A5049425594- Endometriosis Research and Treatment
- Uterine Myomas and Treatments
- Endometrial and Cervical Cancer Treatments
- Building Energy and Comfort Optimization
- Reproductive System and Pregnancy
- Ectopic Pregnancy Diagnosis and Management
- Gynecological conditions and treatments
- Ovarian cancer diagnosis and treatment
- Angiogenesis and VEGF in Cancer
- Urban Heat Island Mitigation
- Gestational Trophoblastic Disease Studies
- Epigenetics and DNA Methylation
- RNA modifications and cancer
- Viral gastroenteritis research and epidemiology
- Pregnancy-related medical research
- Animal Virus Infections Studies
- Plant Virus Research Studies
- Neonatal Respiratory Health Research
- Noise Effects and Management
- Cancer, Hypoxia, and Metabolism
- Maternal and fetal healthcare
- Intraperitoneal and Appendiceal Malignancies
- Cancer-related gene regulation
- Cancer Research and Treatments
- Ferroptosis and cancer prognosis
Sixth Affiliated Hospital of Sun Yat-sen University
2021-2025
Sun Yat-sen University
2016-2025
Zhejiang University
2015-2025
University of Architecture, Civil Engineering and Geodesy
2025
Shantou University
2021-2024
Anhui University of Science and Technology
2023-2024
Anhui Science and Technology University
2023-2024
Cancer Hospital of Shantou University Medical College
2023-2024
Second Xiangya Hospital of Central South University
2024
Central South University
2024
Abstract Objectives Podocyte injury is a prediction marker of diabetic nephropathy (DN), and AKT/mTOR pathway–mediated inhibition autophagy widely reported to contribute podocyte damage. Recent study stated that sperm‐associated antigen 5 (SPAG5) activated signalling in bladder urothelial carcinoma, indicating SPAG5 might regulate play role Materials methods Apoptosis human podocytes (HPCs) were detected by flow cytometry immunofluorescence (IF). Gene level was assessed Western blot RT‐qPCR....
Boron is an essential trace element with roles in growth, development, and physiological functions; however, its mechanism of action still unclear. In this study, the regulatory PI3K/Akt signaling pathway on boron-induced changes barrier function, proliferation, apoptosis rat intestinal epithelial cells were evaluated. Occludin levels, proportion G2/M phase, cell proliferation rate, mRNA protein expression levels PCNA higher, while proportions G0/G1 S phases, caspase-3 lower treated 0.8...
Cervical cancer greatly contributes to cancer-associated mortalities worldwide. The growing incidence of cervical is primary concern, and has signaled the need for multiple treatment options. Despite preliminary responses chemotherapy and/or surgical interventions, tumors consistently relapse. Previously, natural products gained attention their diverse bioactivities, which include however are not limited to, neuroprotective, antimicrobial anticancer effects. present study evaluated activity...
The objective of this study is to summarize the experiences our department in management heterotopic pregnancy (HP) and analyze influence different treatment modality on viable intrauterine pregnancy. There were 64 patients diagnosed as HP Department Gynecology Obstetrics hospital between January 2003 June 2014, 52 with included analyzed study. Interventions expectant management, surgical transabdominal sonographic guided transvaginal aspiration ectopic gestational embryo (embryo aspiration)...
A nanodrug for targeted delivery of artesunate was synthesized to inhibit angiogenesis, serving as a non-hormonal therapy option endometriosis.
An increasing number of research have suggested that ferroptosis plays an important role in endometriosis (EMS). This study was to identify a ferroptosis-related diagnosis gene EMS by using bioinformatics. R Bioconductor package limma used analyzed the differentially expressed genes (DEGs) between groups and control groups. CIBERSORT analyze differences group 22 immune cells. Quantitative real-time PCR (RT-qPCR) Western blot (WB) were validate expression level FZD7 tissue samples. The found...
To propose a novel procedure as safe and effective treatment for cesarean scar pregnancy (CSP), cohort study was initiated in patients diagnosed with CSP treated transvaginal hysterotomy from December 2009 to March 2013, either primary or secondary therapy. All diagnoses were confirmed by both sonography pathology, gestational sac residual tissue after termination of miscarriage the section scar. Basic clinical characteristics perioperative data collected analyzed. A total 40 included. The...
A review of the evidence has indicated critical role long noncoding RNA (lncRNA) LSINCT5 in a large number human cancers. However, mechanistic involvement endometrial carcinoma (EC) is still unknown. Here authors aim to characterize expression status and elucidate its relevance EC.Relative HMGA2 were quantified by real-time polymerase chain reaction. SiRNAs employed specifically knockdown endogenous EC cells. Cell proliferation was measured with Count Kit-8 kit (CCK-8, Dojindo, Kumamoto,...
Background: Endometriosis (EMS) is an estrogen-dependent disease in which endometrial glands and stroma arise outside the uterus. Current studies have suggested that number function of immune cells are abnormal abdominal fluid ectopic lesion tissues patients with EMS. The developed CIBERSORT method allows cell profiling by deconvolution gene expression microarray data. Methods: By applying CIBERSORT, we assessed relative proportions 68 normal (NO), 112 eutopic (EU) 24 (EC). obtained profiles...
Abstract Background and Objectives The roles of thrombospondin‐1 (THBS‐1) in tumor growth metastasis are complicated its function as a cancer inhibitor or promoter remains controversial. This clinical study investigated the functional THBS‐1 gastric carcinoma by examining expression patterns protein mRNA levels during development. Methods Eighty‐two carcinomas were included this study. THBS‐1, α‐smooth muscle actin, CD34 proteins localized immunohistochemical staining, quantified real‐time...
Abstract The prevalence of TW I-type infectious bronchitis virus (IBV) has been increasing rapidly, and it become the second most common genotype IBV in China threatening poultry industry. In this study, 1-day-old specific-pathogen-free (SPF) chickens infected with were continuously observed for 200 days. affected respiratory, urinary, female reproductive systems, resulting a mortality rate 10% as well decrease egg quantity an increase inferior eggs. During monitoring period, serious lesions...
Pigment epithelium-derived factor (PEDF), an angiogenesis inhibitor with multiple other functions, balances in the eye and blocks tumor progression. Cervical cancer, angiogenesis-dependent tumor, is second most common cancer women without effective treatment. It has been reported that PEDF can inhibit several types of tumors, however, potential for treatment cervical carcinoma not well explored. The present study was designed to investigate effect recombinant on neovascularization growth...
Gene therapy has held promises for treating specific genetic diseases. However, the key to clinical application depends on effective gene delivery.
The QX-type infectious bronchitis virus (IBV) has become the predominant genotype worldwide in recent years and caused serious economic losses to chicken industry. most significant feature of QX IBV is that its infection early growing stage can cause abnormal oviduct development, resulting a high proportion 'false layers' poultry flocks laying hens breeders. However, few studies have evaluated whether infections stages also severe pathological changes oviduct.In this study, 300-day-old...
Abstract Aim We report the clinical characteristics and experience of surgical management ureteral endometriosis in our institution. Methods retrospectively reviewed data patients with hydronephrosis resulting from endometriosis. Results Forty‐six different degrees were included study; 35% had urinary tract symptoms. Concomitant involvement ipsilateral ovary occurred more than two‐thirds patients. Four nephrectomy, one which involved ureterolysis because recurrence six months later....