A5071590370- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive Biology and Fertility
- Ovarian function and disorders
- Prenatal Screening and Diagnostics
- Ectopic Pregnancy Diagnosis and Management
- Reproductive System and Pregnancy
- Preterm Birth and Chorioamnionitis
- Growth Hormone and Insulin-like Growth Factors
- Reproductive Health and Technologies
- Dermatologic Treatments and Research
- Endometriosis Research and Treatment
- Cancer-related Molecular Pathways
- Estrogen and related hormone effects
- Phytochemicals and Antioxidant Activities
- Genomic variations and chromosomal abnormalities
- Chronic Lymphocytic Leukemia Research
- Gestational Trophoblastic Disease Studies
- Cardiovascular Issues in Pregnancy
- Demographic Trends and Gender Preferences
- Horticultural and Viticultural Research
- Steroid Chemistry and Biochemistry
- Gestational Diabetes Research and Management
- Circadian rhythm and melatonin
- Postharvest Quality and Shelf Life Management
- Hemoglobinopathies and Related Disorders
The First Affiliated Hospital, Sun Yat-sen University
2013-2025
Sun Yat-sen University
2013-2025
Nanjing Agricultural University
2024
Key Laboratory of Guangdong Province
2016
Beijing University of Chinese Medicine
2014
Shanghai University of Traditional Chinese Medicine
2012
Sun Yat-sen Memorial Hospital
2007
UCLA Medical Center
2006
Harbor–UCLA Medical Center
2005-2006
Dalian Medical University
2005
What are the unrecognized risk factors for recurrent implantation failure (RIF) as defined in ESHRE recommendation? Anti-Müllerian hormone (AMH) is strongest predictor RIF, followed by chronic endometritis (CE), intrauterine adhesions, and BMI. Advanced age a well-known factor failure, definition of RIF was stratified 2023 recommendation. However, literature identifies other factors, including CE, endometriosis, BMI, endometrial polyps, hydrosalpinx, uterine malformation, submucosal myoma,...
Introduction:Although pre-treatment with a GnRH agonist can reduce the size of adenomyosis lesions, supra-physiological hormone level induced by controlled ovarian hyperstimulation (COH) may negate usefulness in patients leading to continued poor outcomes fresh embryo transfer cycles during IVF. It is unclear whether before starting long protocol for IVF/ICSI improve cumulative live birth rate (CLBR) infertile women adenomyosis. Method: In this retrospective cohort study, total 374 diagnosed...
Previous studies have suggested that trophoblast cells inhibit the proliferation of peripheral natural killer and level decrease in middle late pregnancy stage among healthy women. The change cell during early relationship between outcomes women with unexplained recurrent loss not been sufficiently explored.
Previous studies have shown that circadian genes might be involved in the development of polycystic ovarian syndrome (PCOS). Hyperandrogenism is a hallmark feature PCOS. However, effect hyperandrogenism on gene expression human granulosa cells unknown, and general pattern ovary unclear. Expression proteins CLOCK PER2 ovaries was observed by immunohistochemistry. The mRNA patterns CLOCK, PER2, BMAL1, steroidogenesis-related STAR, CYP11A1, HSD3B2, CYP19A1 cultured luteinized were analyzed over...
The pleiotropic effects of estrogen are mediated via stimulation two receptor (ER) subtypes, ERα and ERβ. Although a number studies have identified expression one or both subtypes in target tissues, fewer correlated ER with functional role these proteins regulating cellular excitability. In the present study, we combined fluorescence, immunocytochemistry, molecular techniques single-channel patch-clamp to determine which mediates estrogen-stimulated potassium channel activity human coronary...
Objective To compare the live birth rate and cost effectiveness of artificial cycle‐prepared frozen embryo transfer (AC‐FET) with or without GnRH agonist (GnRH‐a) pretreatment for women polycystic ovary syndrome (PCOS). Design Open‐label, randomised, controlled trial. Setting Reproductive centre a university‐affiliated hospital. Sample A total 343 PCOS, aged 24–40 years, scheduled AC‐FET receiving no more than two blastocysts. Methods The group ( n = 172) received GnRH‐a control 171) did...
This study aims to demonstrate the possible relationship between insulin-like growth factor (IGF) system and early miscarriage in polycystic ovarian syndrome (PCOS) patients with euploid embryos. 40 pregnant women included. 9 had PCOS miscarried; 20 a successful ongoing pregnancy; remaining 11 did not have miscarried. An ultrasound scan was performed prove clinical pregnancy blood sample taken on day 55 ± 4 of gestation. Serum samples IGF-1, binding protein-1 (IGFBP-1), total testosterone,...
In order to find out what extent ovarian aging could be compensated by the
Can blastocyst aneuploidy be predicted for patients with previous aneuploid pregnancy loss (PAPL) and receiving preimplantation genetic testing (PGT-A)?Multivariable logistic regression models were established to predict high risk of using four identified factors, presenting good predictive performance.Aneuploidy is the most common embryonic chromosomal abnormality leading loss. Several studies have demonstrated a higher embryo rate in PAPL, which has suggested that PGT-A should benefits...
This prospective study investigated the predictive value of pregnancy outcomes with serum human chorionic gonadotropin (hCG) 7 days after day 3 embryo transfer (D3 ET), and whether estradiol (E2) progesterone (P) improved diagnostic efficiency. The comprised 280 in vitro fertilization (IVF-ET) cycles. Serum samples were obtained D3 ET to measure hCG, E2, P concentrations. Statistical analyses conducted evaluate for outcomes. We found significant differences hCG level between non-pregnancy,...
Abstract Introduction Many studies have shown that multifetal reduction of high‐order multiple pregnancies results in improved pregnancy outcomes. However, whether conducting elective fetal from dichorionic twins after vitro fertilization ( IVF ) is worthwhile remains controversial. This study aimed to determine and embryo transfer ‐ ET associated with increased take‐home baby rate. Material methods was a retrospective cohort 3600 twin . The reduced group included 71 women transvaginal...
To examine the incidence of spontaneous fetal reduction during dichorionic diamniotic (DCDA) twin pregnancy after in vitro fertilization and embryo transfer (IVF-ET) its influence on outcomes.This was a retrospective cohort study 4447 DCDA pregnancies 14,551 singleton IVF-ET at single center between 2009 2015. The (SPR) group included 759 women. remaining 3688 women with twins showing no were non-SPR group. Outcomes compared to (n = 14,551) treated over same period. overall rate frequency...
Studies have reported a supraphysiologic estradiol (E2) level during ovarian stimulation may be related to low birthweight after fresh embryo transfer (ET), but whether high E2 in the cycle affects via frozen ET remained controversial. The study was investigate birth weight infants conceived subsequent FET. In this retrospective cohort study, 2525 singletons FET and 2668 were analyzed. incidences of small for gestational age (SGA) groups with levels did not differ significantly. Multivariate...
What is the effect of pretreatment with oral contraceptive pills (OCPs) on oocyte and embryo quality pregnancy rates in women polycystic ovary syndrome (PCOS) scheduled for IVF/ICSI cycles?
Background Selection of high-quality blastocysts is the most important factor determining success assisted reproductive technology. The objective this study to assess values blastocyst morphological quality and development speed for predicting euploidy clinical pregnancy outcome.