existing object datasets are either non-egocentric or have limitations categories, content, and annotation granularities. In this work, we introduce EgoObjects, large-scale dataset for fine-grained understanding. Its Pilot version contains over 9K videos collected by 250 participants from 50+ countries using 4 wearable devices, 650K annotations 368 categories. Unlike prior containing only...

10.1109/iccv51070.2023.01840 article EN 2021 IEEE/CVF International Conference on Computer Vision (ICCV) 2023-10-01

In many medium-sized irrigation systems water is wasted during the night because demand low and supply not reduced accordingly. A hydrodynamic model was applied, using MIKE 11 as a software tool, to simulate abrupt discharge changes their travel times along small canals. Filling emptying of canal were also analyzed. The calibrated with data field experiment that included startup, positive, negative surges. technique developed take into account considerable losses in canal. Performance...

10.1061/(asce)0733-9437(2003)129:2(108) article EN Journal of Irrigation and Drainage Engineering 2003-03-21

Abstract Algal photosynthesis plays a key role in the removal mechanisms of waste stabilization ponds (WSPs), which is indicated variations three parameters, dissolved oxygen, pH, and chlorophyll a. These can be considerably affected by extreme climatic conditions at high altitude. To investigate these effects, sampling campaigns were conducted high-altitude WSP Cuenca (Ecuador). From collected data, first application structure equation modeling (SEM) on pond system was fitted to analyze...

10.2166/wst.2018.254 article EN Water Science & Technology 2018-06-07

Among emerging pollutants, endocrine disruptors such as estradiol are of most concern. Conventional water treatment technologies not capable removing this compound from water. This study aims to assess a method that combines physicochemical and biological strategies eliminate even when there other compounds present in the matrix. Na-montmorillonite, Ca-montmorillonite zeolite were used remove medium with sulfamethoxazole, triclosan, nicotine using Plackett–Burman experimental design; each...

10.3390/eng2030020 article EN cc-by Eng—Advances in Engineering 2021-07-26

Abstract Operation conditions considerably affect the removal efficiency of wastewater treatment systems, and yet we still lack data on how these systems function under extreme dilution rates climatic at high altitudes. Here, applied two modified First-Stage French Vertical Flow Constructed Wetlands (FS-FVFCWs) for sewage in Northern Tropical Andes. Specifically, within 18 months, conducted a pilot-scale experiment hydraulic loading (HLRs) 0.94 0.56 m d−1, representing 2.5 1.5 times...

10.2166/wst.2023.201 article EN cc-by Water Science & Technology 2023-06-28

The rapid urbanization of Cuenca, Ecuador, since about 1990 has led to efforts build and operate decentralized domestic wastewater treatment systems in periurban rural areas. efficiency some these is falling, however, others are no longer working. ETAPA, the municipal institution charge water supply sanitation, evaluating them fully identify common operating maintenance difficulties, as well deficiencies design and/or construction. This paper presents an evaluation physical infrastructure...

10.2166/wpt.2017.027 article EN Water Practice & Technology 2017-03-01

Abstract BACKGROUND In this study the growth kinetics of Chlorella and Scenedesmus , isolated from a Waste Stabilization Pond were investigated under different conditions light intensity temperature. Experimental data collected by means combined respirometric titrimetric set‐up used to extend mathematical model. RESULTS The experimental results illustrated interdependent relationship temperature, which had significant influence on microalgal growth. Consequently, previously developed model...

10.1002/jctb.5131 article EN Journal of Chemical Technology & Biotechnology 2016-10-14

River flow velocity is determined by the energy available for motion and fraction lost resistance. We compared performance of different equations Darcy-Weisbach resistance coefficient (f) empirical to predict velocity. The set was tested using data from Quinuas headwater mountain river in Andean region. collected three Cascades, two Step-pools, one Plane-bed covering a wide range magnitudes. results reveal that nondimensional hydraulic geometry (NDHG) with Nash-Sutcliffe efficiency index...

10.3390/w13162207 article EN Water 2021-08-13
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