A5066396876- Ferroptosis and cancer prognosis
- Liver Disease Diagnosis and Treatment
- Drug Transport and Resistance Mechanisms
- Gout, Hyperuricemia, Uric Acid
- RNA modifications and cancer
- Neonatal Health and Biochemistry
- Helicobacter pylori-related gastroenterology studies
- Pharmacological Effects and Toxicity Studies
- Epigenetics and DNA Methylation
- Heme Oxygenase-1 and Carbon Monoxide
- Chronic Kidney Disease and Diabetes
- Potassium and Related Disorders
- Pregnancy and preeclampsia studies
- Peroxisome Proliferator-Activated Receptors
- Autophagy in Disease and Therapy
- Biochemical and Molecular Research
- Quinazolinone synthesis and applications
- Pancreatitis Pathology and Treatment
- Metabolism and Genetic Disorders
- Lipid metabolism and disorders
- Gastroesophageal reflux and treatments
- Pharmacogenetics and Drug Metabolism
- Cancer Research and Treatments
- Kidney Stones and Urolithiasis Treatments
- Cancer, Lipids, and Metabolism
Zhejiang University
2019-2024
Hangzhou First People's Hospital
2022-2024
Westlake University
2024
Shanghai East Hospital
2014
The function of SLC7A11 in the process ferroptosis is well-established, as it regulates synthesis glutathione (GSH), thereby influencing tumor development along with drug resistance non-small cell lung cancer (NSCLC). However, determinants governing SLC7A11's membrane trafficking and localization remain unknown. Our study identified SPTBN2 a suppressor, enhancing NSCLC cells to inducers. Mechanistically, SPTBN2, through its CH domain, interacted connected motor protein Arp1, thus...
Estrogen biosynthesis in human placental trophoblasts requires the organic anion transporter 4 (hOAT4)-mediated uptake of fetal derived precursors such as dehydroepiandrosterone-3-sulfate (DHEAS) and 16α-hydroxy-DHEA-S (16α-OH-DHEAS). Scant information is available concerning contribution metabolites on impact estrogen precursor transport followed synthesis. This study substantiated roles bilirubin well bile acids (taurochenodeoxycholic acid, taurocholic glycochenodeoxycholic...
Objective To investigate the effect of bifidobacterial adhesin (BA) on nuclear factor κB (NF-κB) and cytokines intestinal mucosa stressed rats.Methods Forty-eight rats were divided into stress group (n =24) BA using stochastic indicator method.After rat models established withfettering as condition,the experiment lasted 8 days.Both groups given enteral nutrition (EN) with heat 125.4 kJ/(kg · d) nitrogen 0.2 g/(kg d).The was fed EN plus 5 mg/ (kg adhesin,and equivalent volume normal saline [5...