- ECG Monitoring and Analysis
- Liver Disease Diagnosis and Treatment
- EEG and Brain-Computer Interfaces
- Energy Harvesting in Wireless Networks
- Peroxisome Proliferator-Activated Receptors
- Innovative Energy Harvesting Technologies
- Cancer Treatment and Pharmacology
- Analog and Mixed-Signal Circuit Design
- Advanced DC-DC Converters
- Advanced Battery Technologies Research
- Chemotherapy-induced cardiotoxicity and mitigation
- Microtubule and mitosis dynamics
- Metabolism and Genetic Disorders
- Wireless Power Transfer Systems
- Topic Modeling
- Ubiquitin and proteasome pathways
- Multilevel Inverters and Converters
- Atrial Fibrillation Management and Outcomes
- Advancements in Semiconductor Devices and Circuit Design
- Cardiovascular Health and Risk Factors
- Multimodal Machine Learning Applications
- Trace Elements in Health
- Brain Tumor Detection and Classification
- Amino Acid Enzymes and Metabolism
- Imbalanced Data Classification Techniques
Zhejiang University
2010-2025
Dali University
2024-2025
University of Science and Technology Beijing
2025
Jinhua Academy of Agricultural Sciences
2025
Women's Hospital, School of Medicine, Zhejiang University
2019
Guangdong Medical College
2016
National University of Singapore
2011-2014
Zhejiang Province Institute of Architectural Design and Research
2010-2013
Live-cell imaging of multiple subcellular structures is essential for understanding dynamics. However, the conventional multi-color sequential fluorescence microscopy suffers from significant delays and limited number structure separate labeling, resulting in substantial limitations real-time live-cell research applications. Here, we present Adaptive Explainable Multi-Structure Network (AEMS-Net), a deep-learning framework that enables simultaneous prediction two single image. The model...
Nicotinamide (NAM), a main precursor of NAD+, is essential for cellular fuel respiration, energy production, and other processes. Transporters precursors NAD+ such as nicotinic acid nicotinamide mononucleotide (NMN) have been identified, but the transporter has not elucidated. Here, we demonstrate that equilibrative nucleoside 1 2 (ENT1 2, encoded by SLC29A1 2) drive uptake establish metabolism homeostasis. In addition, ENT1/2 exhibits strong capacity to change metabolite composition...
Lithium-ion batteries that use lithium iron phosphate (LiFePO4) as the cathode material and carbon (graphite or MCMB) anode have gained significant attention due to their cost-effectiveness, low environmental impact, strong safety profile. These advantages make them suitable for a wide range of applications including electric vehicles, stationary energy storage, backup power systems. However, adoption is hindered by critical challenge: capacity degradation at elevated temperatures. This...
Background and Purpose Plasma triglyceride (TG) levels increase as gestation proceeds, abnormal elevation of TG increases the risk pregnancy complications. The current study explored mechanisms involved in hypertriglyceridaemia during pregnancy. Experimental Approach Lipid profile expression key genes liver metabolism non‐pregnant pregnant mice were studied. effects pregnancy‐related hormones on underlying uncovered vitro vivo. Key Results hepatic elevated, while fatty acid translocase...
Isthmin (ISM) is a 60 kDa secreted-angiogenesis inhibitor that suppresses tumor growth in mouse and disrupts vessel patterning zebrafish embryos. It selectively binds to alphavbeta5 (αvβ5) integrin on the surface of endothelial cells (ECs), but mechanism its antiangiogenic action remains unknown. In this work, we establish soluble ISM vitro angiogenesis induces EC apoptosis by interacting with cell receptor αvβ5 through novel 'RKD' motif localized within adhesion-associated domain MUC4 other...
Accurate location of characteristic points in wearable ECG signals may be a challenge due to the high noise. Taking time sequence waveforms and missing into account, we design regression network ECG_SCRNet, combined with sequential constraints accurately identify ECGs. We add classification head determine whether there is P-wave or T-wave missing. This architecture ensures that considers both physiological waveform class information improve accuracy locating points. The proposed ECG_SCRNet...
In this work, we share our experience on tele-knowledge pre-training for fault analysis, a crucial task in telecommunication applications that requires wide range of knowledge normally found both machine log data and product documents. To organize from experts uniformly, propose to create Tele-KG (tele-knowledge graph). Using valuable data, further tele-domain language model TeleBERT its knowledge-enhanced version, re-training KTeleBERT. which includes effective prompt hints, adaptive...
Negative sampling (NS) is widely used in knowledge graph embedding (KGE), which aims to generate negative triples make a positive-negative contrast during training. However, existing NS methods are unsuitable when multi-modal information considered KGE models. They also inefficient due their complex design. In this paper, we propose Modality-Aware Sampling (MANS) for (MMKGE) address the mentioned problems. MANS could align structural and visual embeddings entities KGs learn meaningful...
Abstract Electrocardiograms (ECGs) are a cheap and convenient means of assessing heart health provide an important basis for diagnosis treatment by cardiologists. However, existing intelligent ECG diagnostic approaches can only detect up to several tens terms, which barely cover the most common arrhythmias. Thus, further is required cardiologists in clinical settings. This paper describes development multi-expert ensemble learning model that recognize 254 terms. Based on data from 191,804...
l-Carnitine (l-Car) plays a crucial role in fatty acid <i>β</i>-oxidation. However, the plasma l-Car concentration women markedly declines during pregnancy, but underlying mechanism and its consequences on maternal hepatic <i>β</i>-oxidation have not yet been clarified. Our results showed that level mice at gestation day (GD) 18 was significantly lower than nonpregnant mice, mean fetal-to-maternal ratio GD 3.0. Carnitine/organic cation transporter 2 (OCTN2) highly expressed mouse human...
An ultra-low power boost converter for energy harvesting applications is introduced in this brief. The idle dissipation reduced to 800 nW by using a novel output voltage detector (OVD) which insensitive temperature variation and process deviation. Furthermore, constant on-time (COT)-based hysteretic burst mode controller with maximum point tracking (MPPT) technique developed ensure high efficiency wide input range. After startup, the can be set as low 30 mV. whole system designed fabricated...
An analog implementation of a novel fixed-frequency nonlinear controller for single-inductor dual-output (SIDO) buck converter in pseudo-continuous conduction mode (PCCM) is presented this paper. Both the small and large signal variations around operation point are considered to achieve better transient response so as further reduce cross regulation SIDO converter. Moreover, an internal integral loop added suppress steady-state error introduced by conventional PWM-based sliding controller....